• 2024
  Grégoire Davignon, Natalia Pietrosemoli, Nadia Benaroudj, Marie-Estelle Soupé-Gilbert, Julie Cagliero, Élodie Turc, Mathieu Picardeau, Linda Guentas, Cyrille Goarant, Roman Thibeaux, Leptospira interrogans biofilm transcriptome highlights adaption to starvation and general stress while maintaining virulence., npj Biofilms and Microbiomes, 2024, 10 (1), pp.95. ⟨10.1038/s41522-024-00570-0⟩.
• 2024
  Giraud-Gatineau A, Nieves C, Harrison LB, Benaroudj N, Veyrier FJ, Picardeau M, Evolutionary insights into the emergence of virulent Leptospira spirochetes., PLoS Pathog 2024 Jul; 20(7): e1012161.
• 2024
  Giraud-Gatineau A, Ayachit G, Nieves C, Dagbo KC, Bourhy K, Pulido F, Huete SG, Benaroudj N, Picardeau M, Veyrier FJ, Inter-species Transcriptomic Analysis Reveals a Constitutive Adaptation Against Oxidative Stress for the Highly Virulent Leptospira Species., Mol Biol Evol 2024 Apr; 41(4): .
• 2024
  Valente M, Bramugy J, Keddie SH, Hopkins H, Bassat Q, Baerenbold O, Bradley J, Falconer J, Keogh RH, Newton PN, Picardeau M, Crump JA, Diagnosis of human leptospirosis: systematic review and meta-analysis of the diagnostic accuracy of the Leptospira microscopic agglutination test, PCR targeting Lfb1, and IgM ELISA to Leptospira fainei serovar Hurstbridge., BMC Infect Dis 2024 Feb; 24(1): 168.
• 2024
  Beauté J, Innocenti F, Aristodimou A, Špačková M, Eves C, Kerbo N, Rimhanen-Finne R, Picardeau M, Faber M, Dougas G, Halldórsdóttir AM, Jackson S, Leitēna V, Vergison A, Borg ML, Pijnacker R, Sadkowska-Todys M, Martins JV, Rusu LC, Grilc E, Estévez-Reboredo RM, Niskanen T, Westrell T, Epidemiology of reported cases of leptospirosis in the EU/EEA, 2010 to 2021., Euro Surveill 2024 Feb; 29(7): .
• 2023
  Linda Grillova, Thomas Cokelaer, Jean-François Mariet, Juliana Pipoli da Fonseca, Mathieu Picardeau, Core genome sequencing and genotyping of Leptospira interrogans in clinical samples by target capture sequencing, BMC Infectious Diseases, 2023, 23 (1), pp.157. ⟨10.1186/s12879-023-08126-x⟩.
• 2023
  Hocher A, Laursen SP, Radford P, Tyson J, Lambert C, Stevens KM, Montoya A, Shliaha PV, Picardeau M, Sockett RE, Luger K, Warnecke T, Histones with an unconventional DNA-binding mode in vitro are major chromatin constituents in the bacterium Bdellovibrio bacteriovorus., Nat Microbiol 2023 Nov; 8(11): 2006-2019.
• 2023
  Chinchilla D, Nieves C, Gutiérrez R, Sordoillet V, Veyrier FJ, Picardeau M, Phylogenomics of Leptospira santarosai, a prevalent pathogenic species in the Americas., PLoS Negl Trop Dis 2023 Nov; 17(11): e0011733.
• 2023
  Grillova L, Cokelaer T, Mariet JF, da Fonseca JP, Picardeau M, Core genome sequencing and genotyping of Leptospira interrogans in clinical samples by target capture sequencing., BMC Infect Dis 2023 Mar; 23(1): 157.
• 2023
  Nieves C, Vincent AT, Zarantonelli L, Picardeau M, Veyrier FJ, Buschiazzo A, Horizontal transfer of the rfb cluster in Leptospira is a genetic determinant of serovar identity., Life Sci Alliance 2023 Feb; 6(2): .
• 2023
  Pětrošová H, Mikhael A, Culos S, Giraud-Gatineau A, Gomez AM, Sherman ME, Ernst RK, Cameron CE, Picardeau M, Goodlett DR, Lipid A structural diversity among members of the genus Leptospira., Front Microbiol 2023 ; 14(): 1181034.
• 2023
  Garcia-Lopez M, Lorioux C, Soares A, Trombert-Paolantoni S, Harran E, Ayral F, Picardeau M, Djelouadji Z, Bourhy P, Genetic diversity of Leptospira strains circulating in humans and dogs in France in 2019-2021., Front Cell Infect Microbiol 2023 ; 13(): 1236866.
• 2022
  San Martin F, Fule L, Iraola G, Buschiazzo A, Picardeau M, , Diving into the complexity of the spirochetal endoflagellum., Trends Microbiol 2022 Oct; (): .
• 2022
  Douine M, Bonifay T, Lambert Y, Mutricy L, Galindo MS, Godin A, Bourhy P, Picardeau M, Saout M, Demar M, Sanna A, Mosnier E, Blaizot R, Couppié P, Nacher M, Adenis A, Suarez-Mutis M, Vreden S, Epelboin L, Schaub R, , Zoonoses and gold mining: A cross-sectional study to assess yellow fever immunization, Q fever, leptospirosis and leishmaniasis among the population working on illegal mining camps in French Guiana., PLoS Negl Trop Dis 2022 Aug; 16(8): e0010326.
• 2022
  Holzapfel M, Bonhomme D, Cagliero J, Vernel-Pauillac F, d'Andon MF, Bortolussi S, Fiette L, Goarant C, Wunder EA, Picardeau M, Ko AI, Werling D, Matsui M, Boneca IG, Werts C, Corrigendum: Escape of TLR5 recognition by Leptospira spp.: A rationale for atypical endoflagella., Front Immunol 2022 ; 13(): 932151.
• 2021
  Phoka T, Fule L, Da Fonseca JP, Cokelaer T, Picardeau M, Patarakul K., Investigating the role of the carbon storage regulator A (CsrA) Leptospira spp., PLoS One . 2021 Dec 13;16(12):e0260981.
