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  • 2023
    Cioetto-Mazzabò L, Boldrin F, Beauvineau C, Speth M, Marina A, Namouchi A, Segafreddo G, Cimino M, Favre-Rochex S, Balasingham S, Trastoy B, Munier-Lehmann H, Griffiths G, Gicquel B, Guerin ME, Manganelli R, Alonso-Rodríguez N, , SigH stress response mediates killing of Mycobacterium tuberculosis by activating nitronaphthofuran prodrugs via induction of Mrx2 expression., Nucleic Acids Res 2023 Jan; 51(1): 144-165.
  • 2020
    Giraud-Gatineau A, Coya JM, Maure A, Biton A, Thomson M, Bernard EM, Marrec J, Gutierrez MG, Larrouy-Maumus G, Brosch R, Gicquel B, Tailleux L, The antibiotic bedaquiline activates host macrophage innate immune resistance to bacterial infection, Elife 2020 May;9.
  • 2017
    Buchieri MV, Cimino M, Rebollo-Ramirez S, Beauvineau C, Cascioferro A, Favre-Rochex S, Helynck O, Naud-Martin D, Larrouy-Maumus G, Munier-Lehmann H, Gicquel B, Nitazoxanide Analogs Require Nitroreduction for Antimicrobial Activity in Mycobacterium smegmatis, J. Med. Chem. 2017 Sep 14;60(17):7425-7433.
  • 2015
    Siddle KJ, Tailleux L, Deschamps M, Loh YH, Deluen C, Gicquel B, Antoniewski C, Barreiro LB, Farinelli L, Quintana-Murci L, bacterial infection drives the expression dynamics of microRNAs and their isomiRs, PLoS Genet. 2015 Mar;11(3):e1005064.
  • 2014
    Solans L, Uranga S, Aguilo N, Arnal C, Gomez AB, Monzon M, Badiola JJ, Gicquel B, Martin C, Hyper-attenuated MTBVAC erp mutant protects against tuberculosis in mice, Vaccine 2014 Sep;32(40):5192-7.
  • 2014
    Dubois-Colas N, Petit-Jentreau L, Barreiro LB, Durand S, Soubigou G, Lecointe C, Klibi J, Rezaï K, Lokiec F, Coppée JY, Gicquel B, Tailleux L, Extracellular adenosine triphosphate affects the response of human macrophages infected with Mycobacterium tuberculosis, J. Infect. Dis. 2014 Sep;210(5):824-33.
  • 2014
    Siddle KJ, Deschamps M, Tailleux L, Nédélec Y, Pothlichet J, Lugo-Villarino G, Libri V, Gicquel B, Neyrolles O, Laval G, Patin E, Barreiro LB, Quintana-Murci L, A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection, Genome Res. 2014 May;24(5):850-9.
  • 2013
    Arbues A, Aguilo JI, Gonzalo-Asensio J, Marinova D, Uranga S, Puentes E, Fernandez C, Parra A, Cardona PJ, Vilaplana C, Ausina V, Williams A, Clark S, Malaga W, Guilhot C, Gicquel B, Martin C, Construction, characterization and preclinical evaluation of MTBVAC, the first live-attenuated M. tuberculosis-based vaccine to enter clinical trials, Vaccine 2013 Oct;31(42):4867-73.
  • 2013
    Rakotosamimanana N, Doherty TM, Andriamihantasoa LH, Richard V, Gicquel B, Soares JL, Zumla A, Razanamparany VR, Expression of TNF-alpha-dependent apoptosis-related genes in the peripheral blood of Malagasy subjects with tuberculosis, PLoS ONE 2013;8(4):e61154.
  • 2013
    Wang CC, Zhu B, Fan X, Gicquel B, Zhang Y, Systems approach to tuberculosis vaccine development, Respirology 2013 Apr;18(3):412-20.
  • 2013
    Mestre O, Hurtado-Ortiz R, Dos Vultos T, Namouchi A, Cimino M, Pimentel M, Neyrolles O, Gicquel B, High throughput phenotypic selection of Mycobacterium tuberculosis mutants with impaired resistance to reactive oxygen species identifies genes important for intracellular growth, PLoS ONE 2013;8(1):e53486.
  • 2012
    Fanny ML, Beyam N, Gody JC, Zandanga G, Yango F, Manirakiza A, Rigouts L, Pierre-Audigier C, Gicquel B, Bobossi G, Fine-needle aspiration for diagnosis of tuberculous lymphadenitis in children in Bangui, Central African Republic, BMC Pediatr 2012;12:191.
  • 2012
    Butler RE, Brodin P, Jang J, Jang MS, Robertson BD, Gicquel B, Stewart GR, The balance of apoptotic and necrotic cell death in Mycobacterium tuberculosis infected macrophages is not dependent on bacterial virulence, PLoS ONE 2012;7(10):e47573.
