-
2024Deep estimation of the intensity and timing of natural selection from ancient genomes., Mol Ecol Resour 2024 Aug; (): e14015.
-
2024MANOCCA: a robust and computationally efficient test of covariance in high-dimension multivariate omics data., Brief Bioinform 2024 May; 25(4): .
-
2024Smoking changes adaptive immunity with persistent effects., Nature 2024 Feb; 626(8000): 827-835.
-
2023Unveiling Candida albicans intestinal carriage in healthy volunteers: the role of micro- and mycobiota, diet, host genetics and immune response., Gut Microbes 2023 Dec; 15(2): 2287618.
-
2023Dissecting human population variation in single-cell responses to SARS-CoV-2, Nature, 2023, 53 (8), pp.e2250307. ⟨10.1038/s41586-023-06422-9⟩.
-
2023Unravelling the determinants of human health in French Polynesia: the MATAEA project., Front Epidemiol 2023 ; 3(): 1201038.
-
2022The immune factors driving DNA methylation variation in human blood., Nat Commun 2022 Oct; 13(1): 5895.
-
2022The genomic landscape of contemporary western Remote Oceanians., Curr Biol 2022 Sep; (): .
-
2022Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation., Cell Rep 2022 Jun; 39(13): 110989.
-
2022Human evolution: The unsealed fates of foragers and farmers., Curr Biol 2022 04; 32(8): R362-R365.
-
2022Integrative genetic and immune cell analysis of plasma proteins in healthy donors identifies novel associations involving primary immune deficiency genes., Genome Med 2022 Mar; 14(1): 28.
-
2022The genomic signatures of natural selection in admixed human populations., Am J Hum Genet 2022 Mar; (): .
-
2021Genomic insights into population history and biological adaptation in Oceania., Nature 2021 Apr; 592(7855): 583-589.
-
2021Human ancient DNA analyses reveal the high burden of tuberculosis in Europeans over the last 2,000 years., Am J Hum Genet 2021 Mar; 108(3): 517-524.
-
2021Gut microbiome stability and dynamics in healthy donors and patients with non-gastrointestinal cancers., J Exp Med 2021 Jan; 218(1): .
-
2020Plague as a cause for familial Mediterranean fever., Nat. Immunol. 2020 Jun; (): .
-
2020Two common disease-associated TYK2 variants impact exon splicing and TYK2 dosage., PLoS One 2020 ; 15(1): e0225289.
-
2019A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals., Microbiome 2019 Sep; 7(1): 130.
-
2019Genomic Evidence for Local Adaptation of Hunter-Gatherers to the African Rainforest, Curr. Biol. 2019 Sep;29(17):2926-2935.e4.
-
2018Human thymopoiesis is influenced by a common genetic variant within the TCRA-TCRD locus., Sci Transl Med 2018 Sep; 10(457): .
-
2018Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines., Genome Med 2018 Jul; 10(1): 59.
-
2018IRF4 haploinsufficiency in a family with Whipple’s disease, Elife 2018 Mar;7.
-
2018The demographic history and mutational load of African hunter-gatherers and farmers, Nat Ecol Evol 2018 Apr;2(4):721-730.
-
2018Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors., Nat Immunol 2018 Mar; 19(3): 302-314.
-
2017The Genetic Legacy of the Indian Ocean Slave Trade: Recent Admixture and Post-admixture Selection in the Makranis of Pakistan, Am. J. Hum. Genet. 2017 Dec;101(6):977-984.
-
2017Trends in DNA Methylation with Age Replicate Across Diverse Human Populations, Genetics 2017 07;206(3):1659-1674.
-
2017Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America, Science. 2017 May; 356(6337);543-546.
-
2016Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations, Cell 2016 Oct;167(3):643-656.e17.
-
2016Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations, J. Exp. Med. 2016 10;213(11):2413-2435.
-
2016Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes, Am. J. Hum. Genet. 2016 Jan;98(1):5-21.
-
2015The epigenomic landscape of African rainforest hunter-gatherers and farmers, Nat Commun 2015 Nov;6:10047.
-
2015Extensive Admixture and Selective Pressure Across the Sahel Belt, Genome Biol Evol 2015 Nov;7(12):3484-95.
-
2015The human gene damage index as a gene-level approach to prioritizing exome variants, Proc. Natl. Acad. Sci. U.S.A. 2015 Nov;112(44):13615-20.
-
2015Automated flow cytometric analysis across large numbers of samples and cell types., Clin Immunol 2015 Apr; 157(2): 249-60.
-
2014Impact of common risk factors of fibrosis progression in chronic hepatitis C, Gut 2015 Oct;64(10):1605-15.
-
2014Adaptive, convergent origins of the pygmy phenotype in African rainforest hunter-gatherers, Proc. Natl. Acad. Sci. U.S.A. 2014 09;111(35):E3596-603.
