• 2024
  Morel C, Lemerle E, Tsai FC, Obadia T, Srivastava N, Marechal M, Salles A, Albert M, Stefani C, Benito Y, Vandenesch F, Lamaze C, Vassilopoulos S, Piel M, Bassereau P, Gonzalez-Rodriguez D, Leduc C, Lemichez E, Caveolin-1 protects endothelial cells from extensive expansion of transcellular tunnel by stiffening the plasma membrane., Elife 2024 Mar; 12(): .
• 2023
  Bergsten E, Mestivier D, Donnadieu F, Pedron T, Barau C, Meda LT, Mettouchi A, Lemichez E, Gorgette O, Chamaillard M, Vaysse A, Volant S, Doukani A, Sansonetti PJ, Sobhani I, Nigro G, Parvimonas micra, an oral pathobiont associated with colorectal cancer, epigenetically reprograms human colonocytes., Gut Microbes 2023 Dec; 15(2): 2265138.
• 2022
  Petracchini S, Hamaoui D, Doye A, Asnacios A, Fage F, Vitiello E, Balland M, Janel S, Lafont F, Gupta M, Ladoux B, Gilleron J, Maia TM, Impens F, Gagnoux-Palacios L, Daugaard M, Sorensen PH, Lemichez E, Mettouchi A, , Optineurin links Hace1-dependent Rac ubiquitylation to integrin-mediated mechanotransduction to control bacterial invasion and cell division., Nat Commun 2022 Oct; 13(1): 6059.
• 2022
  Tsoumtsa Meda LL, Landraud L, Petracchini S, Descorps-Declere S, Perthame E, Nahori MA, Ramirez Finn L, Ingersoll MA, Patiño-Navarrete R, Glaser P, Bonnet R, Dussurget O, Denamur E, Mettouchi A, Lemichez E, , The cnf1 gene is associated with an expanding Escherichia coli ST131 H30Rx/C2 subclade and confers a competitive advantage for gut colonization., Gut Microbes 2022 ; 14(1): 2121577.
• 2022
  Cottone G, Chiodo L, Maragliano L, Popoff MR, Rasetti-Escargueil C, Lemichez E, Malliavin TE, , In Silico Conformational Features of Botulinum Toxins A1 and E1 According to Intraluminal Acidification., Toxins (Basel) 2022 Sep; 14(9): .
• 2022
  Wu Y, Mahtal N, Paillares E, Swistak L, Sagadiev S, Acharya M, Demeret C, Werf SV, Guivel-Benhassine F, Schwartz O, Petracchini S, Mettouchi A, Caramelle L, Couvineau P, Thai R, Barbe P, Keck M, Brodin P, Machelart A, Sencio V, Trottein F, Sachse M, Chicanne G, Payrastre B, Ville F, Kreis V, Popoff MR, Johannes L, Cintrat JC, Barbier J, Gillet D, Lemichez E, , C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus., iScience 2022 Jul; 25(7): 104537.
• 2021
  Tsai MC, Fleuriot L, Janel S, Gonzalez-Rodriguez D, Morel C, Mettouchi A, Debayle D, Dallongeville S, Olivo-Marin JC, Antonny B, Lafont F, Lemichez E, Barelli H, , DHA-phospholipids control membrane fusion and transcellular tunnel dynamics., J Cell Sci 2021 Dec; (): .
• 2021
  Paillares E, Marechal M, Swistak L, Tsoumtsa Meda L, Lemichez E, Malliavin TE, , Conformational Insights into the Control of CNF1 Toxin Activity by Peptidyl-Prolyl Isomerization: A Molecular Dynamics Perspective., Int J Mol Sci 2021 Sep; 22(18): .
• 2021
  Brier S, Rasetti-Escargueil C, Wijkhuisen A, Simon S, Marechal M, Lemichez E, Popoff MR, , Characterization of a highly neutralizing single monoclonal antibody to botulinum neurotoxin type A., FASEB J 2021 May; 35(5): e21540.
• 2019
  Torrino S, Roustan FR, Kaminski L, Bertero T, Pisano S, Ambrosetti D, Dufies M, Uhler JP, Lemichez E, Mettouchi A, Gesson M, Laurent K, Gaggioli C, Michiels JF, Lamaze C, Bost F, Clavel S., UBTD1 is a mechano-regulator controlling cancer aggressiveness, EMBO Rep. 2019 Apr;20(4)..