  • 2012
    Grzegorzewicz AE, Korduláková J, Jones V, Born SE, Belardinelli JM, Vaquié A, Gundi VA, Madacki J, Slama N, Laval F, Vaubourgeix J, Crew RM, Gicquel B, Daffé M, Morbidoni HR, Brennan PJ, Quémard A, McNeil MR, Jackson M, A common mechanism of inhibition of the Mycobacterium tuberculosis mycolic acid biosynthetic pathway by isoxyl and thiacetazone, J. Biol. Chem. 2012 Nov;287(46):38434-41.
  • 2012
    Cimino M, Thomas C, Namouchi A, Dubrac S, Gicquel B, Gopaul DN, Identification of DNA binding motifs of the Mycobacterium tuberculosis PhoP/PhoR two-component signal transduction system, PLoS ONE 2012;7(8):e42876.
  • 2012
    Zhang Y, Chiu Chang K, Leung CC, Wai Yew W, Gicquel B, Fallows D, Kaplan G, Chaisson RE, Zhang W, ‘Z(S)-MDR-TB’ versus ‘Z(R)-MDR-TB’: improving treatment of MDR-TB by identifying pyrazinamide susceptibility, Emerg Microbes Infect 2012 Jul;1(7):e5.
  • 2012
    Wu K, Dong D, Fang H, Levillain F, Jin W, Mei J, Gicquel B, Du Y, Wang K, Gao Q, Neyrolles O, Zhang J, An interferon-related signature in the transcriptional core response of human macrophages to Mycobacterium tuberculosis infection, PLoS ONE 2012;7(6):e38367.
  • 2012
    Namouchi A, Didelot X, Schöck U, Gicquel B, Rocha EP, After the bottleneck: Genome-wide diversification of the Mycobacterium tuberculosis complex by mutation, recombination, and natural selection, Genome Res. 2012 Apr;22(4):721-34.
  • 2012
    Nessar R, Cambau E, Reyrat JM, Murray A, Gicquel B, Mycobacterium abscessus: a new antibiotic nightmare, J. Antimicrob. Chemother. 2012 Apr;67(4):810-8.
  • 2012
    Luo T, Yang C, Gagneux S, Gicquel B, Mei J, Gao Q, Combination of single nucleotide polymorphism and variable-number tandem repeats for genotyping a homogenous population of Mycobacterium tuberculosis Beijing strains in China, J. Clin. Microbiol. 2012 Mar;50(3):633-9.
  • 2012
    Barreiro LB, Tailleux L, Pai AA, Gicquel B, Marioni JC, Gilad Y, Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection, Proc. Natl. Acad. Sci. U.S.A. 2012 Jan;109(4):1204-9.
  • 2012
    Bierne H, Travier L, Mahlakõiv T, Tailleux L, Subtil A, Lebreton A, Paliwal A, Gicquel B, Staeheli P, Lecuit M, Cossart P, , Activation of type III interferon genes by pathogenic bacteria in infected epithelial cells and mouse placenta., PLoS One 2012 ; 7(6): e39080.
  • 2011
    Boniotto M, Tailleux L, Lomma M, Gicquel B, Buchrieser C, Garcia S, Quintana-Murci L, Population variation in NAIP functional copy number confers increased cell death upon Legionella pneumophila infection, Hum. Immunol. 2012 Feb;73(2):196-200.
  • 2011
    Surcouf C, Heng S, Pierre-Audigier C, Cadet-Daniel V, Namouchi A, Murray A, Gicquel B, Guillard B, Molecular detection of fluoroquinolone-resistance in multi-drug resistant tuberculosis in Cambodia suggests low association with XDR phenotypes, BMC Infect. Dis. 2011;11:255.
  • 2011
    Botella H, Peyron P, Levillain F, Poincloux R, Poquet Y, Brandli I, Wang C, Tailleux L, Tilleul S, Charrière GM, Waddell SJ, Foti M, Lugo-Villarino G, Gao Q, Maridonneau-Parini I, Butcher PD, Castagnoli PR, Gicquel B, de Chastellier C, Neyrolles O, Mycobacterial p(1)-type ATPases mediate resistance to zinc poisoning in human macrophages, Cell Host Microbe 2011 Sep;10(3):248-59.
  • 2011
    Nessar R, Reyrat JM, Murray A, Gicquel B, Genetic analysis of new 16S rRNA mutations conferring aminoglycoside resistance in Mycobacterium abscessus, J. Antimicrob. Chemother. 2011 Aug;66(8):1719-24.
  • 2011
    Miranda SS, Carvalho Wda S, Suffys PN, Kritski AL, Oliveira M, Zarate N, Zozio T, Rastogi N, Gicquel B, Spoligotyping of clinical Mycobacterium tuberculosis isolates from the state of Minas Gerais, Brazil, Mem. Inst. Oswaldo Cruz 2011 May;106(3):267-73.
  • 2011
    Martín Montañés C, Gicquel B, New tuberculosis vaccines, Enferm. Infecc. Microbiol. Clin. 2011 Mar;29 Suppl 1:57-62.
  • 2011
    Zhang J, Heng S, Le Moullec S, Refregier G, Gicquel B, Sola C, Guillard B, A first assessment of the genetic diversity of Mycobacterium tuberculosis complex in Cambodia, BMC Infect. Dis. 2011;11:42.
