[Inhibition of the tumoral growth induced by the injection of histo-incompatible cells producing interleukin-2]

Lien vers Pubmed [PMID] – 1521169

C. R. Acad. Sci. III, Sci. Vie 1992;314(11):499-504

In murine models, we show that the growth of a transplanted tumor can be controlled when allogeneic or xenogeneic cells expressing high levels of interleukin-2 are co-injected with the syngeneic tumor cells. Thus, genetically modified allogeneic or xenogeneic cells could have some therapeutic potential as vectors for transient cytokine gene expression.