• 2018
  Tsai FC, Bertin A, Bousquet H, Manzi J, Senju Y, Tsai MC, Picas L, Miserey-Lenkei S, Lappalainen P, Lemichez E, Coudrier E, Bassereau P, Ezrin enrichment on curved membranes requires a specific conformation or interaction with a curvature-sensitive partner, Elife 2018 Sep;7.
• 2018
  Rasetti-Escargueil C, Lemichez E, Popoff MR, Variability of Botulinum Toxins: Challenges and Opportunities for the Future, Toxins (Basel) 2018 Sep;10(9).
• 2018
  Popoff MR, Botulinum Neurotoxins: Still a Privilege of Clostridia?, Cell Host Microbe 2018 02;23(2):145-146.
• 2018
  Bourdoulous S, Lemichez E, Decoding glycan recognition by bacterial toxins, Nat Microbiol 2018 Feb;3(2):124-126.
• 2018
  Acosta MI, Urbach S, Doye A, Ng YW, Boudeau J, Mettouchi A, Debant A, Manser E, Visvikis O, Lemichez E, Group-I PAKs-mediated phosphorylation of HACE1 at serine 385 regulates its oligomerization state and Rac1 ubiquitination, Sci Rep 2018 Jan;8(1):1410.
• 2018
  Mahtal N, Brewee C, Pichard S, Visvikis O, Cintrat JC, Barbier J, Lemichez E, Gillet D, , Screening of a Drug Library Identifies Inhibitors of Cell Intoxication by CNF1., ChemMedChem 2018 04; 13(7): 754-761.
• 2018
  Popoff MR, “Bacterial Toxins” Section in the Journal Toxins: A Fantastic Multidisciplinary Interplay between Bacterial Pathogenicity Mechanisms, Physiological Processes, Genomic Evolution, and Subsequent Development of Identification Methods, Efficient Treatment, and Prevention of Toxigenic Bacteria, Toxins (Basel) 2018 Jan;10(1).
• 2017
  Ng WP, Webster KD, Stefani C, Schmid EM, Lemichez E, Bassereau P, Fletcher DA, Force-induced transcellular tunnel formation in endothelial cells, Mol. Biol. Cell 2017 Aug;.
• 2017
  Stefani C, Gonzalez-Rodriguez D, Senju Y, Doye A, Efimova N, Janel S, Lipuma J, Tsai MC, Hamaoui D, Maddugoda MP, Cochet-Escartin O, Prévost C, Lafont F, Svitkina T, Lappalainen P, Bassereau P, Lemichez E, Ezrin enhances line tension along transcellular tunnel edges via NMIIa driven actomyosin cable formation, Nat Commun 2017 Jun;8:15839.
• 2017
  Ernst K, Schmid J, Beck M, Hägele M, Hohwieler M, Hauff P, Ückert AK, Anastasia A, Fauler M, Jank T, Aktories K, Popoff MR, Schiene-Fischer C, Kleger A, Müller M, Frick M, Barth H, Hsp70 facilitates trans-membrane transport of bacterial ADP-ribosylating toxins into the cytosol of mammalian cells, Sci Rep 2017 Jun;7(1):2724.
• 2017
  Bouillot S, Munro P, Gallet B, Reboud E, Cretin F, Golovkine G, Schoehn G, Attrée I, Lemichez E, Huber P, Pseudomonas aeruginosa Exolysin promotes bacterial growth in lungs, alveolar damage and bacterial dissemination, Sci Rep 2017 May;7(1):2120.
• 2017
  Torre C, Abnave P, Tsoumtsa LL, Mottola G, Lepolard C, Trouplin V, Gimenez G, Desrousseaux J, Gempp S, Levasseur A, Padovani L, Lemichez E, Ghigo E, Staphylococcus aureus Promotes Smed-PGRP-2/Smed-setd8-1 Methyltransferase Signalling in Planarian Neoblasts to Sensitize Anti-bacterial Gene Responses During Re-infection, EBioMedicine 2017 Jun;20:150-160.
• 2017
  Andrio E, Lotte R, Hamaoui D, Cherfils J, Doye A, Daugaard M, Sorensen PH, Bost F, Ruimy R, Mettouchi A, Lemichez E, Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation, Sci Rep 2017 Mar;7:44779.
