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  • 2024
    Bruno F, Castelli G, Li B, Reale S, Carra E, Vitale F, Scibetta S, Calzolari M, Varani S, Ortalli M, Franceschini E, Gennari W, Rugna G, Späth GF, Genomic and epidemiological evidence for the emergence of a L. infantum/L. donovani hybrid with unusual epidemiology in northern Italy., mBio 2024 Jun; (): e0099524.
  • 2023
    Bussotti G, Li B, Pescher P, Vojtkova B, Louradour I, Pruzinova K, Sadlova J, Volf P, Späth GF, Leishmania allelic selection during experimental sand fly infection correlates with mutational signatures of oxidative DNA damage., Proc Natl Acad Sci U S A 2023 Mar; 120(10): e2220828120.
  • 2023
    Mano C, Kongkaew A, Tippawangkosol P, Somboon P, Roytrakul S, Pescher P, Späth GF, Uthaipibull C, Tantiworawit A, Siriyasatien P, Jariyapan N, Amphotericin B resistance correlates with increased fitness in vitro and in vivo in Leishmania (Mundinia) martiniquensis., Front Microbiol 2023 ; 14(): 1156061.
  • 2022
    Villares M, Lourenço N, Berthelet J, Lamotte S, Regad L, Medjkane S, Prina E, Rodrigues-Lima F, Späth GF, Weitzman JB, Trifloxystrobin blocks the growth of Theileria parasites and is a promising drug to treat Buparvaquone resistance., Commun Biol 2022 Nov; 5(1): 1253.
  • 2022
    Bruno F, Vitale F, La Russa F, Reale S, Späth GF, Oliveri E, Gargano V, Valenza V, Facciponte F, Giardina S, Marino G, Galante A, Castelli G, , Retrospective Analysis of Leishmaniasis in Sicily (Italy) from 2013 to 2021: One-Health Impact and Future Control Strategies., Microorganisms 2022 Aug; 10(9): .
  • 2022
    Di Bello E, Noce B, Fioravanti R, Zwergel C, Valente S, Rotili D, Fianco G, Trisciuoglio D, Mourão MM, Sales P, Lamotte S, Prina E, Späth GF, Häberli C, Keiser J, Mai A, Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni., ACS Infect Dis 2022 Jul; 8(7): 1356-1366.
  • 2022
    Lecoeur H, Prina E, Gutiérrez-Sanchez M, Späth GF, Going ballistic: Leishmania nuclear subversion of host cell plasticity., Trends Parasitol 2022 Mar; 38(3): 205-216.
  • 2022
    Piel L, Rajan KS, Bussotti G, Varet H, Legendre R, Proux C, Douché T, Giai-Gianetto Q, Chaze T, Cokelaer T, Vojtkova B, Gordon-Bar N, Doniger T, Cohen-Chalamish S, Rengaraj P, Besse C, Boland A, Sadlova J, Deleuze JF, Matondo M, Unger R, Volf P, Michaeli S, Pescher P, Späth GF, Experimental evolution links post-transcriptional regulation to Leishmania fitness gain., PLoS Pathog 2022 Mar; 18(3): e1010375.
  • 2021
    Bussotti G, Piel L, Pescher P, Domagalska MA, Rajan KS, Cohen-Chalamish S, Doniger T, Hiregange DG, Myler PJ, Unger R, Michaeli S, Späth GF, , Genome instability drives epistatic adaptation in the human pathogen Leishmania., Proc Natl Acad Sci U S A 2021 12; 118(51): .
  • 2021
    Späth GF, Bussotti G, , GIP: an open-source computational pipeline for mapping genomic instability from protists to cancer cells., Nucleic Acids Res 2021 Dec; (): .
  • 2021
    Formaglio P, Alabdullah M, Siokis A, Handschuh J, Sauerland I, Fu Y, Krone A, Gintschel P, Stettin J, Heyde S, Mohr J, Philipsen L, Schröder A, Robert PA, Zhao G, Khailaie S, Dudeck A, Bertrand J, Späth GF, Kahlfuß S, Bousso P, Schraven B, Huehn J, Binder S, Meyer-Hermann M, Müller AJ, Nitric oxide controls proliferation of Leishmania major by inhibiting the recruitment of permissive host cells., Immunity 2021 Dec; 54(12): 2724-2739.e10.
