• 2025
  Antonaru LA, Rad-Menéndez C, Mbedi S, Sparmann S, Pope M, Oliver T, Wu S, Green DH, Gugger M, Nürnberg DJ, Evolution of far-red light photoacclimation in cyanobacteria., Curr Biol 2025 May; (): .
• 2025
  Apolline Bruley, Juliette Gaëtan, Muriel Gugger, Claire Pancrace, Maxime Millet, Geoffroy Gaschignard, Manuela Dezi, Jean-François Humbert, Julie Leloup, Fériel Skouri-Panet, Isabelle Callebaut, Karim Benzerara, Elodie Duprat, Diel changes in the expression of a marker gene and candidate genes for intracellular amorphous CaCO3 biomineralization in Microcystis, Peer Community Journal, 2025, 5, pp.e18. ⟨10.24072/pcjournal.516⟩.
• 2025
  Vagstad AL, Lakis E, Csizi KS, Walls W, Richter D, Soo Lee K, Stocker R, Gugger M, Broderick WE, Broderick JB, Reiher M, Piel J, Mechanistic Insights Into Post-Translational α-Keto-β-Amino Acid Formation by a Radical S-Adenosyl Methionine Peptide Splicease., Angew Chem Int Ed Engl 2025 Feb; 64(6): e202418054.
• 2025
  Saraf A, Blondet E, Boullié A, Criscuolo A, Gugger M, Insight on the heterocyte patterning and the proheterocyte division in the toxic cyanobacterium Kaarinaea lacus gen. nov., sp. nov., and its genomic potential for natural products., Harmful Algae 2025 Feb; 142(): 102792.
• 2024
  Hubrich F, Kandy SK, Chepkirui C, Padhi C, Mordhorst S, Moosmann P, Zhu T, Gugger M, Chekan JR, Piel J, Ribosomal peptides with polycyclic isoprenoid moieties., Chem 2024 Oct; 10(10): 3224-3242.
• 2023
  Shishido TK, Delbaje E, Wahlsten M, Vuori I, Jokela J, Gugger M, Fiore MF, Fewer DP, A cylindrospermopsin-producing cyanobacterium isolated from a microbial mat in the Baltic Sea, Toxicon 2023 Jul; 232: 107205.
• 2023
  Gugger M, Boullié A, Laurent T, Cyanotoxins and Other Bioactive Compounds from the Pasteur Cultures of Cyanobacteria (PCC), Toxins (Basel) 2023 Jun 9;15(6):388. .
• 2023
  Gaëtan J, Halary S, Millet M, Bernard C, Duval C, Hamlaoui S, Hecquet A, Gugger M, Marie B, Mehta N, Moreira D, Skouri-Panet F, Travert C, Duprat E, Leloup J, Benzerara K, Widespread formation of intracellular calcium carbonates by the bloom-forming cyanobacterium Microcystis, Environ Microbiol. 2023 Mar;25(3):751-765.
• 2022
  Kim Tiam S, Comte K, Dalle C, Delagrange M, Djediat C, Ducos B, Duval C, Feilke K, Hamlaoui S, Le Manach S, Setif P, Yéprémian C, Marie B, Kirilovsky D, Gugger M, Bernard C, , The success of the bloom-forming cyanobacteria Planktothrix: Genotypes variability supports variable responses to light and temperature stress., Harmful Algae 2022 Aug; 117: 102285.
• 2022
  Adomako M, Ernst D, Simkovsky R, Chao YY, Wang J, Fang M, Bouchier C, Lopez-Igual R, Mazel D, Gugger M, Golden SS, Comparative Genomics of Synechococcus elongatus Explains the Phenotypic Diversity of the Strains, mBio 2022 Jun; 13(3): e0086222.