  • 2011
    Mestre O, Luo T, Dos Vultos T, Kremer K, Murray A, Namouchi A, Jackson C, Rauzier J, Bifani P, Warren R, Rasolofo V, Mei J, Gao Q, Gicquel B, Phylogeny of Mycobacterium tuberculosis Beijing strains constructed from polymorphisms in genes involved in DNA replication, recombination and repair, PLoS ONE 2011;6(1):e16020.
  • 2011
    Alonso H, Aguilo JI, Samper S, Caminero JA, Campos-Herrero MI, Gicquel B, Brosch R, Martín C, Otal I, Deciphering the role of IS6110 in a highly transmissible Mycobacterium tuberculosis Beijing strain, GC1237, Tuberculosis (Edinb) 2011 Mar;91(2):117-26.
  • 2010
    Skovierová H, Larrouy-Maumus G, Pham H, Belanová M, Barilone N, Dasgupta A, Mikusová K, Gicquel B, Gilleron M, Brennan PJ, Puzo G, Nigou J, Jackson M, Biosynthetic origin of the galactosamine substituent of Arabinogalactan in Mycobacterium tuberculosis, J. Biol. Chem. 2010 Dec;285(53):41348-55.
  • 2010
    Wang C, Peyron P, Mestre O, Kaplan G, van Soolingen D, Gao Q, Gicquel B, Neyrolles O, Innate immune response to Mycobacterium tuberculosis Beijing and other genotypes, PLoS ONE 2010;5(10):e13594.
  • 2010
    Ferrer NL, Gomez AB, Neyrolles O, Gicquel B, Martin C, Interactions of attenuated Mycobacterium tuberculosis phoP mutant with human macrophages, PLoS ONE 2010;5(9):e12978.
  • 2010
    Brodin P, Poquet Y, Levillain F, Peguillet I, Larrouy-Maumus G, Gilleron M, Ewann F, Christophe T, Fenistein D, Jang J, Jang MS, Park SJ, Rauzier J, Carralot JP, Shrimpton R, Genovesio A, Gonzalo-Asensio JA, Puzo G, Martin C, Brosch R, Stewart GR, Gicquel B, Neyrolles O, High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling, PLoS Pathog. 2010;6(9):e1001100.
  • 2010
    Dasgupta A, Sureka K, Mitra D, Saha B, Sanyal S, Das AK, Chakrabarti P, Jackson M, Gicquel B, Kundu M, Basu J, An oligopeptide transporter of Mycobacterium tuberculosis regulates cytokine release and apoptosis of infected macrophages, PLoS ONE 2010;5(8):e12225.
  • 2010
    Abadia E, Zhang J, dos Vultos T, Ritacco V, Kremer K, Aktas E, Matsumoto T, Refregier G, van Soolingen D, Gicquel B, Sola C, Resolving lineage assignation on Mycobacterium tuberculosis clinical isolates classified by spoligotyping with a new high-throughput 3R SNPs based method, Infect. Genet. Evol. 2010 Oct;10(7):1066-74.
  • 2010
    Rakotosamimanana N, Raharimanga V, Andriamandimby SF, Soares JL, Doherty TM, Ratsitorahina M, Ramarokoto H, Zumla A, Huggett J, Rook G, Richard V, Gicquel B, Rasolofo-Razanamparany V, , Variation in gamma interferon responses to different infecting strains of Mycobacterium tuberculosis in acid-fast bacillus smear-positive patients and household contacts in Antananarivo, Madagascar, Clin. Vaccine Immunol. 2010 Jul;17(7):1094-103.
  • 2010
    Jang J, Stella A, Boudou F, Levillain F, Darthuy E, Vaubourgeix J, Wang C, Bardou F, Puzo G, Gilleron M, Burlet-Schiltz O, Monsarrat B, Brodin P, Gicquel B, Neyrolles O, Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ, Microbiology (Reading, Engl.) 2010 Jun;156(Pt 6):1619-31.
  • 2009
    Skovierová H, Larrouy-Maumus G, Zhang J, Kaur D, Barilone N, Korduláková J, Gilleron M, Guadagnini S, Belanová M, Prevost MC, Gicquel B, Puzo G, Chatterjee D, Brennan PJ, Nigou J, Jackson M, AftD, a novel essential arabinofuranosyltransferase from mycobacteria, Glycobiology 2009 Nov;19(11):1235-47.
  • 2009
    Barreiro LB, Ben-Ali M, Quach H, Laval G, Patin E, Pickrell JK, Bouchier C, Tichit M, Neyrolles O, Gicquel B, Kidd JR, Kidd KK, Alcaïs A, Ragimbeau J, Pellegrini S, Abel L, Casanova JL, Quintana-Murci L, Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense, PLoS Genet. 2009 Jul;5(7):e1000562.
  • 2009
    Dos Vultos T, Mestre O, Tonjum T, Gicquel B, DNA repair in Mycobacterium tuberculosis revisited, FEMS Microbiol. Rev. 2009 May;33(3):471-87.