  • 2021
    Beniklef R, Aoun K, Boudrissa K, Ben Abid M, Cherif K, Aissi W, Benrekta S, Boubidi SC, Späth GF, Bouratbine A, Sereno D, Harrat Z, , Cutaneous Leishmaniasis in Algeria; Highlight on the Focus of M’Sila., Microorganisms 2021 Apr; 9(5): .
  • 2021
    Schwabl P, Boité MC, Bussotti G, Jacobs A, Andersson B, Moreira O, Freitas-Mesquita AL, Meyer-Fernandes JR, Telleria EL, Traub-Csekö Y, Vaselek S, Leštinová T, Volf P, Morgado FN, Porrozzi R, Llewellyn M, Späth GF, Cupolillo E, , Colonization and genetic diversification processes of Leishmania infantum in the Americas., Commun Biol 2021 01; 4(1): 139.
  • 2021
    Bazin MA, Cojean S, Pagniez F, Bernadat G, Cavé C, Ourliac-Garnier I, Nourrisson MR, Morgado C, Picot C, Leclercq O, Baratte B, Robert T, Späth GF, Rachidi N, Bach S, Loiseau PM, Le Pape P, Marchand P, , In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition., Eur J Med Chem 2021 Jan; 210(): 112956.
  • 2021
    Rachidi N, Knippschild U, Späth GF, , Dangerous Duplicity: The Dual Functions of Casein Kinase 1 in Parasite Biology and Host Subversion., Front Cell Infect Microbiol 2021 ; 11(): 655700.
  • 2021
    Smirlis D, Dingli F, Sabatet V, Roth A, Knippschild U, Loew D, Späth GF, Rachidi N, , Identification of the Host Substratome of Leishmania-Secreted Casein Kinase 1 Using a SILAC-Based Quantitative Mass Spectrometry Assay., Front Cell Dev Biol 2021 ; 9(): 800098.
  • 2020
    Andrade JM, Gonçalves LO, Liarte DB, Lima DA, Guimarães FG, de Melo Resende D, Santi AMM, de Oliveira LM, Velloso JPL, Delfino RG, Pescher P, Späth GF, Ruiz JC, Murta SMF, , Comparative transcriptomic analysis of antimony resistant and susceptible Leishmania infantum lines., Parasit Vectors 2020 Nov; 13(1): 600.
  • 2020
    Bussotti G, Benkahla A, Jeddi F, Souiaï O, Aoun K, Späth GF, Bouratbine A, , Nuclear and mitochondrial genome sequencing of North-African Leishmania infantum isolates from cured and relapsed visceral leishmaniasis patients reveals variations correlating with geography and phenotype., Microb Genom 2020 10; 6(10): .
  • 2020
    Rosazza T, Lecoeur H, Blisnick T, Moya-Nilges M, Pescher P, Bastin P, Prina E, Späth GF, , Dynamic imaging reveals surface exposure of virulent Leishmania amastigotes during pyroptosis of infected macrophages., J Cell Sci 2020 06; 134(5): .
  • 2020
    Baek KH, Piel L, Rosazza T, Prina E, Späth GF, No JH, , Infectivity and Drug Susceptibility Profiling of Different Leishmania-Host Cell Combinations., Pathogens 2020 May; 9(5): .
  • 2020
    Rocha VPC, Dacher M, Young SA, Kolokousi F, Efstathiou A, Späth GF, Soares MBP, Smirlis D, , Leishmania dual-specificity tyrosine-regulated kinase 1 (DYRK1) is required for sustaining Leishmania stationary phase phenotype., Mol Microbiol 2020 05; 113(5): 983-1002.
  • 2020
    Smirlis D, Dingli F, Pescher P, Prina E, Loew D, Rachidi N, Späth GF, , SILAC-based quantitative proteomics reveals pleiotropic, phenotypic modulation in primary murine macrophages infected with the protozoan pathogen Leishmania donovani., J Proteomics 2020 02; 213(): 103617.
  • 2020
    Lecoeur H, Prina E, Rosazza T, Kokou K, N'Diaye P, Aulner N, Varet H, Bussotti G, Xing Y, Milon G, Weil R, Meng G, Späth GF, Targeting Macrophage Histone H3 Modification as a Leishmania Strategy to Dampen the NF-κB/NLRP3-Mediated Inflammatory Response., Cell Rep 2020 Feb; 30(6): 1870-1882.e4.
