Ligne de temps

Frédéric Bonhomme
Ingénieur(e) de Recherche
05 avr. 2024
publication

Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells

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01 avr. 2024
publication

Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization.

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15 mars 2024
publication

Facilitated Synthetic Access to Boronic Acid-Modified Nucleoside Triphosphates and Compatibility with Enzymatic DNA Synthesis

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08 janv. 2024
publication

Interrogating Aptamer Chemical Space Through Modified Nucleotide Substitution Facilitated by Enzymatic DNA Synthesis

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01 sept. 2023
publication

DAXX safeguards heterochromatin formation in embryonic stem cells

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31 août 2023
publication

A genetic screen identifies BEND3 as a regulator of bivalent gene expression and global DNA methylation

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24 juil. 2023
publication

A genome-wide screen reveals new regulators of the 2-cell-like cell state

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15 déc. 2022
publication

Enzymatic Synthesis of Vancomycin-Modified DNA

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05 janv. 2022
publication

A ruthenium-oligonucleotide bioconjugated photosensitizing aptamer for cancer cell specific photodynamic therapy

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02 nov. 2021
publication

Malaria Parasite Stress Tolerance Is Regulated by DNMT2-Mediated tRNA Cytosine Methylation

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31 oct. 2021
publication

A ruthenium-oligonucleotide bioconjugated photosensitizing aptamer for cancer cell specific photodynamic therapy

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05 août 2021
publication

Characterization of a triad of genes in cyanophage S-2L sufficient to replace adenine by 2-aminoadenine in bacterial DNA.

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03 mai 2021
publication

A genome-wide knock-out screen for actors of epigenetic silencing reveals new regulators of germline genes and 2-cell like cell state

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25 févr. 2021
project

DIM 1 HEALTH 2019 project : EpiK- The Cytosine code as potent target to kill pathogens and fight human diseases

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09 janv. 2018
team

Chimie Biologique Epigénétique

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12 sept. 2017
publication

An expedient synthesis of flexible nucleosides via a regiocontrolled enzymatic glycosylation of functionalized imidazoles

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01 août 2017
publication

Cell wall peptidolipids of Mycobacterium avium: from genetic prediction to exact structure of a nonribosomal peptide.

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01 janv. 2017
publication

Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate

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20 déc. 2016
publication

Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate

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11 mars 2016
publication

Expedient and generic synthesis of imidazole nucleosides by enzymatic transglycosylation

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01 janv. 2016
publication

Synthesis and evaluation of original bioisosteres of bacterial type IIA topoisomerases inhibitors

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03 sept. 2015
project

Inhibitors of Pseudomonas aeruginosa IMPDH

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24 juil. 2015
project

Alkoxypyrazoles, new chemical entities

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01 janv. 2012
publication

3-Methoxypyrazoles from 1,1-dimethoxyethene, few original results

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01 janv. 2011
publication

Simple preparations of 4 and 5-iodinated pyrazoles as useful building blocks

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01 janv. 2010
publication

N-arylation of 3-alkoxypyrazoles, the case of the pyridines

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01 avr. 2009
publication

Induction of a melanoma-specific antibody response by a monovalent, but not a divalent, synthetic GM2 neoglycopeptide

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01 janv. 2009
publication

Nitrogen’s reactivity of various 3-alkoxypyrazoles

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01 janv. 2008
publication

An improved preparation of 3-alkoxypyrazoles

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