• 2021
  Zavala-Alvarado C, G Huete S, Vincent AT, Sismeiro O, Legendre R, Varet H, Bussotti G, Lorioux C, Lechat P, Coppée JY, Veyrier FJ, Picardeau M, Benaroudj N, The oxidative stress response of pathogenic Leptospira is controlled by two peroxide stress regulators which putatively cooperate in controlling virulence., PLoS Pathog 2021 Dec; 17(12): e1009087.
• 2021
  Grassmann AA, Zavala-Alvarado C, Bettin EB, Picardeau M, Benaroudj N, Caimano MJ, The FUR-like regulators PerRA and PerRB integrate a complex regulatory network that promotes mammalian host-adaptation and virulence of Leptospira interrogans., PLoS Pathog 2021 Dec; 17(12): e1009078.
• 2021
  Korba AA, Lounici H, Kainiu M, Vincent AT, Mariet JF, Veyrier FJ, Goarant C, Picardeau M, , Leptospira ainlahdjerensis sp. nov., Leptospira ainazelensis sp. nov., Leptospira abararensis sp. nov. and Leptospira chreensis sp. nov., four new species isolated from water sources in Algeria., Int J Syst Evol Microbiol 2021 Dec; 71(12): .
• 2021
  Grillová L, Robinson MT, Chanthongthip A, Vincent AT, Nieves C, Oppelt J, Mariet JF, Lorioux C, Vongsouvath M, Mayxay M, Phonemeexay O, Rattanavong S, Phommasone K, Douangnouvong A, Šmajs D, Veyrier FJ, Newton PN, Picardeau M, , Genetic diversity of Leptospira isolates in Lao PDR and genome analysis of an outbreak strain., PLoS Negl Trop Dis 2021 12; 15(12): e0010076.
• 2021
  Fule L, Halifa R, Fontana C, Sismeiro O, Legendre R, Varet H, Coppée JY, Murray GL, Adler B, Hendrixson DR, Buschiazzo A, Guo S, Liu J, Picardeau M, , Role of the major determinant of polar flagellation FlhG in the endoflagella-containing spirochete Leptospira., Mol Microbiol 2021 Oct; (): .
• 2021
  Coburn J, Picardeau M, Woods CW, Veldman T, Haake DA, , Pathogenesis insights from an ancient and ubiquitous spirochete., PLoS Pathog 2021 10; 17(10): e1009836.
• 2021
  Levett PN, Picardeau M, , International Committee on Systematics of Prokaryotes Subcommittee on the taxonomy of Leptospiraceae Minutes of the closed meeting, 10 July 2019, Vancouver, British Columbia, Canada., Int J Syst Evol Microbiol 2021 Aug; 71(8): .
• 2021
  Goarant C, Dellagi K, Picardeau M, , Ending the Neglect of Treatable Bacterial Zoonoses Responsible for Non-Malaria Fevers., Yale J Biol Med 2021 Jun; 94(2): 351-360.
• 2021
  Jayasundara D, Senavirathna I, Warnasekara J, Gamage C, Siribaddana S, Kularatne SAM, Matthias M, Mariet JF, Picardeau M, Agampodi S, Vinetz JM, , Correction: 12 Novel clonal groups of Leptospira infecting humans in multiple contrasting epidemiological contexts in Sri Lanka., PLoS Negl Trop Dis 2021 May; 15(5): e0009471.
• 2021
  Casanovas-Massana A, Vincent AT, Bourhy P, Neela VK, Veyrier FJ, Picardeau M, Wunder EA, , Leptospira dzianensis and Leptospira putramalaysiae are later heterotypic synonyms of Leptospira yasudae and Leptospira stimsonii., Int J Syst Evol Microbiol 2021 Feb; (): .
• 2021
  Houéménou H, Gauthier P, Houéménou G, Mama D, Alassane A, Socohou A, Dossou HJ, Badou S, Picardeau M, Tweed S, Leblanc M, Dobigny G, , Pathogenic Leptospira and water quality in African cities: A case study of Cotonou, Benin., Sci Total Environ 2021 Feb; 774(): 145541.
• 2021
  Richard E, Bourhy P, Picardeau M, Moulin L, Wurtzer S, , Effect of disinfection agents and quantification of potentially viable Leptospira in fresh water samples using a highly sensitive integrity-qPCR assay., PLoS One 2021 ; 16(5): e0251901.
• 2021
  Phoka T, Fule L, Da Fonseca JP, Cokelaer T, Picardeau M, Patarakul K, , Investigating the role of the carbon storage regulator A (CsrA) in Leptospira spp., PLoS One 2021 ; 16(12): e0260981.
• 2020
  Gaultney RA, Vincent AT, Lorioux C, Coppée JY, Sismeiro O, Varet H, Legendre R, Cockram CA, Veyrier FJ, Picardeau M, , 4-Methylcytosine DNA modification is critical for global epigenetic regulation and virulence in the human pathogen Leptospira interrogans., Nucleic Acids Res 2020 Dec; 48(21): 12102-12115.
• 2020
  Picardeau M, , Toolbox of Molecular Techniques for Studying Leptospira Spp., Curr Top Microbiol Immunol ; 415(): 141-162.
• 2020
  Zavala-Alvarado C, Sismeiro O, Legendre R, Varet H, Bussotti G, Bayram J, G Huete S, Rey G, Coppée JY, Picardeau M, Benaroudj N, The transcriptional response of pathogenic Leptospira to peroxide reveals new defenses against infection-related oxidative stress., PLoS Pathog 2020 Oct; 16(10): e1008904.
• 2020
  Grillová L, Angermeier H, Levy M, Giard M, Lastère S, Picardeau M, , Circulating genotypes of Leptospira in French Polynesia : An 9-year molecular epidemiology surveillance follow-up study., PLoS Negl Trop Dis 2020 09; 14(9): e0008662.
• 2020
  Guglielmini J, Bourhy P, Schiettekatte O, Zinini F, Brisse S, Picardeau M, , Correction: Genus-wide Leptospira core genome multilocus sequence typing for strain taxonomy and global surveillance., PLoS Negl Trop Dis 2020 08; 14(8): e0008673.
• 2020
  Kallel H, Bourhy P, Mayence C, Houcke S, Hommel D, Picardeau M, Caro V, Matheus S, , First report of human Leptospira santarosai infection in French Guiana., J Infect Public Health 2020 Aug; 13(8): 1181-1183.
