From the messenger RNA saga to the transcriptome era

Lien vers Pubmed [PMID] – 14744095

C. R. Biol. 2003 Oct-Nov;326(10-11):893-900

This review attempts to provide an overview of the evolution of the ideas and techniques that prevailed at the beginning of research on ribonucleic acids, until the contemporary era of cellular transcript analysis using DNA biochips and microarrays. Certain applications derived from the use of microarrays and the corresponding analyses of transcriptomes are discussed, particularly concerning diagnosis and prevision of evolution of certain cancers.