• 2025
  Jean Contreras, Sophie Vichier-Guerre, Laurence Dugué, Frédéric Bonhomme, Corinne Jallet, Minh-Ha Nguyen, Bruno Vitorge, Alessandra Feoli, Gianluca Sbardella, J. I. Guijarro, Paola B Arimondo, In Quest of Chemical Probes for DNA Methylation Reader Proteins: Nucleoside and Dimer Analogues of 5‐Methylcytosine Interact with MBD2, Angewandte Chemie International Edition, In press, pp.e202425599. ⟨10.1002/anie.202425599⟩.
• 2025
  Fruchard L, Babosan A, Carvalho A, Lang M, Li B, Duchateau M, Giai Gianetto Q, Matondo M, Bonhomme F, Hatin I, Arbes H, Fabret C, Corler E, Sanchez G, Marchand V, Motorin Y, Namy O, de Crécy-Lagard V, Mazel D, Baharoglu Z, Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated with queuosine tRNA modification., Elife 2025 Jan; 13(): .
• 2024
  Germain Niogret, Camille Chériaux, Frédéric Bonhomme, Fabienne Levi-Acobas, Carlotta Figliola, Gilles Ulrich, Gilles Gasser* and Marcel Hollenstein*, A toolbox for enzymatic modification of nucleic acids with photosensitizers for photodynamic therapy, RSC Chem. Biol. 2024, 5, 841-852.
• 2024
  Fruchard Louna, Babosan Anamaria, Carvalho Andre, Lang Manon, Li Blaise, Duchateau Magalie, Giai-Gianetto Quentin, Matondo Mariette, Bonhomme Frédéric, Hatin Isabelle, Arbes Hugo, Fabret Céline, Sanchez Guillaume, Marchand Virginie, Motorin Yuri, Namy Olivier, de Crécy-Lagard Valérie, Mazel Didier, Baharoglu Zeynep, Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated to queuosine tRNA modification, Elife.
• 2024
  Mistretta M, Cimino M, Campagne P, Volant S, Kornobis E, Hebert O, Rochais C, Dallemagne P, Lecoutey C, Tisnerat C, Lepailleur A, Ayotte Y, LaPlante SR, Gangneux N, Záhorszká M, Korduláková J, Vichier-Guerre S, Bonhomme F, Pokorny L, Albert M, Tinevez JY, Manina G, Dynamic microfluidic single-cell screening identifies pheno-tuning compounds to potentiate tuberculosis therapy., Nat Commun 2024 May; 15(1): 4175.
• 2024
  , Dynamic microfluidic single-cell screening identifies pheno-tuning compounds to potentiate tuberculosis therapy, Nature Communications.
• 2024
  Yamaguchi K, Chen X, Rodgers B, Miura F, Bashtrykov P, Bonhomme F, Salinas-Luypaert C, Haxholli D, Gutekunst N, Aygenli BÖ, Ferry L, Kirsh O, Laisné M, Scelfo A, Ugur E, Arimondo PB, Leonhardt H, Kanemaki MT, Bartke T, Fachinetti D, Jeltsch A, Ito T, Defossez , Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells, Nature communication.
• 2024
  Yamaguchi K, Chen X, Rodgers B, Miura F, Bashtrykov P, Bonhomme F, Salinas-Luypaert C, Haxholli D, Gutekunst N, Aygenli BÖ, Ferry L, Kirsh O, Laisné M, Scelfo A, Ugur E, Arimondo PB, Leonhardt H, Kanemaki MT, Bartke T, Fachinetti D, Jeltsch A, Ito T, Defossez PA. , Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells, Nature Communications.
• 2024
  Scelfo A, Barra V, Abdennur N, Spracklin G, Busato F, Salinas-Luypaert C, Bonaiti E, Velasco G, Bonhomme F, Chipont A, Tijhuis AE, Spierings DCJ, Guérin C, Arimondo P, Francastel C, Foijer F, Tost J, Mirny L, Fachinetti D, Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization., J Cell Biol 2024 Apr; 223(4): .
• 2024
  Germain Niogret, Pascal Röthlisberger, Fabienne Levi-Acobas, Frédéric Bonhomme, Gilles Gasser, Marcel Hollenstein∗, Facilitated Synthetic Access to Boronic Acid-Modified Nucleoside Triphosphates and Compatibility with Enzymatic DNA Synthesis, Synlett 2024, 35, 677-683.
• 2024
  Andrea Scelfo, Viviana Barra, Nezar Abdennur, George Spracklin, Florence Busato, Catalina Salinas Luypaert, Elena Bonaiti, Guillaume Velasco, Frédéric Bonhomme, Anna Chipont, Andréa Tijhuis, Diana Spierings, Coralie Guerin, Paola B Arimondo, Claire Francastel, Floris Foijer, Jörg Tost, Leonid Mirny, and Daniele Fachinetti. , Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization, J Cell Biol.