• 2022
  Benzerara K, Duprat E, Bitard-Feildel T, Caumes G, Cassier-Chauvat C, Chauvat F, Dezi M, Diop SI, Gaschignard G, Görgen S, Gugger M, Lopez-Garcia P, Millet M, Skouri-Panet F, Moreira D, Callebault I, A new gene family diagnostic for intracellular biomineralization of amorphous Ca-carbonates by cyanobacteria, Genome Biol Evol 2022 Mar 2;14(3):evac026 .
• 2022
  Hubrich F, Bosch NM, Chepkirui C, Morinaka BI, Rust M, Gugger M, Robinson SL, Vagstad AL, Piel J, Ribosomally derived lipopeptides containing distinct fatty acyl moieties, PNAS January 18, 2022 119 (3) e2113120119; .
• 2021
  Purushothaman M, Sarkar S, Morita M, Gugger M, Schmidt EW, Morinaka BI, Genome-Mining-Based Discovery of the Cyclic Peptide Tolypamide and TolF, a Ser/Thr Forward O-Prenyltransferase, Angew Chem Int Ed Engl 2021 04; 60(15): 8460-8465.
• 2021
  Rimet F, Aylagas E, Borja A, Bouchez A, Canino A, Chauvin C, Chonova T, ....Gugger M....et al., Metadata standards and practical guidelines for specimen and DNA curation when building barcode reference libraries for aquatic life, Metabarcoding and Metagenomics 5: 17–33 .
• 2021
  Schorn MA, Verhoeven S, Ridder L, Huber F, ....Boullié A, .... Gugger M,..... et al., A community resource for paired genomic and metabolomic data mining, Nat Chem Biol 2021 Feb; 15.
• 2021
  Görgen S, Benzerara K, Skouri‑Panet F, Gugger M, Chauvat F, Cassier‑Chauvat C, The diversity of molecular mechanisms of carbonate biomineralization by bacteria, (2021) 1:2.
• 2020
  Nguyen TQN, Tooh YW, Sugiyama R, Nguyen TPD, Purushothaman M, Leow LC, Hanif K, Yong RHS, Agatha I, Winnerdy FR, Gugger M, Phan AT, Morinaka BI, , Post-translational formation of strained cyclophanes in bacteria, Nat Chem 2020 Nov;12(11):1042-1053.
• 2020
  Bösch N, Mariana B, Greczmiel U, Morinaka B, Gugger M, Oxenius A, Vagstad AL, Piel J, Landornamides, antiviral ornithine-containing ribosomal peptides discovered by proteusin mining, Angew. Chem. Int. Ed. Engl. 2020 Jul 13;59(29):11763-11768.
• 2020
  Bauersachs T, Gugger M, Schwark L, Heterocyte glycolipid diketones: A novel type of biomarker in theN2-fixing heterocytous cyanobacterium Microchaetesp, Organic Geochemistry Vol 141, March 2020, 103976.
• 2020
  Melo N, Wolff GH, Costa-da-Silva AL, Arribas R, Fernandez Triana M, Gugger M, Riffell JA, DeGennaro M, Stensmyr MC, Geosmin Attracts Aedes aegypti Mosquitoes to Oviposition Sites, Curr Biol. 2020 Jan 6;30(1):127-134.e5.
• 2020
  Brito Â, Vieira J, Vieira CP, Zhu T, Leão PN, Ramos V, Lu X, Vasconcelos VM, Gugger M, Tamagnini P, Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides, Front Microbiol 2020 ; 11(): 1527.
• 2019
  Li M, Calteau A, Semchonok DA, Witt TA, Nguyen JT, Sassoon N, Boekema EJ, Whitelegge J, Gugger M, Bruce BD, Physiological and evolutionary implications of tetrameric photosystem I in cyanobacteria, Nat Plants 2019 Dec;5(12):1309-1319.
• 2019
  Mattila A, Andsten RM, Jumppanen M, Assante M, Jokela J, Wahlsten M, Mikula KM, Sigindere C, Kwak DH, Gugger M, Koskela H, Sivonen K, Liu X, Yli-Kauhaluoma J, Iwai H, Fewer DP, Biosynthesis of the bis-prenylated alkaloids muscoride A and B, ACS Chem Biol. 2019 Dec 20;14(12):2683-2690.