• 2020
  Piredda I, Palmas B, Noworol M, Tola S, Longheu C, Bertasio C, Scaltriti E, Denurra D, Cherchi M, Picardeau M, Boniotti MB, Ponti MN, , Isolation of Leptospira interrogans from a Bottlenose Dolphin (Tursiops truncatus) in the Mediterranean Sea., J. Wildl. Dis. 2020 07; 56(3): 727-729.
• 2020
  Thibeaux R, Soupé-Gilbert ME, Kainiu M, Girault D, Bierque E, Fernandes J, Bähre H, Douyère A, Eskenazi N, Vinh J, Picardeau M, Goarant C, , The zoonotic pathogen Leptospira interrogans mitigates environmental stress through cyclic-di-GMP-controlled biofilm production., NPJ Biofilms Microbiomes 2020 06; 6(1): 24.
• 2020
  Gibson KH, Trajtenberg F, Wunder EA, Brady MR, San Martin F, Mechaly A, Shang Z, Liu J, Picardeau M, Ko A, Buschiazzo A, Sindelar CV, , An asymmetric sheath controls flagellar supercoiling and motility in the leptospira spirochete., Elife 2020 Mar; 9(): .
• 2020
  Holzapfel M, Bonhomme D, Cagliero J, Vernel-Pauillac F, Fanton d'Andon M, Bortolussi S, Fiette L, Goarant C, Wunder EA, Picardeau M, Ko AI, Werling D, Matsui M, Boneca IG, Werts C, , Escape of TLR5 Recognition by Leptospira spp.: A Rationale for Atypical Endoflagella., Front Immunol 2020 ; 11(): 2007.
• 2020
  Picardeau M, , Leptospira and Leptospirosis., Methods Mol. Biol. 2020 ; 2134(): 271-275.
• 2020
  Grillová L, Picardeau M, , Core Genome Multi-locus Sequence Typing Analyses of Leptospira spp. Using the Bacterial Isolate Genome Sequence Database., Methods Mol. Biol. 2020 ; 2134(): 11-21.
• 2020
  El Azhari M, Picardeau M, Cherkaoui I, Anouar Sadat M, Moumni H, Marhoum El Filali K, Ghazal H, Maaroufi A, Hamdi S, El Mdaghri N, Bourhy P, , Seroprevalence of Leptospirosis among High-Risk Individuals in Morocco., Interdiscip Perspect Infect Dis 2020 ; 2020(): 5236045.
• 2020
  Noda AA, Grillová L, Mariet JF, Paiffer NB, Ruiz YC, Rodríguez I, Echevarría E, Obregón AM, Lienhard R, Picardeau M, , A first insight into the genomic diversity of Leptospira strains isolated from patients in Cuba., PLoS ONE 2020 ; 15(2): e0229673.
• 2020
  Schiettekatte O, Bourhy P, , Isolation, Purification, and Characterization of Leptophages., Methods Mol Biol 2020 ; 2134(): 67-75.
• 2019
  Miailhe AF, Mercier E, Maamar A, Lacherade JC, Le Thuaut A, Gaultier A, Asfar P, Argaud L, Ausseur A, Ben Salah A, Botoc V, Chaoui K, Charpentier J, Cracco C, De Prost N, Eustache ML, Ferré A, Gauvin E, Goursaud S, Grall M, Guiot P, Jonas M, Lambiotte F, Landais M, Lemarié J, Lesieur O, Lhommet C, Michel P, Monseau Y, Moschietto S, Nseir S, Osman D, Pillot J, Piton G, Sedillot N, Sirodot M, Thevenin D, Zafrani L, Zerbib Y, Bourhy P, Lascarrou JB, Reignier J, , , Severe leptospirosis in non-tropical areas: a nationwide, multicentre, retrospective study in French ICUs., Intensive Care Med 2019 12; 45(12): 1763-1773.
• 2019
  Le Turnier P, Bonifay T, Mosnier E, Schaub R, Jolivet A, Demar M, Bourhy P, Nacher M, Djossou F, Epelboin L, , Usefulness of C-Reactive Protein in Differentiating Acute Leptospirosis and Dengue Fever in French Guiana., Open Forum Infect Dis 2019 Sep; 6(9): ofz323.
• 2019
  Grillová L, Oppelt J, Mikalová L, Nováková M, Giacani L, Niesnerová A, Noda AA, Mechaly AE, Pospíšilová P, Čejková D, Grange PA, Dupin N, Strnadel R, Chen M, Denham I, Arora N, Picardeau M, Weston C, Forsyth RA, Šmajs D, Directly Sequenced Genomes of Contemporary Strains of Syphilis Reveal Recombination-Driven Diversity in Genes Encoding Predicted Surface-Exposed Antigens, Front Microbiol 2019;10:1691.
• 2019
  Goarant C, Picardeau M, Morand S, McIntyre KM, Leptospirosis under the bibliometrics radar: evidence for a vicious circle of neglect, J Glob Health 2019 Jun;9(1):010302.
• 2019
  Vincent AT, Schiettekatte O, Goarant C, Neela VK, Bernet E, Thibeaux R, Ismail N, Mohd Khalid MKN, Amran F, Masuzawa T, Nakao R, Amara Korba A, Bourhy P, Veyrier FJ, Picardeau M, , Revisiting the taxonomy and evolution of pathogenicity of the genus Leptospira through the prism of genomics., PLoS Negl Trop Dis 2019 05; 13(5): e0007270.
• 2019
  Rahelinirina S, Bourhy P, Andriamiaramanana F, Garin B, Rajerison M, , High Prevalence of Leptospira spp. in Rodents in an Urban Setting in Madagascar., Am J Trop Med Hyg 2019 05; 100(5): 1079-1081.
• 2019
  Guglielmini J, Bourhy P, Schiettekatte O, Zinini F, Brisse S, Picardeau M, , Genus-wide Leptospira core genome multilocus sequence typing for strain taxonomy and global surveillance., PLoS Negl Trop Dis 2019 04; 13(4): e0007374.
• 2019
  Fernandes LGV, Guaman LP, Vasconcellos SA, Heinemann MB, Picardeau M, Nascimento ALTO, Gene silencing based on RNA-guided catalytically inactive Cas9 (dCas9): a new tool for genetic engineering in Leptospira, Sci Rep 2019 Feb;9(1):1839.