  • 2020
    Lecoeur H, Rosazza T, Kokou K, Varet H, Coppée JY, Lari A, Commère PH, Weil R, Meng G, Milon G, Späth GF, Prina E, , Leishmania amazonensis Subverts the Transcription Factor Landscape in Dendritic Cells to Avoid Inflammasome Activation and Stall Maturation., Front Immunol 2020 ; 11(): 1098.
  • 2019
    Boité MC, Späth GF, Bussotti G, Porrozzi R, Morgado FN, Llewellyn M, Schwabl P, Cupolillo E, , Trans-Atlantic Spill Over: Deconstructing the Ecological Adaptation of Leishmania infantum in the Americas., Genes (Basel) 2019 12; 11(1): .
  • 2019
    Lamotte S, Aulner N, Späth GF, Prina E, , Author Correction: Discovery of novel hit compounds with broad activity against visceral and cutaneous Leishmania species by comparative phenotypic screening., Sci Rep 2019 Jul; 9(1): 10148.
  • 2019
    Hombach-Barrigah A, Bartsch K, Smirlis D, Rosenqvist H, MacDonald A, Dingli F, Loew D, Späth GF, Rachidi N, Wiese M, Clos J, , Leishmania donovani 90 kD Heat Shock Protein – Impact of Phosphosites on Parasite Fitness, Infectivity and Casein Kinase Affinity., Sci Rep 2019 03; 9(1): 5074.
  • 2019
    Rao SPS, Barrett MP, Dranoff G, Faraday CJ, Gimpelewicz CR, Hailu A, Jones CL, Kelly JM, Lazdins-Helds JK, Mäser P, Mengel J, Mottram JC, Mowbray CE, Sacks DL, Scott P, Späth GF, Tarleton RL, Spector JM, Diagana TT, , Drug Discovery for Kinetoplastid Diseases: Future Directions., ACS Infect Dis 2019 02; 5(2): 152-157.
  • 2019
    Lamotte S, Aulner N, Späth GF, Prina E, , Discovery of novel hit compounds with broad activity against visceral and cutaneous Leishmania species by comparative phenotypic screening., Sci Rep 2019 01; 9(1): 438.
  • 2018
    Bussotti G, Gouzelou E, Côrtes Boité M, Kherachi I, Harrat Z, Eddaikra N, Mottram JC, Antoniou M, Christodoulou V, Bali A, Guerfali FZ, Laouini D, Mukhtar M, Dumetz F, Dujardin JC, Smirlis D, Lechat P, Pescher P, El Hamouchi A, Lemrani M, Chicharro C, Llanes-Acevedo IP, Botana L, Cruz I, Moreno J, Jeddi F, Aoun K, Bouratbine A, Cupolillo E, Späth GF, , Leishmania Genome Dynamics during Environmental Adaptation Reveal Strain-Specific Differences in Gene Copy Number Variation, Karyotype Instability, and Telomeric Amplification., mBio 2018 11; 9(6): .
  • 2018
    Liburkin-Dan T, Schlisselberg D, Fischer-Weinberger R, Pescher P, Inbar E, Ephros M, Rentsch D, Späth GF, Zilberstein D, Stage-specific expression of the proline-alanine transporter in the human pathogen Leishmania, Mol. Biochem. Parasitol. 2018 06;222:1-5.
  • 2018
    Piel L, Pescher P, Späth GF, , Reverse Epidemiology: An Experimental Framework to Drive Leishmania Biomarker Discovery in situ by Functional Genetic Screening Using Relevant Animal Models., Front Cell Infect Microbiol 2018 ; 8(): 325.
  • 2017
    Prieto Barja P, Pescher P, Bussotti G, Dumetz F, Imamura H, Kedra D, Domagalska M, Chaumeau V, Himmelbauer H, Pages M, Sterkers Y, Dujardin JC, Notredame C, Späth GF, Haplotype selection as an adaptive mechanism in the protozoan pathogen Leishmania donovani, Nat Ecol Evol 2017 Dec;1(12):1961-1969.