• 2024
  Germain Niogret, Alix Bouvier-Müller, Chiara Figazzolo, Jack M. Joyce, Frédéric Bonhomme, Patrick England, Olena Mayboroda, Riccardo Pellarin, Gilles Gasser, James H. R. Tucker, Julian A. Tanner, G. Paul Savage, Marcel Hollenstein*, Interrogating Aptamer Chemical Space Through Modified Nucleotide Substitution Facilitated by Enzymatic DNA Synthesis, ChemBioChem 2024, 25, e202300539.
• 2023
  Canat A, Veillet A, Batrin R, Dubourg C, Lhoumaud P, Arnau-Romero P, Greenberg MVC, Bonhomme F, Arimondo PB, Illingworth R, Fabre E, Therizols P. , DAXX safeguards heterochromatin formation in embryonic stem cells, Journal Of Cell Science.
• 2023
  Antoine Canat, Adeline Veillet, Renaud Batrin, Clara Dubourg, Priscillia Lhoumaud, Pol Arnau-Romero, Maxim V C Greenberg, Frédéric Bonhomme, Paola B Arimondo, Robert Illingworth, Emmanuelle Fabre, Pierre Therizols, DAXX safeguards heterochromatin formation in embryonic stem cells, J Cell Sci. 2023 Sep 1:jcs.261092. doi: 10.1242/jcs.261092. Epub ahead of print. PMID: 37655670..
• 2023
  Yakhou L, Azogui A, Gupta N, Albert JR, Miura F, Ferry L, Yamaguchi K, Battault S, Therizols P, Bonhomme F, Bethuel E, Sarkar A, Greenberg MVC, Arimondo PB, Cristofari G, Kirsh O, Ito T, Defossez PA, A genetic screen identifies BEND3 as a regulator of bivalent gene expression and global DNA methylation, Nucleic Acids Res. 2023 Aug 31.
• 2023
  Yakhou L, Azogui A, Gupta N, Albert JR, Miura F, Ferry L, Yamaguchi K, Battault S, Therizols P, Bonhomme F, Bethuel E, Sarkar A, Greenberg MVC, Arimondo PB, Cristofari G, Kirsh O, Ito T, Defossez PA, A genetic screen identifies BEND3 as a regulator of bivalent gene expression and global DNA methylation, Nucleic Acids Research.
• 2023
  Gupta N, Yakhou L, Albert JR, Azogui A, Ferry L, Kirsh O, Miura F, Battault S, Yamaguchi K, Laisné M, Domrane C, Bonhomme F, Sarkar A, Delagrange M, Ducos B, Cristofari G, Ito T, Greenberg MVC, Defossez PA, A genome-wide screen reveals new regulators of the 2-cell-like cell state, Nat Struct Mol Biol 30, 1105–1118 (2023).
• 2023
  Gupta N, Yakhou L, Albert JR, Azogui A, Ferry L, Kirsh O, Miura F, Battault S, Yamaguchi K, Laisné M, Domrane C, Bonhomme F, Sarkar A, Delagrange M, Ducos B, Cristofari G, Ito T, Greenberg MVC, Defossez PA., A genome-wide screenreveals new regulators of the 2-cell-like cell state, Nat Struct Mol Biol.
• 2022
  Chiara Figazzolo, Frédéric Bonhomme, Saidbakhrom Saidjalolov, Mélanie Ethève-Quelquejeu, and Marcel Hollenstein*, Enzymatic Synthesis of Vancomycin-Modified DNA, Molecules 2022, 27, 8927.
• 2022
  Luke K. McKenzie‡, Marie Flamme‡, Patrick S. Felder, Johannes Karges, Frederic Bonhomme, Albert Gandioso, Christian Malosse, Gilles Gasser* and Marcel Hollenstein*, A ruthenium-oligonucleotide bioconjugated photosensitizing aptamer for cancer cell specific photodynamic therapy, RSC Chem. Biol., 2022, 3, 85-95.
• 2021
  Elie Hammam, Ameya Sinha, Sebastian Baumgarten, Flore Nardella, Jiaqi Liang, Samia Miled, Frédéric Bonhomme, Diane Erdmann, Benoit Arcangioli, Paola B. Arimondo, Peter Dedon, Peter Preiser, Artur Scherf, Malaria Parasite Stress Tolerance Is Regulated by DNMT2-Mediated tRNA Cytosine Methylation, mBio. 2021 Nov-Dec; 12(6): e02558-21.
• 2021
  Luke K. McKenzie, Marie Flamme, Patrick S. Felder, Johannes Karges, Frederic Bonhomme, Albert Gandioso, Christian Malosse, Gilles Gasser, Marcel Hollenstein, A ruthenium-oligonucleotide bioconjugated photosensitizing aptamer for cancer cell specific photodynamic therapy, RSC Chemical Biology.