• 2019
  Grillova L, Jolley K, Šmajs D, Picardeau M, A public database for the new MLST scheme for subsp. : surveillance and epidemiology of the causative agent of syphilis, PeerJ 2019;6:e6182.
• 2018
  Guillois Y, Bourhy P, Ayral F, Pivette M, Decors A, Aranda Grau JH, Champenois B, Malhère C, Combes B, Richomme C, Le Guyader M, King LA, Septfons A, , An outbreak of leptospirosis among kayakers in Brittany, North-West France, 2016., Euro Surveill 2018 Nov; 23(48): .
• 2018
  Eshghi A, Gaultney RA, England P, Brûlé S, Miras I, Sato H, Coburn J, Bellalou J, Moriarty TJ, Haouz A, Picardeau M, An extracellular Leptospira interrogans leucine-rich repeat protein binds human E- and VE-cadherins, Cell. Microbiol. 2019 02;21(2):e12949.
• 2018
  Zarantonelli L, Suanes A, Meny P, Buroni F, Nieves C, Salaberry X, Briano C, Ashfield N, Da Silva Silveira C, Dutra F, Easton C, Fraga M, Giannitti F, Hamond C, Macías-Rioseco M, Menéndez C, Mortola A, Picardeau M, Quintero J, Ríos C, Rodríguez V, Romero A, Varela G, Rivero R, Schelotto F, Riet-Correa F, Buschiazzo A, , Isolation of pathogenic Leptospira strains from naturally infected cattle in Uruguay reveals high serovar diversity, and uncovers a relevant risk for human leptospirosis, PLoS Negl Trop Dis 2018 Sep;12(9):e0006694.
• 2018
  Azad Eshghi Robert A. Gaultney Patrick England Sébastien Brûlé Isabelle Miras Hiromi Sato Jenifer Coburn Jacques Bellalou Tara J. Moriarty Ahmed Haouz Mathieu Picardeau, An extracellular Leptospira interrogans leucine‐rich repeat protein binds human E‐ and VE‐cadherins, Eshghi, A, Gaultney, RA, England, P, et al. An extracellular Leptospira interrogans leucine‐rich repeat protein binds human E‐ and VE‐cadherins. Cellular Microbiology. 2019; 21:e12949. .
• 2018
  Levett PN, Picardeau M, International Committee on Systematics of Prokaryotes Subcommittee on the Taxonomy of Leptospiraceae. Minutes of the closed meeting, 28 November 2017, Palmerston North, New Zealand, Int. J. Syst. Evol. Microbiol. 2018 Oct;68(10):3362.
• 2018
  Schiettekatte O, Vincent AT, Malosse C, Lechat P, Chamot-Rooke J, Veyrier FJ, Picardeau M, Bourhy P, , Characterization of LE3 and LE4, the only lytic phages known to infect the spirochete Leptospira., Sci Rep 2018 08; 8(1): 11781.
• 2018
  Zida S, Kania D, Sotto A, Brun M, Picardeau M, Castéra J, Bolloré K, Kagoné T, Traoré J, Ouoba A, Dujols P, Van de Perre P, Méda N, Tuaillon E, Leptospirosis as Cause of Febrile Icteric Illness, Burkina Faso, Emerging Infect. Dis. 2018 Aug;24(8):1569-1572.
• 2018
  Le Turnier P, Mosnier E, Schaub R, Bourhy P, Jolivet A, Cropet C, Villemant N, Trombert-Paolantoni S, Berlioz-Arthaud A, Nacher M, Demar M, Picardeau M, Djossou F, Epelboin L, Epidemiology of Human Leptospirosis in French Guiana (2007-2014): A Retrospective Study, Am. J. Trop. Med. Hyg. 2018 Sep;99(3):590-596.
• 2018
  Santos LA, Adhikarla H, Yan X, Wang Z, Fouts DE, Vinetz JM, Alcantara LCJ, Hartskeerl RA, Goris MGA, Picardeau M, Reis MG, Townsend JP, Zhao H, Ko AI, Wunder EA, Genomic Comparison Among Global Isolates of Serovars Copenhageni and Icterohaemorrhagiae Identified Natural Genetic Variation Caused by an Indel, Front Cell Infect Microbiol 2018;8:193.
• 2018
  Wunder EA, Slamti L, Suwondo DN, Gibson KH, Shang Z, Sindelar CV, Trajtenberg F, Buschiazzo A, Ko AI, Picardeau M, FcpB Is a Surface Filament Protein of the Endoflagellum Required for the Motility of the Spirochete, Front Cell Infect Microbiol 2018;8:130.
• 2018
  Thibeaux R, Girault D, Bierque E, Soupé-Gilbert ME, Rettinger A, Douyère A, Meyer M, Iraola G, Picardeau M, Goarant C, Biodiversity of Environmental : Improving Identification and Revisiting the Diagnosis, Front Microbiol 2018;9:816.
• 2018
  Zhang JJ, Hu WL, Yang Y, Li H, Picardeau M, Yan J, Yang XF, The sigma factor σ is required for the long-term survival of Leptospira biflexa in water, Mol. Microbiol. 2018 Apr;.
• 2018
  Adhikarla H, Wunder EA, Mechaly AE, Mehta S, Wang Z, Santos L, Bisht V, Diggle P, Murray G, Adler B, Lopez F, Townsend JP, Groisman E, Picardeau M, Buschiazzo A, Ko AI, Lvr, a Signaling System That Controls Global Gene Regulation and Virulence in Pathogenic, Front Cell Infect Microbiol 2018;8:45.
• 2018
  Puche R, Ferrés I, Caraballo L, Rangel Y, Picardeau M, Takiff H, Iraola G, , Leptospira venezuelensis sp. nov., a new member of the intermediate group isolated from rodents, cattle and humans., Int J Syst Evol Microbiol 2018 Feb; 68(2): 513-517.
• 2018
  Kebouchi M, Saul F, Taher R, Landier A, Beaudeau B, Dubrac S, Weber P, Haouz A, Picardeau M, Benaroudj N, Structure and function of the Leptospira interrogans peroxide stress regulator (PerR), an atypical PerR devoid of a structural metal-binding site., J Biol Chem 2018 Jan; 293(2): 497-509.