• 2019
  Kim Tiam S, Comte K, Dalle C, Duval C, Pancrace C, Gugger M, Marie B, Yéprémian C, Bernard C, Development of a new extraction method based on high-intensity ultra-sonication to study RNA regulation of the filamentous cyanobacteria Planktothrix, PLoS ONE 2019;14(9):e0222029.
• 2019
  Kim Tiam S, Gugger M, Demay J, Le Manach S, Duval C, Bernard C, Marie B, Insights into the Diversity of Secondary Metabolites of Using a Biphasic Approach Combining Global Genomics and Metabolomics, Toxins (Basel). 2019 Aug 27;11(9). pii: E498.
• 2019
  De Wever A, Benzerara K, Coutaud M, Caumes G, Poinsot M, Skouri-Panet F, Laurent T, Duprat E, Gugger M, Evidence of high Ca uptake by cyanobacteria forming intracellular CaCO and impact on their growth, Geobiology. 2019 Nov;17(6):676-690.
• 2019
  Helfrich EJN, Ueoka R, Dolev A, Rust M, Meoded RA, Bhushan A, Califano G, Costa R, Gugger M, Steinbeck C, Moreno P, Piel J, Automated structure prediction of trans-acyltransferase polyketide synthase products, Nat. Chem. Biol. 2019 July 15, 813-821.
• 2019
  Bauersachs T, Miller SR, Gugger M, Mudimu O, Friedl T, Schwark L, Heterocyte glycolipids indicate polyphyly of stigonematalean cyanobacteria, Phytochemistry 2019 Jul;166:112059.
• 2019
  Dilsizoglu Senol A, Pepe A, Grudina C, Sassoon N, Reiko U, Bousset L, Melki R, Piel J, Gugger M, Zurzolo C, Effect of tolytoxin on tunneling nanotube formation and function, Sci Rep 2019 Apr;9(1):5741.
• 2018
  Gugger M., Cyanobactéries, de l’oxygénation terrestre au substances naturelles, In Microbiodiversité, un nouveau regard, Laurent Palka Ed., Ch 10, pp. 255-274. Éditions Matériologiques.
• 2018
  Pancrace C, Ishida K, Briand E, Gatte Pichi D, Weiz AR, Guljamow A, Scalvenzi T, Sassoon N, Hertweck C, Dittmann E, Gugger M, A Unique Biosynthetic Pathway in Bloom-Forming Cyanobacterial Genus Microcystis Jointly Assembles Cytotoxic Aeruginoguanidines and Microguanidines, ACS Chem. Biol. 2019 Feb;4(1):67–75.
• 2018
  Moosmann P, Ueoka R, Gugger M, Piel J, Aranazoles: Extensively Chlorinated Nonribosomal Peptide-Polyketide Hybrids from the Cyanobacterium Fischerella sp. PCC 9339, Org. Lett. 2018 09;20(17):5238-5241.
• 2018
  Zhu T, Scalvenzi T, Sassoon N, Lu X, Gugger M, Terminal olefin profiles and phylogenetic analyses of olefin synthases in diversified cyanobacterial species, Appl. Environ. Microbiol. 2018 Jun;84(13):e00425-18.
• 2018
  Morinaka BI, Lakis E, Verest M, Helf MJ, Scalvenzi T, Vagstad AL, Sims J, Sunagawa S, Gugger M, Piel J, Natural noncanonical protein splicing yields products with diverse β-amino acid residues, Science 2018 02;359(6377):779-782.
• 2017
  Haande S, Jasser I, Gugger M, Hagman CHC, Wilmotte A, Ballot A., Isolation, Purification, and Cultivation of Toxigenic Cyanobacteria, 2017 Aug, chapter 3, pages 43-78. Wiley..