  • 2017
    Dumetz F, Imamura H, Sanders M, Seblova V, Myskova J, Pescher P, Vanaerschot M, Meehan CJ, Cuypers B, De Muylder G, Späth GF, Bussotti G, Vermeesch JR, Berriman M, Cotton JA, Volf P, Dujardin JC, Domagalska MA, Modulation of Aneuploidy in during Adaptation to Different and Environments and Its Impact on Gene Expression, mBio 2017 05;8(3).
  • 2017
    Bahrami F, Späth GF, Rafati S, Old World cutaneous leishmaniasis challenges in Morocco, Algeria, Tunisia and Iran (MATI): a collaborative attempt to combat the disease, Expert Rev Vaccines 2017 May;16(5):415-417.
  • 2016
    Chua MJ, Arnold MS, Xu W, Lancelot J, Lamotte S, Späth GF, Prina E, Pierce RJ, Fairlie DP, Skinner-Adams TS, Andrews KT, Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth, Int J Parasitol Drugs Drug Resist 2017 04;7(1):42-50.
  • 2016
    Bendjeddou LZ, Loaëc N, Villiers B, Prina E, Späth GF, Galons H, Meijer L, Oumata N, Exploration of the imidazo[1,2-b]pyridazine scaffold as a protein kinase inhibitor, Eur J Med Chem 2017 Jan;125:696-709.
  • 2016
    Drini S, Criscuolo A, Lechat P, Imamura H, Skalický T, Rachidi N, Lukeš J, Dujardin JC, Späth GF, , Species- and Strain-Specific Adaptation of the HSP70 Super Family in Pathogenic Trypanosomatids., Genome Biol Evol 2016 07; 8(6): 1980-95.
  • 2016
    Yau WL, Lambertz U, Colineau L, Pescher P, MacDonald A, Zander D, Retzlaff S, Eick J, Reiner NE, Clos J, Späth GF, Phenotypic Characterization of a Leishmania donovani Cyclophilin 40 Null Mutant, J. Eukaryot. Microbiol. 2016 11;63(6):823-833.
  • 2016
    Durieu E, Prina E, Leclercq O, Oumata N, Gaboriaud-Kolar N, Vougogiannopoulou K, Aulner N, Defontaine A, No JH, Ruchaud S, Skaltsounis AL, Galons H, Späth GF, Meijer L, Rachidi N, , From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity., Antimicrob Agents Chemother 2016 05; 60(5): 2822-33.
  • 2016
    Späth GF, Clos J, Joining forces: first application of a rapamycin-induced dimerizable Cre system for conditional null mutant analysis in Leishmania, Mol. Microbiol. 2016 06;100(6):923-7.
  • 2016
    Javed N, Xue G, Lu A, Xing Y, Iwakura Y, Xiao H, Lecoeur H, Späth GF, Meng G, Cross reactivity of S. aureus to murine cytokine assays: A source of discrepancy, Cytokine 2016 May;81:101-8.
  • 2015
    Casanova M, Gonzalez IJ, Sprissler C, Zalila H, Dacher M, Basmaciyan L, Späth GF, Azas N, Fasel N, Implication of different domains of the Leishmania major metacaspase in cell death and autophagy, Cell Death Dis 2015;6:e1933.
  • 2015
    Moreira DS, Pescher P, Laurent C, Lenormand P, Späth GF, Murta SM, Phosphoproteomic analysis of wild-type and antimony-resistant Leishmania braziliensis lines by 2D-DIGE technology, Proteomics 2015 May;.
  • 2015
    Späth GF, Drini S, Rachidi N, , A touch of Zen: post-translational regulation of the Leishmania stress response., Cell Microbiol 2015 May; 17(5): 632-8.
  • 2014
    Forestier CL, Späth GF, Prina E, Dasari S, Simultaneous multi-parametric analysis of Leishmania and of its hosting mammal cells: A high content imaging-based method enabling sound drug discovery process, Microb. Pathog. 2014 Oct;.
  • 2014
    Dacher M, Morales MA, Pescher P, Leclercq O, Rachidi N, Prina E, Cayla M, Descoteaux A, Späth GF, , Probing druggability and biological function of essential proteins in Leishmania combining facilitated null mutant and plasmid shuffle analyses., Mol Microbiol 2014 Jul; 93(1): 146-66.