-
2014Exploring the occurrence of classic selective sweeps in humans using whole-genome sequencing data sets, Mol. Biol. Evol. 2014 Jul;31(7):1850-68.
-
2014Heterogeneous pattern of selective pressure for PRRT2 in human populations, but no association with autism spectrum disorders, PLoS ONE 2014;9(3):e88600.
-
2014A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection, Genome Res. 2014 May;24(5):850-9.
-
2014The impact of agricultural emergence on the genetic history of African rainforest hunter-gatherers and agriculturalists, Nat Commun 2014;5:3163.
-
2013A 1,100-year-old founder effect mutation in IL12B gene is responsible for Mendelian susceptibility to mycobacterial disease in Tunisian patients, Immunogenetics 2014 Jan;66(1):67-71.
-
2013Human genetic data reveal contrasting demographic patterns between sedentary and nomadic populations that predate the emergence of farming, Mol. Biol. Evol. 2013 Dec;30(12):2629-44.
-
2013Different selective pressures shape the evolution of Toll-like receptors in human and African great ape populations, Hum. Mol. Genet. 2013 Dec;22(23):4829-40.
-
2013Ribosomal protein SA haploinsufficiency in humans with isolated congenital asplenia, Science 2013 May;340(6135):976-8.
-
2012Positive selection in the chromosome 16 VKORC1 genomic region has contributed to the variability of anticoagulant response in humans, PLoS ONE 2012;7(12):e53049.
-
2012Inherited MST1 deficiency underlies susceptibility to EV-HPV infections, PLoS ONE 2012;7(8):e44010.
-
2012Human RHOH deficiency causes T cell defects and susceptibility to EV-HPV infections, J. Clin. Invest. 2012 Sep;122(9):3239-47.
-
2012Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection, Gastroenterology 2012 Nov;143(5):1244-52.e1-12.
-
2012The evolutionary landscape of cytosolic microbial sensors in humans, Am. J. Hum. Genet. 2012 Jul;91(1):27-37.
-
2011IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes, Hepatology 2012 Feb;55(2):384-94.
-
2011Evolutionary genetic dissection of human interferons, J. Exp. Med. 2011 Dec;208(13):2747-59.
-
2011The selective footprints of viral pressures at the human RIG-I-like receptor family, Hum. Mol. Genet. 2011 Nov;20(22):4462-74.
-
2011Evolutionary genetics evidence of an essential, nonredundant role of the IFN-γ pathway in protective immunity, Hum. Mutat. 2011 Jun;32(6):633-42.
-
2010Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection, Gut 2010 Aug;59(8):1120-6.
-
2010Formulating a historical and demographic model of recent human evolution based on resequencing data from noncoding regions, PLoS ONE 2010;5(4):e10284.
-
2010Parkinson’s disease-related LRRK2 G2019S mutation results from independent mutational events in humans, Hum. Mol. Genet. 2010 May;19(10):1998-2004.
-
2009Positively selected G6PD-Mahidol mutation reduces Plasmodium vivax density in Southeast Asians, Science 2009 Dec;326(5959):1546-9.
-
2009Evolutionary trajectories of primate genes involved in HIV pathogenesis, Mol. Biol. Evol. 2009 Dec;26(12):2865-75.
-
2009Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense, PLoS Genet. 2009 Jul;5(7):e1000562.
-
2009Inferring the demographic history of African farmers and pygmy hunter-gatherers using a multilocus resequencing data set, PLoS Genet. 2009 Apr;5(4):e1000448.
-
2009Signatures of purifying and local positive selection in human miRNAs, Am. J. Hum. Genet. 2009 Mar;84(3):316-27.
-
2008Natural selection has driven population differentiation in modern humans, Nat. Genet. 2008 Mar;40(3):340-5.
-
2008Maternal traces of deep common ancestry and asymmetric gene flow between Pygmy hunter-gatherers and Bantu-speaking farmers, Proc. Natl. Acad. Sci. U.S.A. 2008 Feb;105(5):1596-601.
-
2008Demeter’s legacy: rapid changes to our genome imposed by diet, Trends Ecol. Evol. (Amst.) 2008 Feb;23(2):56-9.
-
2007Population genetic diversity of the NAT2 gene supports a role of acetylation in human adaptation to farming in Central Asia, Eur. J. Hum. Genet. 2008 Feb;16(2):243-51.
-
2006Evolutionary insights into the high worldwide prevalence of MBL2 deficiency alleles, Hum. Mol. Genet. 2006 Sep;15(17):2650-8.
-
2006Sub-Saharan African coding sequence variation and haplotype diversity at the NAT2 gene, Hum. Mutat. 2006 Jul;27(7):720.
-
2006Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes, Am. J. Hum. Genet. 2006 Mar;78(3):423-36.
-
2005The heritage of pathogen pressures and ancient demography in the human innate-immunity CD209/CD209L region, Am. J. Hum. Genet. 2005 Nov;77(5):869-86.