• 2017
  Pancrace C, Jokela J, Sassoon N, Ganneau C, Desnos-Ollivier M, Wahlsten M, Humisto A, Calteau A, Bay S, Fewer DP, Sivonen K, Gugger M, Rearranged Biosynthetic Gene Cluster and Synthesis of Hassallidin E in Planktothrix serta PCC 8927, ACS Chem Biol 2017 Jul; 12(7): 1796-1804.
• 2017
  Gugger M, Ledreux A, Toxines produites par les microalgues et cyanobactéries, In Risques microbiologiques alimentaires, Coll. Sciences et techniques agroalimentaires, Ch.32, pp 767-786.
• 2017
  Moosmann P, Ueoka R, Grauso L, Mangoni A, Morinaka BI, Gugger M, Piel J, Cyanobacterial ent-Sterol-Like Natural Products from a Deviated Ubiquinone Pathway, Angew Chem Int Ed Engl. 2017 Apr;56(18):4987-4990.
• 2017
  Pancrace C, Barny MA, Ueoka R, Calteau A, Scalvenzi T, Pédron J, Barbe V, Piel J, Humbert JF, Gugger M, Insights into the Planktothrix genus: Genomic and metabolic comparison of benthic and planktic strains, Sci Rep 2017 Jan;7:41181.
• 2017
  Pancrace C., Gugger M., Calteau A., Genomics of NRPS/PKS Biosynthetic Gene Clusters in Cyanobacteria, Cyanobacteria: Omics and Manipulation | Book edited Los Dimitri 2017 Jan;55-74.
• 2016
  Morinaka BI, Verest M, Freeman MF, Gugger M, Piel J, An Orthogonal D2 O-Based Induction System that Provides Insights into d-Amino Acid Pattern Formation by Radical S-Adenosylmethionine Peptide Epimerases, Angew. Chem. Int. Ed. Engl. 2017 Jan;56(3):762-766.
• 2016
  Berger C, Ba N, Gugger M, Bouvy M, Rusconi F, Couté A, Troussellier M, Bernard C, Seasonal dynamics and toxicity of Cylindrospermopsis raciborskii in Lake Guiers (Senegal, West Africa), FEMS Microbiol. Ecol. 2006 Sep;57(3):355-66.
• 2016
  Gonzalez-Esquer CR, Smarda J, Rippka R, Axen SD, Guglielmi G, Gugger M, Kerfeld CA, Cyanobacterial ultrastructure in light of genomic sequence data, Photosyn. Res. 2016 Aug;129(2):147-57.
• 2016
  Briand E, Bormans M, Gugger M, Dorrestein PC, Gerwick WH, Changes in secondary metabolic profiles of Microcystis aeruginosa strains in response to intraspecific interactions, Environ. Microbiol. 2016 Feb;18(2):384-400.
• 2016
  Beal J, Haddock-Angelli T, Gershater M, de Mora K, Lizarazo M, Hollenhorst J, Rettberg R,, Reproducibility of Fluorescent Expression from Engineered Biological Constructs in E. coli, PLoS ONE 2016;11(3):e0150182.
• 2015
  Dittmann E, Gugger M, Sivonen K, Fewer DP, Natural Product Biosynthetic Diversity and Comparative Genomics of the Cyanobacteria, Trends Microbiol. 2015 Oct;23(10):642-52.
• 2015
  Ueoka R, Uria AR, Reiter S, Mori T, Karbaum P, Peters EE, Helfrich EJ, Morinaka BI, Gugger M, Takeyama H, Matsunaga S, Piel J, Metabolic and evolutionary origin of actin-binding polyketides from diverse organisms, Nat. Chem. Biol. 2015 Sep;11(9):705-12.
• 2015
  Schirrmeister BE, Gugger M, Donoghue PC, Cyanobacteria and the Great Oxidation Event: evidence from genes and fossils, Palaeontology 2015 Sep;58(5):769-785.