  • 2009
    Verreck FA, Vervenne RA, Kondova I, van Kralingen KW, Remarque EJ, Braskamp G, van der Werff NM, Kersbergen A, Ottenhoff TH, Heidt PJ, Gilbert SC, Gicquel B, Hill AV, Martin C, McShane H, Thomas AW, MVA.85A boosting of BCG and an attenuated, phoP deficient M. tuberculosis vaccine both show protective efficacy against tuberculosis in rhesus macaques, PLoS ONE 2009;4(4):e5264.
  • 2008
    Ferrer NL, Gómez AB, Soto CY, Neyrolles O, Gicquel B, García-Del Portillo F, Martín C, Intracellular replication of attenuated Mycobacterium tuberculosis phoP mutant in the absence of host cell cytotoxicity, Microbes Infect. 2009 Jan;11(1):115-22.
  • 2008
    Gonzalo-Asensio J, Mostowy S, Harders-Westerveen J, Huygen K, Hernández-Pando R, Thole J, Behr M, Gicquel B, Martín C, PhoP: a missing piece in the intricate puzzle of Mycobacterium tuberculosis virulence, PLoS ONE 2008;3(10):e3496.
  • 2008
    Sambou T, Dinadayala P, Stadthagen G, Barilone N, Bordat Y, Constant P, Levillain F, Neyrolles O, Gicquel B, Lemassu A, Daffé M, Jackson M, Capsular glucan and intracellular glycogen of Mycobacterium tuberculosis: biosynthesis and impact on the persistence in mice, Mol. Microbiol. 2008 Nov;70(3):762-74.
  • 2008
    Gicquel B, Tuberculosis: in it for the long haul, Bull. World Health Organ. 2008 Sep;86(9):667-8.
  • 2008
    Gonzalo-Asensio J, Soto CY, Arbués A, Sancho J, del Carmen Menéndez M, García MJ, Gicquel B, Martín C, The Mycobacterium tuberculosis phoPR operon is positively autoregulated in the virulent strain H37Rv, J. Bacteriol. 2008 Nov;190(21):7068-78.
  • 2008
    Jordao L, Lengeling A, Bordat Y, Boudou F, Gicquel B, Neyrolles O, Becker PD, Guzman CA, Griffiths G, Anes E, Effects of omega-3 and -6 fatty acids on Mycobacterium tuberculosis in macrophages and in mice, Microbes Infect. 2008 Oct;10(12-13):1379-86.
  • 2008
    Jang J, Becq J, Gicquel B, Deschavanne P, Neyrolles O, Horizontally acquired genomic islands in the tubercle bacilli, Trends Microbiol. 2008 Jul;16(7):303-8.
  • 2008
    Bifani P, Mathema B, Kurepina N, Shashkina E, Bertout J, Blanchis AS, Moghazeh S, Driscoll J, Gicquel B, Frothingham R, Kreiswirth BN, The evolution of drug resistance in Mycobacterium tuberculosis: from a mono-rifampin-resistant cluster into increasingly multidrug-resistant variants in an HIV-seropositive population, J. Infect. Dis. 2008 Jul;198(1):90-4.
  • 2008
    Dos Vultos T, Mestre O, Rauzier J, Golec M, Rastogi N, Rasolofo V, Tonjum T, Sola C, Matic I, Gicquel B, Evolution and diversity of clonal bacteria: the paradigm of Mycobacterium tuberculosis, PLoS ONE 2008;3(2):e1538.
  • 2008
    Frigui W, Bottai D, Majlessi L, Monot M, Josselin E, Brodin P, Garnier T, Gicquel B, Martin C, Leclerc C, Cole ST, Brosch R, Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP, PLoS Pathog. 2008 Feb;4(2):e33.
  • 2008
    Morel C, Badell E, Abadie V, Robledo M, Setterblad N, Gluckman JC, Gicquel B, Boudaly S, Winter N, Mycobacterium bovis BCG-infected neutrophils and dendritic cells cooperate to induce specific T cell responses in humans and mice, Eur. J. Immunol. 2008 Feb;38(2):437-47.
  • 2008
    Asensio JA, Arbués A, Pérez E, Gicquel B, Martin C, Live tuberculosis vaccines based on phoP mutants: a step towards clinical trials, Expert Opin Biol Ther 2008 Feb;8(2):201-11.
  • 2008
    Gibson AL, Huard RC, Gey van Pittius NC, Lazzarini LC, Driscoll J, Kurepina N, Zozio T, Sola C, Spindola SM, Kritski AL, Fitzgerald D, Kremer K, Mardassi H, Chitale P, Brinkworth J, Garcia de Viedma D, Gicquel B, Pape JW, van Soolingen D, Kreiswirth BN, Warren RM, van Helden PD, Rastogi N, Suffys PN, Lapa e Silva J, Ho JL, Application of sensitive and specific molecular methods to uncover global dissemination of the major RDRio Sublineage of the Latin American-Mediterranean Mycobacterium tuberculosis spoligotype family, J. Clin. Microbiol. 2008 Apr;46(4):1259-67.
