Computational prediction of important regions in protein sequences

IEEE Signal Processing Magazine, vol. 29, issue 6, pp. 143-147

If the genomic era was characterized by the massive determination of genomic sequences, the so-called postgenomic era is, among other things, characterized by a lack of methods for obtaining functionally relevant information from these raw sequences. As the number of known protein sequences grows exponentially, it is impossible to experimentally determine their biological functions and the particular regions of these proteins responsible for such functions. For this reason, computational methods that are able to process this genomic information for extracting protein functional features are sought after.