• 2021
  Czernecki D, Bonhomme F, Kaminski PA, Delarue M , Characterization of a triad of genes in cyanophage S-2L sufficient to replace adenine by 2-aminoadenine in bacterial DNA., Nat Commun 2021 08; 12(1): 4710.
• 2021
  Czernecki D., Bonhomme F., Kaminski PA. and Delarue M., Characterization of a triad of genes in cyanophage S-2Lsufficient to replace adenine by 2-aminoadenine in bacterial DNA, NATURE.
• 2021
  Nikhil Gupta, Lounis Yakhou, Julien Richard Albert, Fumihito Miura, Laure Ferry, Olivier Kirsh, Marthe Laisné, Kosuke Yamaguchi, Cécilia Domrane, Frédéric Bonhomme, Arpita Sarkar, Marine Delagrange, Bertrand Ducos, Maxim V. C. Greenberg, Gael Cristofari, Sebastian Bultmann, Takashi Ito, Pierre-Antoine Defossez, A genome-wide knock-out screen for actors of epigenetic silencing reveals new regulators of germline genes and 2-cell like cell state, bioRxiv 2021.05.03.442415.
• 2017
  S. Vichier-Guerre, L. Dugué, F. Bonhomme and S. Pochet, An expedient synthesis of flexible nucleosides via a regiocontrolled enzymatic glycosylation of functionalized imidazoles, Org. Biomol. Chem., 2017, 15, 8193.
• 2017
  Bannantine JP, Etienne G, Laval F, Stabel JR, Lemassu A, Daffé M, Bayles DO, Ganneau C, Bonhomme F, Branger M, Cochard T, Bay S, Biet F, , Cell wall peptidolipids of Mycobacterium avium: from genetic prediction to exact structure of a nonribosomal peptide., Mol Microbiol 2017 Aug; 105(4): 525-539.
• 2017
  Christelle Ganneau, Catherine Simenel, Emeline Emptas, Tiphanie Courtiol, Yves-Marie Coïc, Cécile Artaud, Edith Dériaud, Frédéric Bonhomme, Muriel Delepierre, Claude Leclerc, Richard Lo-Man and Sylvie Bay, Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate, Organic & Biomolecular Chemistry, 2017, 15, 114 - 123.
• 2016
  Ganneau C, Simenel C, Emptas E, Courtiol T, Coïc YM, Artaud C, Dériaud E, Bonhomme F, Delepierre M, Leclerc C, Lo-Man R, Bay S, Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate, Org. Biomol. Chem. 2016 Dec;15(1):114-123.
• 2016
  S. Vichier-Guerre, L. Dugué, F. Bonhomme and S. Pochet, Expedient and generic synthesis of imidazole nucleosides by enzymatic transglycosylation, Org. Biomol. Chem., 2016, 14, 3638.
• 2016
  Stéphanie Petrella, Alexandra Aubry, Geneviève Janvier, Eloi Paul Coutant, Alex Cartier, Thuy-Ha Dao, Frédéric Bonhomme, Laurence Motreff, Cédric Pissis, Chantal Bizet, Dominique Clermont, Evelyne Begaud, Pascal Retailleau, Hélène Munier-Lehmann, Estelle Capton, Claudine Mayer, Yves Janin, Synthesis and evaluation of original bioisosteres of bacterial type IIA topoisomerases inhibitors, Can. J. Chem. 2016, 94 , 240-250.
• 2012
  Salanouve, E.; Guillou, S.; Bizouarne, M.; Bonhomme, F. J.; Janin, Y. L., 3-Methoxypyrazoles from 1,1-dimethoxyethene, few original results, Tetrahedron 2012, 68, 3165-3171.
• 2011
  Guillou, S.; Bonhomme, F. J.; Ermolenko, M. S.; Janin, Y. L., Simple preparations of 4 and 5-iodinated pyrazoles as useful building blocks, Tetrahedron 2011, 67, 8451-8457.
• 2010
  Guillou, S.; Bonhomme, F. J.; Chahine, D.; Nesme, O.; Janin, Y. L., N-arylation of 3-alkoxypyrazoles, the case of the pyridines, Tetrahedron 2010, 66, 2654-2663.
• 2009
  Bay S, Fort S, Birikaki L, Ganneau C, Samain E, Coïc YM, Bonhomme F, Dériaud E, Leclerc C, Lo-Man R, Induction of a melanoma-specific antibody response by a monovalent, but not a divalent, synthetic GM2 neoglycopeptide, ChemMedChem 2009 Apr;4(4):582-7.
• 2009
  Guillou, S.; Bonhomme, F. J.; Janin, Y. L., Nitrogen’s reactivity of various 3-alkoxypyrazoles, Tetrahedron 2009, 65, 2660-2668.
• 2008
  Guillou, S.; Bonhomme, F. J.; Janin, Y. L., An improved preparation of 3-alkoxypyrazoles, Synthesis 2008, 3504-3508.