  • 2008
    Tailleux L, Waddell SJ, Pelizzola M, Mortellaro A, Withers M, Tanne A, Castagnoli PR, Gicquel B, Stoker NG, Butcher PD, Foti M, Neyrolles O, Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages, PLoS ONE 2008;3(1):e1403.
  • 2008
    Fonvielle M, Coinçon M, Daher R, Desbenoit N, Kosieradzka K, Barilone N, Gicquel B, Sygusch J, Jackson M, Therisod M, Synthesis and biochemical evaluation of selective inhibitors of class II fructose bisphosphate aldolases: towards new synthetic antibiotics, Chemistry 2008;14(28):8521-9.
  • 2007
    Ben-Ali M, Barreiro LB, Chabbou A, Haltiti R, Braham E, Neyrolles O, Dellagi K, Gicquel B, Quintana-Murci L, Barbouche MR, Promoter and neck region length variation of DC-SIGN is not associated with susceptibility to tuberculosis in Tunisian patients, Hum. Immunol. 2007 Nov;68(11):908-12.
  • 2007
    Martinez V, Carcelain G, Badell E, Jouan M, Mauger I, Sellier P, Truffot C, Bricaire F, Arend SM, Ottenhoff T, Autran B, Gicquel B, T-cell and serological responses to Erp, an exported Mycobacterium tuberculosis protein, in tuberculosis patients and healthy individuals, BMC Infect. Dis. 2007 Jul;7:83.
  • 2007
    Stadthagen G, Sambou T, Guerin M, Barilone N, Boudou F, Korduláková J, Charles P, Alzari PM, Lemassu A, Daffé M, Puzo G, Gicquel B, Rivière M, Jackson M, Genetic basis for the biosynthesis of methylglucose lipopolysaccharides in Mycobacterium tuberculosis, J. Biol. Chem. 2007 Sep;282(37):27270-6.
  • 2007
    Becq J, Gutierrez MC, Rosas-Magallanes V, Rauzier J, Gicquel B, Neyrolles O, Deschavanne P, Contribution of horizontally acquired genomic islands to the evolution of the tubercle bacilli, Mol. Biol. Evol. 2007 Aug;24(8):1861-71.
  • 2007
    Guerin ME, Kordulakova J, Schaeffer F, Svetlikova Z, Buschiazzo A, Giganti D, Gicquel B, Mikusova K, Jackson M, Alzari PM, Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria, J. Biol. Chem. 2007 Jul;282(28):20705-14.
  • 2007
    Nouvel LX, Dos Vultos T, Kassa-Kelembho E, Rauzier J, Gicquel B, A non-sense mutation in the putative anti-mutator gene ada/alkA of Mycobacterium tuberculosis and M. bovis isolates suggests convergent evolution, BMC Microbiol. 2007;7:39.
  • 2007
    Kordulakova, J.; Janin, Y. L.; Liav, A.; Barilone, N.; Vultos, T. D.; Rauzier, J.; Brennan, P. J.; Gicquel, B.; Jackson, M., Isoxyl activation is required for bacteriostatic activity against Mycobacterium tuberculosis, Antimicrob. Agents Chemother. 2007, 51, 3824-3829.
  • 2006
    Neyrolles O, Hernández-Pando R, Pietri-Rouxel F, Fornès P, Tailleux L, Barrios Payán JA, Pivert E, Bordat Y, Aguilar D, Prévost MC, Petit C, Gicquel B, Is adipose tissue a place for Mycobacterium tuberculosis persistence?, PLoS ONE 2006;1:e43.
  • 2006
    Vultos TD, Méderlé I, Abadie V, Pimentel M, Moniz-Pereira J, Gicquel B, Reyrat JM, Winter N, Modification of the mycobacteriophage Ms6 attP core allows the integration of multiple vectors into different tRNAala T-loops in slow- and fast-growing mycobacteria, BMC Mol. Biol. 2006;7:47.
  • 2006
    Barreiro LB, Neyrolles O, Babb CL, van Helden PD, Gicquel B, Hoal EG, Quintana-Murci L, Length variation of DC-SIGN and L-SIGN neck-region has no impact on tuberculosis susceptibility, Hum. Immunol. 2007 Feb;68(2):106-12.
  • 2006
    Rigden RC, Jandhyala DM, Dupont C, Crosbie-Caird D, Lopez-Villalobos N, Maeda N, Gicquel B, Murray A, Humoral and cellular immune responses in sheep immunized with a 22 kilodalton exported protein of Mycobacterium avium subspecies paratuberculosis, J. Med. Microbiol. 2006 Dec;55(Pt 12):1735-40.
  • 2006
    Rosas-Magallanes V, Stadthagen-Gomez G, Rauzier J, Barreiro LB, Tailleux L, Boudou F, Griffin R, Nigou J, Jackson M, Gicquel B, Neyrolles O, Signature-tagged transposon mutagenesis identifies novel Mycobacterium tuberculosis genes involved in the parasitism of human macrophages, Infect. Immun. 2007 Jan;75(1):504-7.
