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2022VEX1 Influences mVSG Expression During the Transition to Mammalian Infectivity in Trypanosoma brucei., Front Cell Dev Biol 2022 ; 10(): 851475.
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2021DNA double strand break position leads to distinct gene expression changes and regulates VSG switching pathway choice., PLoS Pathog 2021 Nov; 17(11): e1010038.
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2021The MRN complex promotes DNA repair by homologous recombination and restrains antigenic variation in African trypanosomes., Nucleic Acids Res 2021 Jan; (): .
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2019Monoallelic expression and epigenetic inheritance sustained by a Trypanosoma brucei variant surface glycoprotein exclusion complex, Nature Communications. In press..
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2019Persistent DNA damage foci and DNA replication with a broken chromosome in the African trypanosome, mBio in press.
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2019A post-transcriptional respiratome regulon in trypanosomes, Nucleic Acids Research, 2019 May.
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2019CRISPR in Parasitology: Not Exactly Cut and Dried!, Bryant, Jessica M. et al. Trends in Parasitology, Volume 35, Issue 6, 409 - 422.
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2018Insights into antitrypanosomal drug mode-of-action from cytology-based profiling, PLoS Negl Trop Dis. 2018 Nov 26.
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2016The nuclear envelope and gene organization in parasitic protozoa: Specializations associated with disease, Mol. Biochem. Parasitol. 2016 Sep - Oct;209(1-2):104-113.
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2016VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes, Proc. Natl. Acad. Sci. U.S.A. 2016 Jun;113(26):7225-30.
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2014Genome-scale RNAi screens for high-throughput phenotyping in bloodstream-form African trypanosomes, Nat Protoc 2015 Jan;10(1):106-33.
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2014Locus-specific control of DNA resection and suppression of subtelomeric VSG recombination by HAT3 in the African trypanosome, Nucleic Acids Res. 2014 Nov;42(20):12600-13.
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2013Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control, Cell. Microbiol. 2013 Dec;15(12):1984-93.
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2013DNA break site at fragile subtelomeres determines probability and mechanism of antigenic variation in African trypanosomes, PLoS Pathog. 2013 Mar;9(3):e1003260.
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2012Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes, Proc. Natl. Acad. Sci. U.S.A. 2012 Jul;109(27):10996-1001.
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2012High-throughput decoding of antitrypanosomal drug efficacy and resistance, Nature 2012 Feb;482(7384):232-6.
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2011High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome, Genome Res. 2011 Jun;21(6):915-24.
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2010Microhomology-mediated deletion and gene conversion in African trypanosomes, Nucleic Acids Res. 2011 Mar;39(4):1372-80.
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2009Site-specific DNA double-strand breaks greatly increase stable transformation efficiency in Trypanosoma brucei, Mol. Biochem. Parasitol. 2009 Aug;166(2):194-7.
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2008Sequence homology and microhomology dominate chromosomal double-strand break repair in African trypanosomes, Nucleic Acids Res. 2008 May;36(8):2608-18.