  • 2014
    Yau WL, Pescher P, MacDonald A, Hem S, Zander D, Retzlaff S, Blisnick T, Rotureau B, Rosenqvist H, Wiese M, Bastin P, Clos J, Späth GF, The Leishmania donovani chaperone cyclophilin 40 is essential for intracellular infection independent of its stage-specific phosphorylation status, Mol. Microbiol. 2014 Jul;93(1):80-97.
  • 2014
    Tsigankov P, Gherardini PF, Helmer-Citterich M, Späth GF, Myler PJ, Zilberstein D, Regulation dynamics of Leishmania differentiation: deconvoluting signals and identifying phosphorylation trends, Mol. Cell Proteomics 2014 Jul;13(7):1787-99.
  • 2014
    Rachidi N, Taly JF, Durieu E, Leclercq O, Aulner N, Prina E, Pescher P, Notredame C, Meijer L, Späth GF, , Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection., Antimicrob Agents Chemother 2014 ; 58(3): 1501-15.
  • 2013
    Louzir H, Aoun K, Späth GF, Laouini D, Prina E, Victoir K, Bouratbine A, [Leishmania epidemiology, diagnosis, chemotherapy and vaccination approaches in the international network of Pasteur Institutes], Med Sci (Paris) 2013 Dec;29(12):1151-60.
  • 2013
    Müller AJ, Aeschlimann S, Olekhnovitch R, Dacher M, Späth GF, Bousso P, Photoconvertible pathogen labeling reveals nitric oxide control of Leishmania major infection in vivo via dampening of parasite metabolism, Cell Host Microbe 2013 Oct;14(4):460-7.
  • 2013
    Tsigankov P, Gherardini PF, Helmer-Citterich M, Späth GF, Zilberstein D, Phosphoproteomic analysis of differentiating Leishmania parasites reveals a unique stage-specific phosphorylation motif, J. Proteome Res. 2013 Jul;12(7):3405-12.
  • 2013
    Leclercq O, Bartho K, Duelsner E, von Kleist L, Gherardini PF, Palmeri A, Helmer-Citterich M, Baumgart S, Späth GF, , Enrichment of Leishmania donovani ATP-binding proteins using a staurosporine capture compound., J Proteomics 2013 Jun; 86(): 97-104.
  • 2012
    Foucher AL, Rachidi N, Gharbi S, Blisnick T, Bastin P, Pemberton IK, Späth GF, , Apoptotic marker expression in the absence of cell death in staurosporine-treated Leishmania donovani., Antimicrob Agents Chemother 2013 Mar; 57(3): 1252-61.
  • 2012
    Horjales S, Schmidt-Arras D, Limardo RR, Leclercq O, Obal G, Prina E, Turjanski AG, Späth GF, Buschiazzo A, , The crystal structure of the MAP kinase LmaMPK10 from Leishmania major reveals parasite-specific features and regulatory mechanisms., Structure 2012 Oct; 20(10): 1649-60.
  • 2012
    Müller AJ, Filipe-Santos O, Eberl G, Aebischer T, Späth GF, Bousso P, CD4+ T cells rely on a cytokine gradient to control intracellular pathogens beyond sites of antigen presentation, Immunity 2012 Jul;37(1):147-57.
  • 2011
    Palmeri A, Gherardini PF, Tsigankov P, Ausiello G, Späth GF, Zilberstein D, Helmer-Citterich M, PhosTryp: a phosphorylation site predictor specific for parasitic protozoa of the family trypanosomatidae, BMC Genomics 2011;12:614.
  • 2011
    Mani J, Güttinger A, Schimanski B, Heller M, Acosta-Serrano A, Pescher P, Späth G, Roditi I, Alba-domain proteins of Trypanosoma brucei are cytoplasmic RNA-binding proteins that interact with the translation machinery, PLoS ONE 2011;6(7):e22463.
  • 2011
    Pescher P, Blisnick T, Bastin P, Späth GF, Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation, Cell. Microbiol. 2011 Jul;13(7):978-91.
  • 2011
    Forestier CL, Machu C, Loussert C, Pescher P, Späth GF, Imaging host cell-Leishmania interaction dynamics implicates parasite motility, lysosome recruitment, and host cell wounding in the infection process, Cell Host Microbe 2011 Apr;9(4):319-30.
