Ligne de temps
Stéphanie Petrella
Chercheur(euse) Permanent(e)
18 oct. 2024
publication
Molecular mechanism of a triazole-containing inhibitor of Mycobacterium tuberculosis DNA gyrase.
Lire plus24 avr. 2023
publication
The MksG nuclease is the executing part of the bacterial plasmid defense system MksBEFG.
Lire plus26 janv. 2022
10 janv. 2022
publication
Topoisomerase I (TOP1) dynamics: conformational transition from open to closed states.
Lire plus01 nov. 2021
publication
A systematic review of Mycobacterium leprae DNA gyrase mutations and their impact on fluoroquinolone resistance.
Lire plus20 juin 2020
07 févr. 2019
publication
Overall Structures of Mycobacterium tuberculosis DNA Gyrase Reveal the Role of a Corynebacteriales GyrB-Specific Insert in ATPase Activity
Lire plus16 juin 2016
publication
Comparative study of enzymatic activities of new KatG mutants from low- and high-level isoniazid-resistant clinical isolates of Mycobacterium tuberculosis
Lire plus27 mai 2016
publication
Description of compensatory gyrA mutations restoring fluoroquinolone susceptibility in Mycobacterium tuberculosis
Lire plus20 janv. 2016
01 janv. 2016
publication
Synthesis and evaluation of original bioisosteres of bacterial type IIA topoisomerases inhibitors
Lire plus28 juil. 2015
project
ATPase inhibitors, the cases of human heat shock protein 90 and bacterial type IIA topoisomerases
Lire plus03 juil. 2015
project
Integrative structural studies of Corynebacteriales (Mycobacterium tuberculosis and Corynebacterium glutamicum) DNA gyrase (type II topoisomerase)
Lire plus01 déc. 2013
publication
Mycobacterium tuberculosis DNA gyrase ATPase domain structures suggest a dissociative mechanism that explains how ATP hydrolysis is coupled to domain motion
Lire plus01 nov. 2013
21 févr. 2012
publication
New mutations in the mycobacterial ATP synthase: new insights into the binding of the diarylquinoline TMC207 to the ATP synthase C-ring structure
Lire plus30 janv. 2012
publication
Extending the definition of the GyrB quinolone resistance-determining region in Mycobacterium tuberculosis DNA gyrase for assessing fluoroquinolone resistance in M. tuberculosis
Lire plus26 janv. 2012
publication
Purification, crystallization and preliminary X-ray crystallographic studies of the Mycobacterium tuberculosis DNA gyrase CTD
Lire plus18 juil. 2011
publication
DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis
Lire plus24 janv. 2011
publication
Crystal structure of the pyrazinamidase of Mycobacterium tuberculosis: insights into natural and acquired resistance to pyrazinamide
Lire plus18 août 2010
publication
Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase
Lire plus16 mars 2010
publication
Conservation of HHV-6 DNA polymerase processivity factor sequence and predicted structure suggests it as a target for antiviral development
Lire plus28 déc. 2009
publication
Specific structural features of the N-acetylmuramoyl-L-alanine amidase AmiD from Escherichia coli and mechanistic implications for enzymes of this family
Lire plus30 oct. 2009
publication
Purification, crystallization and preliminary X-ray diffraction experiments on the breakage-reunion domain of the DNA gyrase from Mycobacterium tuberculosis
Lire plus29 oct. 2008
publication
Crystal structure and activity of Bacillus subtilis YoaJ (EXLX1), a bacterial expansin that promotes root colonization
Lire plus14 juil. 2008
publication
Genetic and structural insights into the dissemination potential of the extremely broad-spectrum class A beta-lactamase KPC-2 identified in an Escherichia coli strain and an Enterobacter cloacae strain isolated from the same patient in France
Lire plus02 juin 2007
publication
Crystal structure of the Bacillus subtilis penicillin-binding protein 4a, and its complex with a peptidoglycan mimetic peptide
Lire plus26 févr. 2007
publication
Expression and purification of an active form of the Mycobacterium leprae DNA gyrase and its inhibition by quinolones
Lire plus01 janv. 2007
publication
Different mutations in the HHV-6 DNA polymerase gene accounting for resistance to foscarnet
Lire plus01 août 2006
publication
Genetic basis for natural and acquired resistance to the diarylquinoline R207910 in mycobacteria
Lire plus29 juin 2005
publication
Crystal structure of the Actinomadura R39 DD-peptidase reveals new domains in penicillin-binding proteins
Lire plus18 déc. 2003
publication
Crystallization and preliminary X-ray diffraction study of the class A beta-lactamase SED-1 and its mutant SED-G238C from Citrobacter sedlakii
Lire plus01 août 2001
publication
Novel class A beta-lactamase Sed-1 from Citrobacter sedlakii: genetic diversity of beta-lactamases within the Citrobacter genus
Lire plus20 juil. 2001
publication