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© Emeline Camand
Marquage par immunofluorescence d'astrocytes tumoraux ou astrocytomes (lignée cellulaire humaine U373), montrant en rouge, APC et en vert, la tubuline des microtubules. APC est un supresseur de tumeur qui est impliqué dans la polarisation des astrocytes normaux. La localisation d'APC est altérée dans des lignées de gliomes. Pour essayer de corriger, les dérèglements observés lors de la migration des cellules d'astrocytes tumuraux ou gliomes on cherche à connaitre les mécanismes moléculaires fondamentaux qui controlent la polarisation et la migration cellulaire.
Scientific Fields
Diseases
Organisms
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Projects

Project
Ongoing
7 Members

Deciphering the virulence of Legionella pneumophila in vivo in the zebrafish model (ZebraLegion)

Carmen Buchrieser (PI)

L. pneumophila -host interactions have been studied in several animal models, but they all have their weaknesses and except the guinea pig model that is rarely used, they do not well recall human infection. […]
Project
Ongoing
9 Members

Behaviour of macrophages and neutrophils in vivo

Philippe Herbomel (PI)

Emma Colucci-Guyon, Jean-Pierre Levraud, Laurent Boucontet, Milka Sarris, Maxence Fretaud The early control of potentially invading microbes by our immune system primarily depends on its main professional phagocytes – macrophages and neutrophils. While the different […]

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