• 2018
  Thibeaux R, Iraola G, Ferrés I, Bierque E, Girault D, Soupé-Gilbert ME, Picardeau M, Goarant C, Deciphering the unexplored Leptospira diversity from soils uncovers genomic evolution to virulence, Microb Genom 2018 Jan;.
• 2018
  Liegeon G, Delory T, Picardeau M, Antibiotic susceptibilities of livestock isolates of leptospira, Int. J. Antimicrob. Agents 2018 Jan;.
• 2017
  Ratet G, Santecchia I, Fanton d'Andon M, Vernel-Pauillac F, Wheeler R, Lenormand P, Fischer F, Lechat P, Haake DA, Picardeau M, Boneca IG, Werts C, , LipL21 lipoprotein binding to peptidoglycan enables Leptospira interrogans to escape NOD1 and NOD2 recognition., PLoS Pathog 2017 12; 13(12): e1006725.
• 2017
  Cassadou S, Rosine J, Flamand C, Escher M, Ledrans M, Bourhy P, Picardeau M, Quénel P, , Correction: Underestimation of Leptospirosis Incidence in the French West Indies., PLoS Negl Trop Dis 2017 12; 11(12): e0006128.
• 2017
  Mori M, Bourhy P, Le Guyader M, Van Esbroeck M, Djelouadji Z, Septfons A, Kodjo A, Picardeau M, Pet rodents as possible risk for leptospirosis, Belgium and France, 2009 to 2016, Euro Surveill. 2017 Oct;22(43).
• 2017
  Epelboin L, Bourhy P, Le Turnier P, Schaub R, Mosnier E, Berlioz-Arthaud A, Reynaud Y, Nacher M, De Thoisy B, Carles G, Richard-Hansen C, Demar M, Picardeau M, Djossou F, , [Leptospirosis in French Guiana and the Guiana shield: Current knowledge in 2016]., Bull Soc Pathol Exot 2017 Aug; 110(3): 165-179.
• 2017
  Latifah I, Abdul Halim A, Rahmat MS, Nadia MF, Ubil ZE, Asmah H, Shafariatul Akmar I, Picardeau M, Siti Haslina O, Nasir MA, , Isolation by culture and PCR identification of LipL32 gene of pathogenic Leptospira spp. in wild rats of Kuala Lumpur., Malays J Pathol 2017 08; 39(2): 161-166.
• 2017
  Courdurie C, Le Govic Y, Bourhy P, Alexer D, Pailla K, Theodose R, Cesaire R, Rosine J, Hochedez P, Olive C, , Evaluation of different serological assays for early diagnosis of leptospirosis in Martinique (French West Indies)., PLoS Negl Trop Dis 2017 Jun; 11(6): e0005678.
• 2017
  Picardeau M, Virulence of the zoonotic agent of leptospirosis: still terra incognita?, Nat. Rev. Microbiol. 2017 May;15(5):297-307.
• 2017
  San Martin F, Mechaly AE, Larrieux N, Wunder EA, Ko AI, Picardeau M, Trajtenberg F, Buschiazzo A, Crystallization of FcpA from Leptospira, a novel flagellar protein that is essential for pathogenesis, Acta Crystallogr F Struct Biol Commun 2017 03;73(Pt 3):123-129.
• 2017
  Penna B, Marassi CD, Libonati H, Narduche L, Lilenbaum W, Bourhy P, , Diagnostic accuracy of an in-house ELISA using the intermediate species Leptospira fainei as antigen for diagnosis of acute leptospirosis in dogs., Comp Immunol Microbiol Infect Dis 2017 Feb; 50(): 13-15.
• 2017
  Zhukova A, Fernandes LG, Hugon P, Pappas CJ, Sismeiro O, Coppée JY, Becavin C, Malabat C, Eshghi A, Zhang JJ, Yang FX, Picardeau M, Genome-Wide Transcriptional Start Site Mapping and sRNA Identification in the Pathogen Leptospira interrogans, Front Cell Infect Microbiol 2017;7:10.
• 2017
  Hu WL, Pappas CJ, Zhang JJ, Yang YY, Yan J, Picardeau M, Yang XF, The EbpA-RpoN Regulatory Pathway of the Pathogen Leptospira interrogans Is Essential for Survival in the Environment, Appl. Environ. Microbiol. 2017 Feb;83(3).
• 2017
  Amélie Desvars-Larrive, Michel Pascal, Patrick Gasqui, Jean-François Cosson, Etienne Benoit, Virginie Lattard, Laurent Crespin, Olivier Lorvelec, Benoît Pisanu, Alexandre Teynié, Muriel Vayssier Taussat, Sarah Bonnet, Philippe Marianneau, Sandra Lacôte, Pascale Bourhy, Philippe Berny, Nicole Pavio, Sophie Le Poder, Emmanuelle Gilot-Fromont, Elsa Jourdain, Abdessalem Hammed, Isabelle Fourel, Farid Chikh, Gwenaël Vourc’h, Population genetics, community of parasites, and resistance to rodenticides in an urban brown rat (Rattus norvegicus) population, PLoS ONE, 2017, 79 (113), pp.e0184015. ⟨10.1371/journal.pone.0184015⟩.
• 2016
  Wunder EA, Figueira CP, Benaroudj N, Hu B, Tong BA, Trajtenberg F, Liu J, Reis MG, Charon NW, Buschiazzo A, Picardeau M, Ko AI, A novel flagellar sheath protein, FcpA, determines filament coiling, translational motility and virulence for the Leptospira spirochete., Mol Microbiol 2016 Aug; 101(3): 457-70.
• 2016
  Wunder EA, Figueira CP, Santos GR, Lourdault K, Matthias MA, Vinetz JM, Ramos E, Haake DA, Picardeau M, Dos Reis MG, Ko AI, Real-time PCR reveals rapid dissemination of Leptospira interrogans after intraperitoneal and conjunctival inoculation of hamsters, Infect. Immun. 2016 May;.
• 2016
  Cassadou S, Rosine J, Flamand C, Escher M, Ledrans M, Bourhy P, Picardeau M, Quénel P, Underestimation of Leptospirosis Incidence in the French West Indies, PLoS Negl Trop Dis 2016 Apr;10(4):e0004668.
