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© Research
Publication : Immunity

Not so aDAMant after all: Plasticity of phagocytic microglia.

Team: Brain-immune communication
Member: Aleksandra Deczkowska
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Immunity - 11 Jun 2024

Deczkowska A

Link to Pubmed [PMID] – 38865964

Link to DOI – 10.1016/j.immuni.2024.05.013

Immunity 2024 Jun; 57(6): 1189-1191

Phagocytic microglia such as proliferative region-associated microglia and disease-associated microglia appear in the brain transiently during development and across various brain pathologies, but their function and degree of plasticity remain unclear. In this issue of Immunity, Barclay et al. established a novel Clec7a-CreERT2 mouse line to uncover the plasticity of this cell state and its role in a model of myelin injury.