Ligne de temps

Yves-Marie Coic

Ingénieur(e) de Recherche

01 janv. 2017

publication

Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate

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20 déc. 2016

publication

Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate

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11 mai 2015

team

Chimie des biomolécules

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22 janv. 2015

publication

Organization of the MADS box from human SRF revealed by tyrosine perturbation

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01 oct. 2014

publication

Low concentration structural dynamics of lanreotide and somatostatin-14

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13 janv. 2013

publication

Production and initial structural characterization of the TM4TM5 helix-loop-helix domain of the translocator protein

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25 juil. 2012

publication

Octreotide used for probing the type-II’ β-turn CD and Raman markers

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16 mars 2012

publication

Design of a specific colonic mucus marker using a human commensal bacterium cell surface domain

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27 janv. 2012

publication

A synthetic heparan sulfate-mimetic peptide conjugated to a mini CD4 displays very high anti- HIV-1 activity independently of coreceptor usage

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23 juil. 2011

publication

Direct inhibition of NF-κB activation by peptide targeting the NOA ubiquitin binding domain of NEMO

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28 févr. 2011

publication

Peptidoglycan crosslinking relaxation plays an important role in Staphylococcus aureus WalKR-dependent cell viability

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01 févr. 2010

publication

Slightly modifying pseudoproline dipeptides incorporation strategy enables solid phase synthesis of a 54 AA fragment of caveolin-1 encompassing the intramembrane domain

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24 sept. 2009

publication

Vibrational analysis of amino acids and short peptides in aqueous media. V. The effect of the disulfide bridge on the structural features of the peptide hormone somatostatin-14

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01 avr. 2009

publication

Induction of a melanoma-specific antibody response by a monovalent, but not a divalent, synthetic GM2 neoglycopeptide

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01 avr. 2009

publication

Induction of a melanoma-specific antibody response by a monovalent, but not a divalent, synthetic GM2 neoglycopeptide

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27 mars 2008

publication

Secondary and tertiary structures of the transmembrane domains of the translocator protein TSPO determined by NMR. Stabilization of the TSPO tertiary fold upon ligand binding

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05 janv. 2008

publication

Vibrational analysis of amino acids and short peptides in hydrated media. 3. Successive KL repeats induce highly stable beta-strands capable of forming non-H-bonded aggregates

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06 oct. 2007

publication

Vibrational analysis of amino acids and short peptides in hydrated media. II. Role of KLLL repeats to induce helical conformations in minimalist LK-peptides

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01 sept. 2007

publication

Inhibition of NF-kappaB activation with designed ankyrin-repeat proteins targeting the ubiquitin-binding/oligomerization domain of NEMO

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01 janv. 2006

publication

Secondary conformation of short lysine- and leucine-rich peptides assessed by optical spectroscopies: effect of chain length, concentration, solvent, and time

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15 juil. 2005

publication

Single-spanning membrane protein insertion in membrane mimetic systems: role and localization of aromatic residues

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26 mars 2005

publication

A cylinder-shaped double ribbon structure formed by an amyloid hairpin peptide derived from the beta-sheet of murine PrP: an X-ray and molecular dynamics simulation study

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05 oct. 2004

publication

Inhibition of NF-kappa B activation by peptides targeting NF-kappa B essential modulator (nemo) oligomerization

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15 avr. 2004

publication

Complex formation and vectorization of a phosphorothioate oligonucleotide with an amphipathic leucine- and lysine-rich peptide: study at molecular and cellular levels

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19 nov. 2002

publication

Deciphering the role of individual acyl chains in the interaction network between phosphatidylserines and a single-spanning membrane protein

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01 oct. 2002

publication

Most of the structural elements of the globular domain of murine prion protein form fibrils with predominant beta-sheet structure

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21 sept. 2001

publication

Investigating the conformational coupling between the transmembrane and cytoplasmic domains of a single-spanning membrane protein. A 1H-NMR study

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21 août 2001

publication

Concerted influence of key amino acids on the lipid binding properties of a single-spanning membrane protein: NMR and mutational analysis

