Lien vers Pubmed [PMID] – 10047575
Curr. Opin. Struct. Biol. 1999 Feb; 9(1): 14-20
Three-dimensional structural information on the integrase family of site-specific recombinases has only recently become available, with the crystal structures of catalytic domains, full-length proteins and protein-DNA complexes of this family reported over the past two years. These results have led to a model for the overall architecture and active site stereochemistry of the recombination pathway that addresses a number of interesting mechanistic issues.