• 2017
  Ngba Essebe C, Visvikis O, Fines-Guyon M, Vergne A, Cattoir V, Lecoustumier A, Lemichez E, Sotto A, Lavigne JP, Dunyach-Remy C, Decrease of Staphylococcus aureus Virulence by Helcococcus kunzii in a Caenorhabditis elegans Model, Front Cell Infect Microbiol 2017;7:77.
• 2017
  Connan C, Voillequin M, Chavez CV, Mazuet C, Leveque C, Vitry S, Vandewalle A, Popoff MR, Botulinum neurotoxin type B uses a distinct entry pathway mediated by CDC42 into intestinal cells versus neuronal cells, Cell. Microbiol. 2017 Mar;.
• 2017
  Peck MW, Smith TJ, Anniballi F, Austin JW, Bano L, Bradshaw M, Cuervo P, Cheng LW, Derman Y, Dorner BG, Fisher A, Hill KK, Kalb SR, Korkeala H, Lindström M, Lista F, Lúquez C, Mazuet C, Pirazzini M, Popoff MR, Rossetto O, Rummel A, Sesardic D, Singh BR, Stringer SC, Historical Perspectives and Guidelines for Botulinum Neurotoxin Subtype Nomenclature, Toxins (Basel) 2017 Jan;9(1).
• 2017
  Lemichez E, New Aspects on Bacterial Effectors Targeting Rho GTPases, Curr. Top. Microbiol. Immunol. 2017;399:155-174.
• 2016
  Miethe S, Mazuet C, Liu Y, Tierney R, Rasetti-Escargueil C, Avril A, Frenzel A, Thullier P, Pelat T, Urbain R, Fontayne A, Sesardic D, Hust M, Popoff MR, Development of Germline-Humanized Antibodies Neutralizing Botulinum Neurotoxin A and B, PLoS ONE 2016;11(8):e0161446.
• 2016
  Lotte R, Lotte L, Bouvet P, Degand N, Bal A, Carles M, de Dompsure RB, Popoff MR, Ruimy R, First isolation of Clostridium indolis in a patient with chronic osteitis: a case report and literature review of human infections related to Clostridium saccharolyticum group species, Anaerobe 2016 Dec;42:44-49.
• 2016
  Mazuet C, Legeay C, Sautereau J, Ma L, Bouchier C, Bouvet P, Popoff MR, Diversity of Group I and II Clostridium botulinum Strains from France Including Recently Identified Subtypes, Genome Biol Evol 2016 06;8(6):1643-60.
• 2016
  Michel G, Ferrua B, Munro P, Boyer L, Mathal N, Gillet D, Marty P, Lemichez E, , Immunoadjuvant Properties of the Rho Activating Factor CNF1 in Prophylactic and Curative Vaccination against Leishmania infantum., PLoS One 2016 ; 11(6): e0156363.
• 2016
  Mazuet C, Yoon EJ, Boyer S, Pignier S, Blanc T, Doehring I, Meziane-Cherif D, Dumant-Forest C, Sautereau J, Legeay C, Bouvet P, Bouchier C, Quijano-Roy S, Pestel-Caron M, Courvalin P, Popoff MR, A penicillin- and metronidazole-resistant Clostridium botulinum strain responsible for an infant botulism case, Clin. Microbiol. Infect. 2016 Jul;22(7):644.e7-644.e12.
• 2016
  Schnell L, Mittler AK, Sadi M, Popoff MR, Schwan C, Aktories K, Mattarei A, Azarnia Tehran D, Montecucco C, Barth H, EGA Protects Mammalian Cells from Clostridium difficile CDT, Clostridium perfringens Iota Toxin and Clostridium botulinum C2 Toxin, Toxins (Basel) 2016 04;8(4):101.
• 2016
  Varela Chavez C, Haustant GM, Baron B, England P, Chenal A, Pauillac S, Blondel A, Popoff MR, The Tip of the Four N-Terminal α-Helices of Clostridium sordellii Lethal Toxin Contains the Interaction Site with Membrane Phosphatidylserine Facilitating Small GTPases Glucosylation, Toxins (Basel) 2016 Mar;8(4):90.
• 2016
  Zhang W, Wu KP, Sartori MA, Kamadurai HB, Ordureau A, Jiang C, Mercredi PY, Murchie R, Hu J, Persaud A, Mukherjee M, Li N, Doye A, Walker JR, Sheng Y, Hao Z, Li Y, Brown KR, Lemichez E, Chen J, Tong Y, Harper JW, Moffat J, Rotin D, Schulman BA, Sidhu SS, System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes, Mol. Cell 2016 Apr;62(1):121-36.