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01 nov. 2000

publication

PMP1 18-38, a yeast plasma membrane protein fragment, binds phosphatidylserine from bilayer mixtures with phosphatidylcholine: a (2)H-NMR study

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01 janv. 1999

publication

Dodecylphosphocholine micelles as a membrane-like environment: new results from NMR relaxation and paramagnetic relaxation enhancement analysis

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01 mai 1998

publication

1H- and 2H-NMR studies of a fragment of PMP1, a regulatory subunit associated with the yeast plasma membrane H(+)-ATPase. Conformational properties and lipid-peptide interactions

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Un petit guide pour l'utilisation de la recherche avancée :

Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate

Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate

Chimie des biomolécules

Organization of the MADS box from human SRF revealed by tyrosine perturbation

Low concentration structural dynamics of lanreotide and somatostatin-14

Production and initial structural characterization of the TM4TM5 helix-loop-helix domain of the translocator protein

Octreotide used for probing the type-II’ β-turn CD and Raman markers

Design of a specific colonic mucus marker using a human commensal bacterium cell surface domain

A synthetic heparan sulfate-mimetic peptide conjugated to a mini CD4 displays very high anti- HIV-1 activity independently of coreceptor usage

Direct inhibition of NF-κB activation by peptide targeting the NOA ubiquitin binding domain of NEMO

Peptidoglycan crosslinking relaxation plays an important role in Staphylococcus aureus WalKR-dependent cell viability

Slightly modifying pseudoproline dipeptides incorporation strategy enables solid phase synthesis of a 54 AA fragment of caveolin-1 encompassing the intramembrane domain

Vibrational analysis of amino acids and short peptides in aqueous media. V. The effect of the disulfide bridge on the structural features of the peptide hormone somatostatin-14

Induction of a melanoma-specific antibody response by a monovalent, but not a divalent, synthetic GM2 neoglycopeptide

Induction of a melanoma-specific antibody response by a monovalent, but not a divalent, synthetic GM2 neoglycopeptide

Secondary and tertiary structures of the transmembrane domains of the translocator protein TSPO determined by NMR. Stabilization of the TSPO tertiary fold upon ligand binding

Vibrational analysis of amino acids and short peptides in hydrated media. 3. Successive KL repeats induce highly stable beta-strands capable of forming non-H-bonded aggregates

Vibrational analysis of amino acids and short peptides in hydrated media. II. Role of KLLL repeats to induce helical conformations in minimalist LK-peptides

Inhibition of NF-kappaB activation with designed ankyrin-repeat proteins targeting the ubiquitin-binding/oligomerization domain of NEMO

Secondary conformation of short lysine- and leucine-rich peptides assessed by optical spectroscopies: effect of chain length, concentration, solvent, and time

Single-spanning membrane protein insertion in membrane mimetic systems: role and localization of aromatic residues

A cylinder-shaped double ribbon structure formed by an amyloid hairpin peptide derived from the beta-sheet of murine PrP: an X-ray and molecular dynamics simulation study

Inhibition of NF-kappa B activation by peptides targeting NF-kappa B essential modulator (nemo) oligomerization

Complex formation and vectorization of a phosphorothioate oligonucleotide with an amphipathic leucine- and lysine-rich peptide: study at molecular and cellular levels

Deciphering the role of individual acyl chains in the interaction network between phosphatidylserines and a single-spanning membrane protein

Most of the structural elements of the globular domain of murine prion protein form fibrils with predominant beta-sheet structure

Investigating the conformational coupling between the transmembrane and cytoplasmic domains of a single-spanning membrane protein. A 1H-NMR study

Concerted influence of key amino acids on the lipid binding properties of a single-spanning membrane protein: NMR and mutational analysis

PMP1 18-38, a yeast plasma membrane protein fragment, binds phosphatidylserine from bilayer mixtures with phosphatidylcholine: a (2)H-NMR study

Dodecylphosphocholine micelles as a membrane-like environment: new results from NMR relaxation and paramagnetic relaxation enhancement analysis

1H- and 2H-NMR studies of a fragment of PMP1, a regulatory subunit associated with the yeast plasma membrane H(+)-ATPase. Conformational properties and lipid-peptide interactions