Timeline

Stéphanie Petrella
Permanent Researcher
07 Feb 2019
publication

Overall Structures of Mycobacterium tuberculosis DNA Gyrase Reveal the Role of a Corynebacteriales GyrB-Specific Insert in ATPase Activity

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16 Jun 2016
publication

Comparative study of enzymatic activities of new KatG mutants from low- and high-level isoniazid-resistant clinical isolates of Mycobacterium tuberculosis

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27 May 2016
publication

Description of compensatory gyrA mutations restoring fluoroquinolone susceptibility in Mycobacterium tuberculosis

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20 Jan 2016
project

MM4TB

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01 Jan 2016
publication

Synthesis and evaluation of original bioisosteres of bacterial type IIA topoisomerases inhibitors

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28 Jul 2015
project

ATPase inhibitors, the cases of human heat shock protein 90 and bacterial type IIA topoisomerases

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16 Jul 2015
team

Type II topoisomerases challenges

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03 Jul 2015
project

Structural studies of type II topoisomerases

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11 May 2015
team

Structural Microbiology

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01 Dec 2013
publication

Mycobacterium tuberculosis DNA gyrase ATPase domain structures suggest a dissociative mechanism that explains how ATP hydrolysis is coupled to domain motion

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01 Nov 2013
publication

Mycobacterium tuberculosis DNA gyrase possesses two functional GyrA-boxes

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21 Feb 2012
publication

New mutations in the mycobacterial ATP synthase: new insights into the binding of the diarylquinoline TMC207 to the ATP synthase C-ring structure

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30 Jan 2012
publication

Extending the definition of the GyrB quinolone resistance-determining region in Mycobacterium tuberculosis DNA gyrase for assessing fluoroquinolone resistance in M. tuberculosis

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26 Jan 2012
publication

Purification, crystallization and preliminary X-ray crystallographic studies of the Mycobacterium tuberculosis DNA gyrase CTD

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18 Jul 2011
publication

DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis

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24 Jan 2011
publication

Crystal structure of the pyrazinamidase of Mycobacterium tuberculosis: insights into natural and acquired resistance to pyrazinamide

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18 Aug 2010
publication

Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase

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16 Mar 2010
publication

Conservation of HHV-6 DNA polymerase processivity factor sequence and predicted structure suggests it as a target for antiviral development

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28 Dec 2009
publication

Specific structural features of the N-acetylmuramoyl-L-alanine amidase AmiD from Escherichia coli and mechanistic implications for enzymes of this family

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30 Oct 2009
publication

Purification, crystallization and preliminary X-ray diffraction experiments on the breakage-reunion domain of the DNA gyrase from Mycobacterium tuberculosis

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29 Oct 2008
publication

Crystal structure and activity of Bacillus subtilis YoaJ (EXLX1), a bacterial expansin that promotes root colonization

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14 Jul 2008
publication

Genetic and structural insights into the dissemination potential of the extremely broad-spectrum class A beta-lactamase KPC-2 identified in an Escherichia coli strain and an Enterobacter cloacae strain isolated from the same patient in France

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02 Jun 2007
publication

Crystal structure of the Bacillus subtilis penicillin-binding protein 4a, and its complex with a peptidoglycan mimetic peptide

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26 Feb 2007
publication

Expression and purification of an active form of the Mycobacterium leprae DNA gyrase and its inhibition by quinolones

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01 Jan 2007
publication

Different mutations in the HHV-6 DNA polymerase gene accounting for resistance to foscarnet

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01 Aug 2006
publication

Genetic basis for natural and acquired resistance to the diarylquinoline R207910 in mycobacteria

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29 Jun 2005
publication

Crystal structure of the Actinomadura R39 DD-peptidase reveals new domains in penicillin-binding proteins

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18 Dec 2003
publication

Crystallization and preliminary X-ray diffraction study of the class A beta-lactamase SED-1 and its mutant SED-G238C from Citrobacter sedlakii

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01 Aug 2001
publication

Novel class A beta-lactamase Sed-1 from Citrobacter sedlakii: genetic diversity of beta-lactamases within the Citrobacter genus

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20 Jul 2001
publication

Crystal structures of the class D beta-lactamase OXA-13 in the native form and in complex with meropenem

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