• 2015
  Echenique-Subiabre I, Villeneuve A, Golubic S, Turquet J, Humbert JF, Gugger M, Influence of local and global environmental parameters on the composition of cyanobacterial mats in a tropical lagoon, Microb. Ecol. 2015 Feb;69(2):234-44.
• 2014
  Calteau A, Fewer DP, Latifi A, Coursin T, Laurent T, Jokela J, Kerfeld CA, Sivonen K, Piel J, Gugger M, Phylum-wide comparative genomics unravel the diversity of secondary metabolism in Cyanobacteria, BMC Genomics 2014;15:977.
• 2014
  Benzerara K, Skouri-Panet F, Li J, Férard C, Gugger M, Laurent T, Couradeau E, Ragon M, Cosmidis J, Menguy N, Margaret-Oliver I, Tavera R, López-García P, Moreira D, Intracellular Ca-carbonate biomineralization is widespread in cyanobacteria, Proc. Natl. Acad. Sci. U.S.A. 2014 Jul;111(30):10933-8.
• 2014
  Morinaka BI, Vagstad AL, Helf MJ, Gugger M, Kegler C, Freeman MF, Bode HB, Piel J, Radical S-adenosyl methionine epimerases: regioselective introduction of diverse D-amino acid patterns into peptide natural products, Angew. Chem. Int. Ed. Engl. 2014 Aug;53(32):8503-7.
• 2014
  Roué M, Gugger M, Golubic S, Amzil Z, Araoz R, Turquet J, Chinain M, Laurent D, Marine cyanotoxins potentially harmful to human health, Outstanding Marine Molecules: Chemistry, Biology, Analysis, eds La Barre S, Kornprobst JM (WILEY-Blackwell, Weinheim) chap. 01 pp. 3–22..
• 2013
  Baran R, Ivanova NN, Jose N, Garcia-Pichel F, Kyrpides NC, Gugger M, Northen TR, Functional genomics of novel secondary metabolites from diverse cyanobacteria using untargeted metabolomics, Mar Drugs 2013 Oct;11(10):3617-31.
• 2013
  Humbert JF, Barbe V, Latifi A, Gugger M, Calteau A, Coursin T, Lajus A, Castelli V, Oztas S, Samson G, Longin C, Medigue C, de Marsac NT, A tribute to disorder in the genome of the bloom-forming freshwater cyanobacterium Microcystis aeruginosa, PLoS ONE 2013;8(8):e70747.
• 2013
  Leikoski N, Liu L, Jokela J, Wahlsten M, Gugger M, Calteau A, Permi P, Kerfeld CA, Sivonen K, Fewer DP, Genome mining expands the chemical diversity of the cyanobactin family to include highly modified linear peptides, Chem. Biol. 2013 Aug;20(8):1033-43.
• 2013
  Shih PM, Wu D, Latifi A, Axen SD, Fewer DP, Talla E, Calteau A, Cai F, Tandeau de Marsac N, Rippka R, Herdman M, Sivonen K, Coursin T, Laurent T, Goodwin L, Nolan M, Davenport KW, Han CS, Rubin EM, Eisen JA, Woyke T, Gugger M, Kerfeld CA, Improving the coverage of the cyanobacterial phylum using diversity-driven genome sequencing, Proc. Natl. Acad. Sci. U.S.A. 2013 Jan;110(3):1053-8.
• 2013
  Dagan T, Roettger M, Stucken K, Landan G, Koch R, Major P, Gould SB, Goremykin VV, Rippka R, Tandeau de Marsac N, Gugger M, Lockhart PJ, Allen JF, Brune I, Maus I, Pühler A, Martin WF, Genomes of Stigonematalean cyanobacteria (subsection V) and the evolution of oxygenic photosynthesis from prokaryotes to plastids, Genome Biol Evol 2013;5(1):31-44.
