Malaria-causing Plasmodium parasites thrive in humans and mosquitoes, undergoing complex transformations and rapid replication. We study their biology to find new ways to control disease and prevent transmission.
We investigate the critical stages during parasite transmission from the mosquito vector to the liver, as well as the molecular mechanisms that underlie parasite dormancy, relapse, and transmission back to mosquitoes. To uncover these processes, our team leverages rodent malaria models, bioengineered human liver systems, high-throughput imaging, single-cell and multi-omics approaches, working with both laboratory- and patient-derived parasites obtained from endemic areas.
We are based at the Institut Pasteur Paris, within the Parasite and Insect Vectors Department. We are also affiliated with Inserm and Université Paris Cité.