• 2016
  Fontana C, Lambert A, Benaroudj N, Gasparini D, Gorgette O, Cachet N, Bomchil N, Picardeau M, Analysis of a Spontaneous Non-Motile and Avirulent Mutant Shows That FliM Is Required for Full Endoflagella Assembly in Leptospira interrogans., PLoS One 2016 ; 11(4): e0152916.
• 2016
  Hem S, Ly S, Votsi I, Vogt F, Asgari N, Buchy P, Heng S, Picardeau M, Sok T, Ly S, Huy R, Guillard B, Cauchemez S, Tarantola A, Estimating the Burden of Leptospirosis among Febrile Subjects Aged below 20 Years in Kampong Cham Communities, Cambodia, 2007-2009, PLoS ONE 2016;11(4):e0151555.
• 2016
  Loureiro AP, Hamond C, Pinto P, Bremont S, Bourhy P, Lilenbaum W, , Molecular analysis of leptospires from serogroup Sejroe obtained from asymptomatic cattle in Rio de Janeiro – Brazil reveals genetic proximity to serovar Guaricura., Res Vet Sci 2016 Apr; 105(): 249-53.
• 2016
  Castiblanco-Valencia MM, Fraga TR, Breda LC, Vasconcellos SA, Figueira CP, Picardeau M, Wunder E, Ko AI, Barbosa AS, Isaac L, Acquisition of negative complement regulators by the saprophyte Leptospira biflexa expressing LigA or LigB confers enhanced survival in human serum, Immunol. Lett. 2016 Mar;173:61-68.
• 2016
  Fouts DE, Matthias MA, Adhikarla H, Adler B, Amorim-Santos L, Berg DE, Bulach D, Buschiazzo A, Chang YF, Galloway RL, Haake DA, Haft DH, Hartskeerl R, Ko AI, Levett PN, Matsunaga J, Mechaly AE, Monk JM, Nascimento AL, Nelson KE, Palsson B, Peacock SJ, Picardeau M, Ricaldi JN, Thaipandungpanit J, Wunder EA, Yang XF, Zhang JJ, Vinetz JM, What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira, PLoS Negl Trop Dis 2016 Feb;10(2):e0004403.
• 2016
  Eshghi A, Henderson JC, Trent MS, Picardeau M, Erratum for Eshghi et al., Leptospira interrogans lpxD Homologue Is Required for Thermal Acclimatization and Virulence, Infect. Immun. 2016 Feb;84(2):607.
• 2015
  Levett PN, Picardeau M, International Committee on Systematics of ProkaryotesSubcommittee on the taxonomy of LeptospiraceaeMinutes of the closed meeting, 8 October 2015, Semarang, Indonesia, Int. J. Syst. Evol. Microbiol. 2016 Jan;66(1):523.
• 2015
  Hochedez P, Theodose R, Olive C, Bourhy P, Hurtrel G, Vignier N, Mehdaoui H, Valentino R, Martinez R, Delord JM, Herrmann C, Lamaury I, Césaire R, Picardeau M, Cabié A, Factors Associated with Severe Leptospirosis, Martinique, 2010-2013, Emerging Infect. Dis. 2015 Dec;21(12):2221-4.
• 2015
  Dobigny G, Garba M, Tatard C, Loiseau A, Galan M, Kadaouré I, Rossi JP, Picardeau M, Bertherat E, Urban Market Gardening and Rodent-Borne Pathogenic Leptospira in Arid Zones: A Case Study in Niamey, Niger, PLoS Negl Trop Dis 2015 Oct;9(10):e0004097.
• 2015
  Picardeau M, Leptospirosis: Updating the Global Picture of an Emerging Neglected Disease, PLoS Negl Trop Dis 2015 Sep;9(9):e0004039.
• 2015
  Hamond C, Martins G, Bremont S, Medeiros MA, Bourhy P, Lilenbaum W, , Molecular Characterization and Serology of Leptospira kirschneri (Serogroup Grippotyphosa) Isolated from Urine of a Mare Post-Abortion in Brazil., Zoonoses Public Health 2016 May; 63(3): 191-5.
• 2015
  Pappas CJ, Picardeau M., Control of gene expression in Leptospira spp. by Transcription Activator-Like Effectors (TALEs) demonstrates a potential role for LigA and LigB in virulence in L. interrogans., Appl Environ Microbiol. 2015 Sep 4..
• 2015
  Eshghi A, Henderson J, Trent MS, Picardeau M., Leptospira interrogans lpxD Homologue is Required for Thermal Acclimatization and Virulence., Infect Immun. 2015 Aug 17..
• 2015
  Pagès F, Larrieu S, Simoes J, Lenabat P, Kurtkowiak B, Guernier V, Le Minter G, Lagadec E, Gomard Y, Michault A, Jaffar-Bandjee MC, Dellagi K, Picardeau M, Tortosa P, Filleul L, Investigation of a leptospirosis outbreak in triathlon participants, Réunion Island, 2013, Epidemiol. Infect. 2016 Feb;144(3):661-9.
• 2015
  Naze F, Desvars A, Picardeau M, Bourhy P, Michault A, Use of a New High Resolution Melting Method for Genotyping Pathogenic Leptospira spp, PLoS ONE 2015;10(7):e0127430.
• 2015
  Pailhoriès H, Buzelé R, Picardeau M, Robert S, Mercier E, Mereghetti L, Lanotte P, Molecular characterization of Leptospira sp by multilocus variable number tandem repeat analysis (MLVA) from clinical samples: a case report, Int. J. Infect. Dis. 2015 Aug;37:119-21.
• 2015
  Scharrig E, Carestia A, Ferrer MF, Cédola M, Pretre G, Drut R, Picardeau M, Schattner M, Gómez RM., Neutrophil Extracellular Traps are Involved in the Innate Immune Response to Infection with Leptospira., PLoS Negl Trop Dis. 2015 Jul 10;9(7):e0003927.
• 2015
  Miras I, Saul F, Nowakowski M, Weber P, Haouz A, Shepard W, Picardeau M, Structural characterization of a novel subfamily of leucine-rich repeat proteins from the human pathogen Leptospira interrogans, Acta Crystallogr. D Biol. Crystallogr. 2015 Jun;71(Pt 6):1351-9.