• 2012
  Villeneuve A, Laurent D, Chinain M, Gugger M, Humbert JF, Molecular characterization of the diversity and potential toxicity of cyanobacterial mats in two tropical lagoons in the South Pacific Ocean (1), J Phycol 2012 Apr; 48(2): 275-84.
• 2011
  Rantala-Ylinen A, Känä S, Wang H, Rouhiainen L, Wahlsten M, Rizzi E, Berg K, Gugger M, Sivonen K, Anatoxin-a synthetase gene cluster of the cyanobacterium Anabaena sp. strain 37 and molecular methods to detect potential producers, Appl. Environ. Microbiol. 2011 Oct;77(20):7271-8.
• 2010
  Humbert JF, Quiblier C, Gugger M, Molecular approaches for monitoring potentially toxic marine and freshwater phytoplankton species, Anal Bioanal Chem 2010 Jul;397(5):1723-32.
• 2008
  Briand E, Gugger M, François JC, Bernard C, Humbert JF, Quiblier C, Temporal variations in the dynamics of potentially microcystin-producing strains in a bloom-forming Planktothrix agardhii (Cyanobacterium) population, Appl. Environ. Microbiol. 2008 Jun;74(12):3839-48.
• 2007
  Yéprémian C, Gugger MF, Briand E, Catherine A, Berger C, Quiblier C, Bernard C, Microcystin ecotypes in a perennial Planktothrix agardhii bloom, Water Res. 2007 Nov;41(19):4446-56.
• 2005
  Chaillan F, Gugger M, Saliot A, Couté A, Oudot J, Role of cyanobacteria in the biodegradation of crude oil by a tropical cyanobacterial mat, Chemosphere 2006 Mar;62(10):1574-82.
• 2005
  Gugger M, Lenoir S, Berger C, Ledreux A, Druart JC, Humbert JF, Guette C, Bernard C, First report in a river in France of the benthic cyanobacterium Phormidium favosum producing anatoxin-a associated with dog neurotoxicosis, Toxicon 2005 Jun;45(7):919-28.
• 2005
  Gugger M, Molica R, Le Berre B, Dufour P, Bernard C, Humbert JF, Genetic diversity of Cylindrospermopsis strains (cyanobacteria) isolated from four continents, Appl. Environ. Microbiol. 2005 Feb;71(2):1097-100.
• 2004
  Gugger MF, Hoffmann L, Polyphyly of true branching cyanobacteria (Stigonematales), Int. J. Syst. Evol. Microbiol. 2004 Mar;54(Pt 2):349-57.
• 2002
  Gugger M, Lyra C, Henriksen P, Couté A, Humbert JF, Sivonen K, Phylogenetic comparison of the cyanobacterial genera Anabaena and Aphanizomenon, Int. J. Syst. Evol. Microbiol. 2002 Sep;52(Pt 5):1867-80.
• 2002
  Gugger M, Lyra C, Suominen I, Tsitko I, Humbert JF, Salkinoja-Salonen MS, Sivonen K, Cellular fatty acids as chemotaxonomic markers of the genera Anabaena, Aphanizomenon, Microcystis, Nostoc and Planktothrix (cyanobacteria), Int. J. Syst. Evol. Microbiol. 2002 May;52(Pt 3):1007-15.
• 2001
  Laamanen MJ, Gugger MF, Lehtimäki JM, Haukka K, Sivonen K, Diversity of toxic and nontoxic nodularia isolates (cyanobacteria) and filaments from the Baltic Sea, Appl. Environ. Microbiol. 2001 Oct;67(10):4638-47.
• 2001
  Lyra C, Suomalainen S, Gugger M, Vezie C, Sundman P, Paulin L, Sivonen K, Molecular characterization of planktic cyanobacteria of Anabaena, Aphanizomenon, Microcystis and Planktothrix genera, Int. J. Syst. Evol. Microbiol. 2001 Mar;51(Pt 2):513-26.