  • 2006
    Jackson M, Stadthagen G, Gicquel B, Long-chain multiple methyl-branched fatty acid-containing lipids of Mycobacterium tuberculosis: biosynthesis, transport, regulation and biological activities, Tuberculosis (Edinb) 2007 Mar;87(2):78-86.
  • 2006
    Fernandez P, Saint-Joanis B, Barilone N, Jackson M, Gicquel B, Cole ST, Alzari PM, The Ser/Thr protein kinase PknB is essential for sustaining mycobacterial growth, J. Bacteriol. 2006 Nov;188(22):7778-84.
  • 2006
    Nouvel LX, Kassa-Kelembho E, Dos Vultos T, Zandanga G, Rauzier J, Lafoz C, Martin C, Blazquez J, Talarmin A, Gicquel B, Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic, Emerging Infect. Dis. 2006 Sep;12(9):1454-6.
  • 2006
    Kaur D, Berg S, Dinadayala P, Gicquel B, Chatterjee D, McNeil MR, Vissa VD, Crick DC, Jackson M, Brennan PJ, Biosynthesis of mycobacterial lipoarabinomannan: role of a branching mannosyltransferase, Proc. Natl. Acad. Sci. U.S.A. 2006 Sep;103(37):13664-9.
  • 2006
    Neyrolles O, Gicquel B, Quintana-Murci L, Towards a crucial role for DC-SIGN in tuberculosis and beyond, Trends Microbiol. 2006 Sep;14(9):383-7.
  • 2006
    Stadthagen G, Jackson M, Charles P, Boudou F, Barilone N, Huerre M, Constant P, Liav A, Bottova I, Nigou J, Brando T, Puzo G, Daffé M, Benjamin P, Coade S, Buxton RS, Tascon RE, Rae A, Robertson BD, Lowrie DB, Young DB, Gicquel B, Griffin R, Comparative investigation of the pathogenicity of three Mycobacterium tuberculosis mutants defective in the synthesis of p-hydroxybenzoic acid derivatives, Microbes Infect. 2006 Jul;8(8):2245-53.
  • 2006
    Martin C, Williams A, Hernandez-Pando R, Cardona PJ, Gormley E, Bordat Y, Soto CY, Clark SO, Hatch GJ, Aguilar D, Ausina V, Gicquel B, The live Mycobacterium tuberculosis phoP mutant strain is more attenuated than BCG and confers protective immunity against tuberculosis in mice and guinea pigs, Vaccine 2006 Apr;24(17):3408-19.
  • 2006
    Barreiro LB, Quach H, Krahenbuhl J, Khaliq S, Mohyuddin A, Mehdi SQ, Gicquel B, Neyrolles O, Quintana-Murci L, DC-SIGN interacts with Mycobacterium leprae but sequence variation in this lectin is not associated with leprosy in the Pakistani population, Hum. Immunol. 2006 Jan-Feb;67(1-2):102-7.
  • 2006
    Sulzenbacher G, Canaan S, Bordat Y, Neyrolles O, Stadthagen G, Roig-Zamboni V, Rauzier J, Maurin D, Laval F, Daffé M, Cambillau C, Gicquel B, Bourne Y, Jackson M, LppX is a lipoprotein required for the translocation of phthiocerol dimycocerosates to the surface of Mycobacterium tuberculosis, EMBO J. 2006 Apr;25(7):1436-44.
  • 2006
    Rosas-Magallanes V, Deschavanne P, Quintana-Murci L, Brosch R, Gicquel B, Neyrolles O, Horizontal transfer of a virulence operon to the ancestor of Mycobacterium tuberculosis, Mol. Biol. Evol. 2006 Jun;23(6):1129-35.
  • 2006
    Patin E, Barreiro LB, Sabeti PC, Austerlitz F, Luca F, Sajantila A, Behar DM, Semino O, Sakuntabhai A, Guiso N, Gicquel B, McElreavey K, Harding RM, Heyer E, Quintana-Murci L, Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes, Am. J. Hum. Genet. 2006 Mar;78(3):423-36.
  • 2006
    Barreiro LB, Neyrolles O, Babb CL, Tailleux L, Quach H, McElreavey K, Helden PD, Hoal EG, Gicquel B, Quintana-Murci L, Promoter variation in the DC-SIGN-encoding gene CD209 is associated with tuberculosis, PLoS Med. 2006 Feb;3(2):e20.
  • 2006
    Bourgarit A, Carcelain G, Martinez V, Lascoux C, Delcey V, Gicquel B, Vicaut E, Lagrange PH, Sereni D, Autran B, Explosion of tuberculin-specific Th1-responses induces immune restoration syndrome in tuberculosis and HIV co-infected patients, AIDS 2006 Jan;20(2):F1-7.
  • 2005
    Pitarque S, Herrmann JL, Duteyrat JL, Jackson M, Stewart GR, Lecointe F, Payre B, Schwartz O, Young DB, Marchal G, Lagrange PH, Puzo G, Gicquel B, Nigou J, Neyrolles O, Deciphering the molecular bases of Mycobacterium tuberculosis binding to the lectin DC-SIGN reveals an underestimated complexity, Biochem. J. 2005 Dec;392(Pt 3):615-24.