  • 2011
    Schmidt-Arras D, Leclercq O, Gherardini PF, Helmer-Citterich M, Faigle W, Loew D, Späth GF, , Adaptation of a 2D in-gel kinase assay to trace phosphotransferase activities in the human pathogen Leishmania donovani., J Proteomics 2011 Aug; 74(9): 1644-51.
  • 2010
    Hem S, Gherardini PF, Osorio y Fortéa J, Hourdel V, Morales MA, Watanabe R, Pescher P, Kuzyk MA, Smith D, Borchers CH, Zilberstein D, Helmer-Citterich M, Namane A, Späth GF, Identification of Leishmania-specific protein phosphorylation sites by LC-ESI-MS/MS and comparative genomics analyses, Proteomics 2010 Nov;10(21):3868-83.
  • 2010
    Foucher AL, Späth GF, Pemberton IK, Probing the dynamic nature of signalling pathways by IMAC and SELDI-tof MS, Arch. Physiol. Biochem. 2010 Oct-Dec;116(4-5):163-73.
  • 2010
    Yau WL, Blisnick T, Taly JF, Helmer-Citterich M, Schiene-Fischer C, Leclercq O, Li J, Schmidt-Arras D, Morales MA, Notredame C, Romo D, Bastin P, Späth GF, , Cyclosporin A treatment of Leishmania donovani reveals stage-specific functions of cyclophilins in parasite proliferation and viability., PLoS Negl Trop Dis 2010 Jun; 4(6): e729.
  • 2010
    Dujardin JC, González-Pacanowska D, Croft SL, Olesen OF, Späth GF, Collaborative actions in anti-trypanosomatid chemotherapy with partners from disease endemic areas, Trends Parasitol. 2010 Aug;26(8):395-403.
  • 2010
    Morales MA, Watanabe R, Dacher M, Chafey P, Osorio y Fortéa J, Scott DA, Beverley SM, Ommen G, Clos J, Hem S, Lenormand P, Rousselle JC, Namane A, Späth GF, Phosphoproteome dynamics reveal heat-shock protein complexes specific to the Leishmania donovani infectious stage, Proc. Natl. Acad. Sci. U.S.A. 2010 May;107(18):8381-6.
  • 2009
    Morales MA, Pescher P, Späth GF, Leishmania major MPK7 protein kinase activity inhibits intracellular growth of the pathogenic amastigote stage, Eukaryotic Cell 2010 Jan;9(1):22-30.
  • 2009
    Filipe-Santos O, Pescher P, Breart B, Lippuner C, Aebischer T, Glaichenhaus N, Späth GF, Bousso P, A dynamic map of antigen recognition by CD4 T cells at the site of Leishmania major infection, Cell Host Microbe 2009 Jul;6(1):23-33.
  • 2009
    Peduto L, Dulauroy S, Lochner M, Späth GF, Morales MA, Cumano A, Eberl G, Inflammation recapitulates the ontogeny of lymphoid stromal cells, J. Immunol. 2009 May;182(9):5789-99.
  • 2009
    Späth GF, Schlesinger P, Schreiber R, Beverley SM, A novel role for Stat1 in phagosome acidification and natural host resistance to intracellular infection by Leishmania major, PLoS Pathog. 2009 Apr;5(4):e1000381.
  • 2009
    Rotureau B, Morales MA, Bastin P, Späth GF, The flagellum-mitogen-activated protein kinase connection in Trypanosomatids: a key sensory role in parasite signalling and development?, Cell. Microbiol. 2009 May;11(5):710-8.
  • 2008
    Späth GF, McDowell MA, Beverley SM, Leishmania major intracellular survival is not altered in SHP-1 deficient mev or CD45-/- mice, Exp. Parasitol. 2008 Nov;120(3):275-9.
  • 2008
    Morales MA, Watanabe R, Laurent C, Lenormand P, Rousselle JC, Namane A, Späth GF, Phosphoproteomic analysis of Leishmania donovani pro- and amastigote stages, Proteomics 2008 Jan;8(2):350-63.
  • 2007
    Frevert U, Späth GF, Yee H, Exoerythrocytic development of Plasmodium gallinaceum in the White Leghorn chicken, Int. J. Parasitol. 2008 May;38(6):655-72.