• 2015
  Eshghi A, Pappalardo E, Hester S, Thomas B, Pretre G, Picardeau M, Pathogenic Leptospira interrogans Exoproteins Are Primarily Involved in Heterotrophic Processes, Infect. Immun. 2015 Aug;83(8):3061-73.
• 2015
  Pappas CJ, Benaroudj N, Picardeau M, A replicative plasmid vector allows efficient complementation of pathogenic Leptospira strains., Appl Environ Microbiol 2015 May; 81(9): 3176-81.
• 2015
  Hamond C, Pinna M, Medeiros MA, Bourhy P, Lilenbaum W, Picardeau M, A multilocus variable number tandem repeat analysis assay provides high discrimination for genotyping Leptospira santarosai strains, J. Med. Microbiol. 2015 May;64(Pt 5):507-12.
• 2015
  Picardeau M, Genomics, proteomics, and genetics of leptospira, Curr. Top. Microbiol. Immunol. 2015;387:43-63.
• 2014
  Lambert A, Wong Ng J, Picardeau M, Gene inactivation of a chemotaxis operon in the pathogen Leptospira interrogans, FEMS Microbiol. Lett. 2015 Jan;362(3):1-8.
• 2014
  Bourhy P, Collet L, Brisse S, Picardeau M., Leptospira mayottensis sp. nov., a pathogenic species of the genus Leptospira isolated from humans., Int J Syst Evol Microbiol. 2014 Dec;64(Pt 12):4061-7.
• 2014
  Bourhy P, Collet L, Brisse S, Picardeau M, Leptospira mayottensis sp. nov., a pathogenic species of the genus Leptospira isolated from humans, Int. J. Syst. Evol. Microbiol. 2014 Dec;64(Pt 12):4061-7.
• 2014
  Morero NR, Botti H, Nitta KR, Carrión F, Obal G, Picardeau M, Buschiazzo A, HemR is an OmpR/PhoB-like response regulator from Leptospira, which simultaneously effects transcriptional activation and repression of key haem metabolism genes, Mol. Microbiol. 2014 Oct;94(2):340-52.
• 2014
  Martins G, Loureiro AP, Hamond C, Pinna MH, Bremont S, Bourhy P, Lilenbaum W, First isolation of Leptospira noguchii serogroups Panama and Autumnalis from cattle, Epidemiol. Infect. 2015 May;143(7):1538-41.
• 2014
  Pětrošová H, Picardeau M, Screening of a Leptospira biflexa mutant library to identify genes involved in ethidium bromide tolerance, Appl. Environ. Microbiol. 2014 Oct;80(19):6091-103.
• 2014
  Cosson JF, Picardeau M, Mielcarek M, Tatard C, Chaval Y, Suputtamongkol Y, Buchy P, Jittapalapong S, Herbreteau V, Morand S, Epidemiology of leptospira transmitted by rodents in southeast Asia, PLoS Negl Trop Dis 2014 Jun;8(6):e2902.
• 2014
  Eshghi A, Becam J, Lambert A, Sismeiro O, Dillies MA, Jagla B, Wunder EA, Ko AI, Coppee JY, Goarant C, Picardeau M, A putative regulatory genetic locus modulates virulence in the pathogen Leptospira interrogans, Infect. Immun. 2014 Jun;82(6):2542-52.
• 2014
  Lilenbaum W, Kremer F, Ristow P, Dellagostin O, Bourhy P, Hartskeerl R, Vasconcellos S, , Molecular characterization of the first leptospires isolated from goats in Brazil., Braz J Microbiol 2014 ; 45(4): 1527-30.
• 2013
  Benaroudj N, Saul F, Bellalou J, Miras I, Weber P, Bondet V, Murray GL, Adler B, Ristow P, Louvel H, Haouz A, Picardeau M, Structural and functional characterization of an orphan ATP-binding cassette ATPase involved in manganese utilization and tolerance in Leptospira spp., J Bacteriol 2013 Dec; 195(24): 5583-91.
• 2013
  Picardeau M, Bertherat E, Jancloes M, Skouloudis AN, Durski K, Hartskeerl RA, Rapid tests for diagnosis of leptospirosis: current tools and emerging technologies, Diagn. Microbiol. Infect. Dis. 2014 Jan;78(1):1-8.
• 2013
  Bourhy P, Herrmann Storck C, Theodose R, Olive C, Nicolas M, Hochedez P, Lamaury I, Zinini F, Brémont S, Landier A, Cassadou S, Rosine J, Picardeau M, Serovar diversity of pathogenic Leptospira circulating in the French West Indies, PLoS Negl Trop Dis 2013;7(3):e2114.
• 2013
  Bourhy P, Vray M, Picardeau M, Evaluation of an in-house ELISA using the intermediate species Leptospira fainei for diagnosis of leptospirosis, J. Med. Microbiol. 2013 Jun;62(Pt 6):822-7.
• 2012
  Lambert A, Takahashi N, Charon NW, Picardeau M, Chemotactic behavior of pathogenic and nonpathogenic Leptospira species, Appl. Environ. Microbiol. 2012 Dec;78(23):8467-9.
• 2012
  Lambert A, Picardeau M, Haake DA, Sermswan RW, Srikram A, Adler B, Murray GA, FlaA proteins in Leptospira interrogans are essential for motility and virulence but are not required for formation of the flagellum sheath, Infect. Immun. 2012 Jun;80(6):2019-25.
• 2012
  Slamti L, Picardeau M, Construction of a library of random mutants in the spirochete Leptospira biflexa using a mariner transposon, Methods Mol. Biol. 2012;859:169-76.
• 2011
  Slamti L, de Pedro MA, Guichet E, Picardeau M, Deciphering morphological determinants of the helix-shaped Leptospira, J. Bacteriol. 2011 Nov;193(22):6266-75.
• 2011
  Lourdault K, Cerqueira GM, Wunder EA, Picardeau M, Inactivation of clpB in the pathogen Leptospira interrogans reduces virulence and resistance to stress conditions, Infect. Immun. 2011 Sep;79(9):3711-7.