  • 2005
    Gonzalo Asensio J, Maia C, Ferrer NL, Barilone N, Laval F, Soto CY, Winter N, Daffé M, Gicquel B, Martín C, Jackson M, The virulence-associated two-component PhoP-PhoR system controls the biosynthesis of polyketide-derived lipids in Mycobacterium tuberculosis, J. Biol. Chem. 2006 Jan;281(3):1313-6.
  • 2005
    Tailleux L, Pham-Thi N, Bergeron-Lafaurie A, Herrmann JL, Charles P, Schwartz O, Scheinmann P, Lagrange PH, de Blic J, Tazi A, Gicquel B, Neyrolles O, DC-SIGN induction in alveolar macrophages defines privileged target host cells for mycobacteria in patients with tuberculosis, PLoS Med. 2005 Dec;2(12):e381.
  • 2005
    Dupont C, Thompson K, Heuer C, Gicquel B, Murray A, Identification and characterization of an immunogenic 22 kDa exported protein of Mycobacterium avium subspecies paratuberculosis, J. Med. Microbiol. 2005 Nov;54(Pt 11):1083-92.
  • 2005
    Stadthagen G, Korduláková J, Griffin R, Constant P, Bottová I, Barilone N, Gicquel B, Daffé M, Jackson M, p-Hydroxybenzoic acid synthesis in Mycobacterium tuberculosis, J. Biol. Chem. 2005 Dec;280(49):40699-706.
  • 2005
    Barreiro LB, Patin E, Neyrolles O, Cann HM, Gicquel B, Quintana-Murci L, The heritage of pathogen pressures and ancient demography in the human innate-immunity CD209/CD209L region, Am. J. Hum. Genet. 2005 Nov;77(5):869-86.
  • 2005
    Abadie V, Badell E, Douillard P, Ensergueix D, Leenen PJ, Tanguy M, Fiette L, Saeland S, Gicquel B, Winter N, Neutrophils rapidly migrate via lymphatics after Mycobacterium bovis BCG intradermal vaccination and shuttle live bacilli to the draining lymph nodes, Blood 2005 Sep;106(5):1843-50.
  • 2005
    Williams A, Hatch GJ, Clark SO, Gooch KE, Hatch KA, Hall GA, Huygen K, Ottenhoff TH, Franken KL, Andersen P, Doherty TM, Kaufmann SH, Grode L, Seiler P, Martin C, Gicquel B, Cole ST, Brodin P, Pym AS, Dalemans W, Cohen J, Lobet Y, Goonetilleke N, McShane H, Hill A, Parish T, Smith D, Stoker NG, Lowrie DB, Källenius G, Svenson S, Pawlowski A, Blake K, Marsh PD, Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis, Tuberculosis (Edinb) 2005 Jan-Mar;85(1-2):29-38.
  • 2005
    Wagner D, Maser J, Moric I, Boechat N, Vogt S, Gicquel B, Lai B, Reyrat JM, Bermudez L, Changes of the phagosomal elemental concentrations by Mycobacterium tuberculosis Mramp, Microbiology (Reading, Engl.) 2005 Jan;151(Pt 1):323-32.
  • 2005
    Brown N, Jacobs M, Parida SK, Botha T, Santos A, Fick L, Gicquel B, Jackson M, Quesniaux V, Ryffel B, Reduced local growth and spread but preserved pathogenicity of a DeltapurC Mycobacterium tuberculosis auxotrophic mutant in gamma interferon receptor-deficient mice after aerosol infection, Infect. Immun. 2005 Jan;73(1):666-70.
  • 2004
    Varaldo PB, Leite LC, Dias WO, Miyaji EN, Torres FI, Gebara VC, Armôa GR, Campos AS, Matos DC, Winter N, Gicquel B, Vilar MM, McFadden J, Almeida MS, Tendler M, McIntosh D, Recombinant Mycobacterium bovis BCG expressing the Sm14 antigen of Schistosoma mansoni protects mice from cercarial challenge, Infect. Immun. 2004 Jun;72(6):3336-43.
  • 2004
    Kocíncová D, Sondén B, Bordat Y, Pivert E, de Mendonça-Lima L, Gicquel B, Reyrat JM, The hydrophobic domain of the Mycobacterial Erp protein is not essential for the virulence of Mycobacterium tuberculosis, Infect. Immun. 2004 Apr;72(4):2379-82.
  • 2004
    Rousseau C, Winter N, Pivert E, Bordat Y, Neyrolles O, Avé P, Huerre M, Gicquel B, Jackson M, Production of phthiocerol dimycocerosates protects Mycobacterium tuberculosis from the cidal activity of reactive nitrogen intermediates produced by macrophages and modulates the early immune response to infection, Cell. Microbiol. 2004 Mar;6(3):277-87.
  • 2004
    Kocíncová D, Sondén B, de Mendonça-Lima L, Gicquel B, Reyrat JM, The Erp protein is anchored at the surface by a carboxy-terminal hydrophobic domain and is important for cell-wall structure in Mycobacterium smegmatis, FEMS Microbiol. Lett. 2004 Feb;231(2):191-6.