  • 2007
    Morales MA, Renaud O, Faigle W, Shorte SL, Späth GF, Over-expression of Leishmania major MAP kinases reveals stage-specific induction of phosphotransferase activity, Int. J. Parasitol. 2007 Sep;37(11):1187-99.
  • 2004
    Amprey JL, Im JS, Turco SJ, Murray HW, Illarionov PA, Besra GS, Porcelli SA, Späth GF, A subset of liver NK T cells is activated during Leishmania donovani infection by CD1d-bound lipophosphoglycan, J. Exp. Med. 2004 Oct;200(7):895-904.
  • 2004
    Späth GF, Lye LF, Segawa H, Turco SJ, Beverley SM, Identification of a compensatory mutant (lpg2-REV) of Leishmania major able to survive as amastigotes within macrophages without LPG2-dependent glycoconjugates and its significance to virulence and immunization strategies, Infect. Immun. 2004 Jun;72(6):3622-7.
  • 2004
    Uzonna JE, Späth GF, Beverley SM, Scott P, Vaccination with phosphoglycan-deficient Leishmania major protects highly susceptible mice from virulent challenge without inducing a strong Th1 response, J. Immunol. 2004 Mar;172(6):3793-7.
  • 2004
    Amprey JL, Späth GF, Porcelli SA, Inhibition of CD1 expression in human dendritic cells during intracellular infection with Leishmania donovani, Infect. Immun. 2004 Jan;72(1):589-92.
  • 2003
    Späth GF, Lye LF, Segawa H, Sacks DL, Turco SJ, Beverley SM, Persistence without pathology in phosphoglycan-deficient Leishmania major, Science 2003 Aug;301(5637):1241-3.
  • 2003
    Späth GF, Garraway LA, Turco SJ, Beverley SM, The role(s) of lipophosphoglycan (LPG) in the establishment of Leishmania major infections in mammalian hosts, Proc. Natl. Acad. Sci. U.S.A. 2003 Aug;100(16):9536-41.
  • 2001
    Späth GF, Beverley SM, A lipophosphoglycan-independent method for isolation of infective Leishmania metacyclic promastigotes by density gradient centrifugation, Exp. Parasitol. 2001 Oct;99(2):97-103.
  • 2001
    Turco SJ, Späth GF, Beverley SM, Is lipophosphoglycan a virulence factor? A surprising diversity between Leishmania species, Trends Parasitol. 2001 May;17(5):223-6.
  • 2000
    Späth GF, Epstein L, Leader B, Singer SM, Avila HA, Turco SJ, Beverley SM, Lipophosphoglycan is a virulence factor distinct from related glycoconjugates in the protozoan parasite Leishmania major, Proc. Natl. Acad. Sci. U.S.A. 2000 Aug;97(16):9258-63.
  • 1999
    Horn C, Namane A, Pescher P, Rivière M, Romain F, Puzo G, Bârzu O, Marchal G, Decreased capacity of recombinant 45/47-kDa molecules (Apa) of Mycobacterium tuberculosis to stimulate T lymphocyte responses related to changes in their mannosylation pattern, J. Biol. Chem. 1999 Nov;274(45):32023-30.
  • 1999
    Romain F, Horn C, Pescher P, Namane A, Riviere M, Puzo G, Barzu O, Marchal G, Deglycosylation of the 45/47-kilodalton antigen complex of Mycobacterium tuberculosis decreases its capacity to elicit in vivo or in vitro cellular immune responses, Infect. Immun. 1999 Nov;67(11):5567-72.
  • 1998
    Späth GF, Weiss MC, Hepatocyte nuclear factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells, J. Cell Biol. 1998 Feb;140(4):935-46.
  • 1997
    Späth GF, Weiss MC, Hepatocyte nuclear factor 4 expression overcomes repression of the hepatic phenotype in dedifferentiated hepatoma cells, Mol. Cell. Biol. 1997 Apr;17(4):1913-22.
  • 1995
    Späth GF, Ramadori G, Rittner C, Schneider PM, Expression of the complement C8 genes during interleukin-6-mediated in vitro induction of the acute-phase response, Exp. Clin. Immunogenet. 1995;12(1):53-60.
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