• 2016
  Ernst K, Liebscher M, Mathea S, Granzhan A, Schmid J, Popoff MR, Ihmels H, Barth H, Schiene-Fischer C, A novel Hsp70 inhibitor prevents cell intoxication with the actin ADP-ribosylating Clostridium perfringens iota toxin, Sci Rep 2016 Feb;6:20301.
• 2016
  Charles-Orszag A, Lemichez E, Tran Van Nhieu G, Duménil G, Microbial pathogenesis meets biomechanics, Curr. Opin. Cell Biol. 2016 Feb;38:31-7.
• 2016
  Connan C, Varela-Chavez C, Mazuet C, Molgó J, Haustant GM, Disson O, Lecuit M, Vandewalle A, Popoff MR, , Translocation and dissemination to target neurons of botulinum neurotoxin type B in the mouse intestinal wall., Cell Microbiol 2016 Feb; 18(2): 282-301.
• 2016
  Tréhard H, Poujol I, Mazuet C, Blanc Q, Gillet Y, Rossignol F, Popoff MR, Jourdan Da Silva N, A cluster of three cases of botulism due to Clostridium baratii type F, France, August 2015, Euro Surveill. 2016;21(4).
• 2015
  Rolando M, Stefani C, Doye A, Acosta MI, Visvikis O, Yevick HG, Buchrieser C, Mettouchi A, Bassereau P, Lemichez E, , Contractile actin cables induced by Bacillus anthracis lethal toxin depend on the histone acetylation machinery., Cytoskeleton (Hoboken) 2015 Oct; 72(10): 542-56.
• 2015
  Knapp O, Benz R, Popoff MR, Pore-forming activity of clostridial binary toxins, Biochim. Biophys. Acta 2016 Mar;1858(3):512-25.
• 2012
  Beitzinger C, Stefani C, Kronhardt A, Rolando M, Flatau G, Lemichez E, Benz R, Role of N-terminal His6-Tags in binding and efficient translocation of polypeptides into cells using anthrax protective antigen (PA), PLoS ONE 2012;7(10):e46964.
• 2011
  Kronhardt A, Rolando M, Beitzinger C, Stefani C, Leuber M, Flatau G, Popoff MR, Benz R, Lemichez E, Cross-reactivity of anthrax and C2 toxin: protective antigen promotes the uptake of botulinum C2I toxin into human endothelial cells, PLoS ONE 2011;6(8):e23133.
• 2011
  Visvikis O, Boyer L, Torrino S, Doye A, Lemonnier M, Lorès P, Rolando M, Flatau G, Mettouchi A, Bouvard D, Veiga E, Gacon G, Cossart P, Lemichez E, Escherichia coli producing CNF1 toxin hijacks Tollip to trigger Rac1-dependent cell invasion, Traffic 2011 May;12(5):579-90.
• 2010
  Rolando M, Stefani C, Flatau G, Auberger P, Mettouchi A, Mhlanga M, Rapp U, Galmiche A, Lemichez E, Transcriptome dysregulation by anthrax lethal toxin plays a key role in induction of human endothelial cell cytotoxicity, Cell. Microbiol. 2010 Jul;12(7):891-905.
• 2009
  Rolando M, Munro P, Stefani C, Auberger P, Flatau G, Lemichez E, Injection of Staphylococcus aureus EDIN by the Bacillus anthracis protective antigen machinery induces vascular permeability, Infect. Immun. 2009 Sep;77(9):3596-601.
• 2008
  Galmiche A, Fueller J, Santel A, Krohne G, Wittig I, Doye A, Rolando M, Flatau G, Lemichez E, Rapp UR, Isoform-specific interaction of C-RAF with mitochondria, J. Biol. Chem. 2008 May;283(21):14857-66.
• 2006
  Boyer L, Doye A, Rolando M, Flatau G, Munro P, Gounon P, Clément R, Pulcini C, Popoff MR, Mettouchi A, Landraud L, Dussurget O, Lemichez E, , Induction of transient macroapertures in endothelial cells through RhoA inhibition by Staphylococcus aureus factors., J Cell Biol 2006 Jun; 173(5): 809-19.