• 2011
  Figueira CP, Croda J, Choy HA, Haake DA, Reis MG, Ko AI, Picardeau M, Heterologous expression of pathogen-specific genes ligA and ligB in the saprophyte Leptospira biflexa confers enhanced adhesion to cultured cells and fibronectin, BMC Microbiol. 2011;11:129.
• 2011
  Bourhy P, Bremont S, Zinini F, Giry C, Picardeau M, Comparison of real-time PCR assays for detection of pathogenic Leptospira spp. in blood and identification of variations in target sequences, J. Clin. Microbiol. 2011 Jun;49(6):2154-60.
• 2010
  Aviat F, Slamti L, Cerqueira GM, Lourdault K, Picardeau M, Expanding the genetic toolbox for Leptospira species by generation of fluorescent bacteria, Appl. Environ. Microbiol. 2010 Dec;76(24):8135-42.
• 2010
  Bourhy P, Collet L, Clément S, Huerre M, Ave P, Giry C, Pettinelli F, Picardeau M, Isolation and characterization of new Leptospira genotypes from patients in Mayotte (Indian Ocean), PLoS Negl Trop Dis 2010;4(6):e724.
• 2010
  Poggi D, Oliveira de Giuseppe P, Picardeau M, Antibiotic resistance markers for genetic manipulations of Leptospira spp, Appl. Environ. Microbiol. 2010 Jul;76(14):4882-5.
• 2009
  Picardeau M, Transposition of fly mariner elements into bacteria as a genetic tool for mutagenesis, Genetica 2010 May;138(5):551-8.
• 2009
  Lourdault K, Aviat F, Picardeau M, Use of quantitative real-time PCR for studying the dissemination of Leptospira interrogans in the guinea pig infection model of leptospirosis, J. Med. Microbiol. 2009 May;58(Pt 5):648-55.
• 2008
  Ristow P, Bourhy P, Kerneis S, Schmitt C, Prevost MC, Lilenbaum W, Picardeau M, Biofilm formation by saprophytic and pathogenic leptospires, Microbiology (Reading, Engl.) 2008 May;154(Pt 5):1309-17.
• 2008
  Picardeau M, Bulach DM, Bouchier C, Zuerner RL, Zidane N, Wilson PJ, Creno S, Kuczek ES, Bommezzadri S, Davis JC, McGrath A, Johnson MJ, Boursaux-Eude C, Seemann T, Rouy Z, Coppel RL, Rood JI, Lajus A, Davies JK, Médigue C, Adler B, Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis, PLoS ONE 2008;3(2):e1607.
• 2008
  Louvel H, Betton JM, Picardeau M, Heme rescues a two-component system Leptospira biflexa mutant, BMC Microbiol. 2008;8:25.
• 2007
  Picardeau M, Conjugative transfer between Escherichia coli and Leptospira spp. as a new genetic tool, Appl. Environ. Microbiol. 2008 Jan;74(1):319-22.
• 2007
  Ristow P, Bourhy P, da Cruz McBride FW, Figueira CP, Huerre M, Ave P, Girons IS, Ko AI, Picardeau M, The OmpA-like protein Loa22 is essential for leptospiral virulence, PLoS Pathog. 2007 Jul;3(7):e97.
• 2007
  Louvel H, Picardeau M, Genetic manipulation of Leptospira biflexa, Curr Protoc Microbiol 2007 Jun;Chapter 12:Unit 12E.4.
• 2006
  Bourhy P, Salaün L, Lajus A, Médigue C, Boursaux-Eude C, Picardeau M, A genomic island of the pathogen Leptospira interrogans serovar Lai can excise from its chromosome, Infect. Immun. 2007 Feb;75(2):677-83.
• 2006
  Salaün L, Mérien F, Gurianova S, Baranton G, Picardeau M, Application of multilocus variable-number tandem-repeat analysis for molecular typing of the agent of leptospirosis, J. Clin. Microbiol. 2006 Nov;44(11):3954-62.
• 2006
  Mazouni K, Pehau-Arnaudet G, England P, Bourhy P, Saint Girons I, Picardeau M, The scc spirochetal coiled-coil protein forms helix-like filaments and binds to nucleic acids generating nucleoprotein structures, J. Bacteriol. 2006 Jan;188(2):469-76.
• 2005
  Bourhy P, Frangeul L, Couvé E, Glaser P, Saint Girons I, Picardeau M, Complete nucleotide sequence of the LE1 prophage from the spirochete Leptospira biflexa and characterization of its replication and partition functions, J. Bacteriol. 2005 Jun;187(12):3931-40.
• 2005
  Bourhy P, Louvel H, Saint Girons I, Picardeau M, Random insertional mutagenesis of Leptospira interrogans, the agent of leptospirosis, using a mariner transposon, J. Bacteriol. 2005 May;187(9):3255-8.
• 2005
  Louvel H, Saint Girons I, Picardeau M, Isolation and characterization of FecA- and FeoB-mediated iron acquisition systems of the spirochete Leptospira biflexa by random insertional mutagenesis, J. Bacteriol. 2005 May;187(9):3249-54.
• 2003
  Picardeau M, Le Dantec C, Richard GF, Saint Girons I, The spirochetal chpK-chromosomal toxin-antitoxin locus induces growth inhibition of yeast and mycobacteria, FEMS Microbiol. Lett. 2003 Dec;229(2):277-81.
• 2003
  Picardeau M, Bauby H, Saint Girons I, Genetic evidence for the existence of two pathways for the biosynthesis of methionine in the Leptospira spp, FEMS Microbiol. Lett. 2003 Aug;225(2):257-62.
• 2003
  Guégan R, Camadro JM, Saint Girons I, Picardeau M, Leptospira spp. possess a complete haem biosynthetic pathway and are able to use exogenous haem sources, Mol. Microbiol. 2003 Aug;49(3):745-54.
• 2003
  Bauby H, Saint Girons I, Picardeau M, Construction and complementation of the first auxotrophic mutant in the spirochaete Leptospira meyeri, Microbiology (Reading, Engl.) 2003 Mar;149(Pt 3):689-93.
• 2002
  Tchamedeu Kameni AP, Couture-Tosi E, Saint-Girons I, Picardeau M, Inactivation of the spirochete recA gene results in a mutant with low viability and irregular nucleoid morphology, J. Bacteriol. 2002 Jan;184(2):452-8.