  • 2004
    Zganiacz A, Santosuosso M, Wang J, Yang T, Chen L, Anzulovic M, Alexander S, Gicquel B, Wan Y, Bramson J, Inman M, Xing Z, TNF-alpha is a critical negative regulator of type 1 immune activation during intracellular bacterial infection, J. Clin. Invest. 2004 Feb;113(3):401-13.
  • 2004
    Mazzantini RP, Miyaji EN, Dias WO, Sakauchi D, Nascimento AL, Raw I, Winter N, Gicquel B, Rappuoli R, Leite LC, Adjuvant activity of Mycobacterium bovis BCG expressing CRM197 on the immune response induced by BCG expressing tetanus toxin fragment C, Vaccine 2004 Jan;22(5-6):740-6.
  • 2003
    Pinto R, Saunders BM, Camacho LR, Britton WJ, Gicquel B, Triccas JA, Mycobacterium tuberculosis defective in phthiocerol dimycocerosate translocation provides greater protective immunity against tuberculosis than the existing bacille Calmette-Guérin vaccine, J. Infect. Dis. 2004 Jan;189(1):105-12.
  • 2003
    Méderlé I, Le Grand R, Vaslin B, Badell E, Vingert B, Dormont D, Gicquel B, Winter N, Mucosal administration of three recombinant Mycobacterium bovis BCG-SIVmac251 strains to cynomolgus macaques induces rectal IgAs and boosts systemic cellular immune responses that are primed by intradermal vaccination, Vaccine 2003 Oct;21(27-30):4153-66.
  • 2003
    Rousseau C, Turner OC, Rush E, Bordat Y, Sirakova TD, Kolattukudy PE, Ritter S, Orme IM, Gicquel B, Jackson M, Sulfolipid deficiency does not affect the virulence of Mycobacterium tuberculosis H37Rv in mice and guinea pigs, Infect. Immun. 2003 Aug;71(8):4684-90.
  • 2003
    Korduláková J, Gilleron M, Puzo G, Brennan PJ, Gicquel B, Mikusová K, Jackson M, Identification of the required acyltransferase step in the biosynthesis of the phosphatidylinositol mannosides of mycobacterium species, J. Biol. Chem. 2003 Sep;278(38):36285-95.
  • 2003
    Ebrahimi-Rad M, Bifani P, Martin C, Kremer K, Samper S, Rauzier J, Kreiswirth B, Blazquez J, Jouan M, van Soolingen D, Gicquel B, Mutations in putative mutator genes of Mycobacterium tuberculosis strains of the W-Beijing family, Emerging Infect. Dis. 2003 Jul;9(7):838-45.
  • 2003
    Rousseau C, Sirakova TD, Dubey VS, Bordat Y, Kolattukudy PE, Gicquel B, Jackson M, Virulence attenuation of two Mas-like polyketide synthase mutants of Mycobacterium tuberculosis, Microbiology (Reading, Engl.) 2003 Jul;149(Pt 7):1837-47.
  • 2003
    Recchi C, Sclavi B, Rauzier J, Gicquel B, Reyrat JM, Mycobacterium tuberculosis Rv1395 is a class III transcriptional regulator of the AraC family involved in cytochrome P450 regulation, J. Biol. Chem. 2003 Sep;278(36):33763-73.
  • 2003
    Rousseau C, Neyrolles O, Bordat Y, Giroux S, Sirakova TD, Prevost MC, Kolattukudy PE, Gicquel B, Jackson M, Deficiency in mycolipenate- and mycosanoate-derived acyltrehaloses enhances early interactions of Mycobacterium tuberculosis with host cells, Cell. Microbiol. 2003 Jun;5(6):405-15.
  • 2003
    Tailleux L, Gicquel B, Neyrolles O, [DC-SIGN, a key receptor of Mycobacterium tuberculosis?], Med Sci (Paris) 2003 Jun-Jul;19(6-7):658-60.
  • 2003
    Tailleux L, Maeda N, Nigou J, Gicquel B, Neyrolles O, How is the phagocyte lectin keyboard played? Master class lesson by Mycobacterium tuberculosis, Trends Microbiol. 2003 Jun;11(6):259-63.
  • 2003
    Jiao X, Lo-Man R, Winter N, Dériaud E, Gicquel B, Leclerc C, The shift of Th1 to Th2 immunodominance associated with the chronicity of Mycobacterium bovis bacille Calmette-Guérin infection does not affect the memory response, J. Immunol. 2003 Feb;170(3):1392-8.
  • 2003
    de Mendonça-Lima L, Bordat Y, Pivert E, Recchi C, Neyrolles O, Maitournam A, Gicquel B, Reyrat JM, The allele encoding the mycobacterial Erp protein affects lung disease in mice, Cell. Microbiol. 2003 Jan;5(1):65-73.
  • 2003
    Tailleux L, Schwartz O, Herrmann JL, Pivert E, Jackson M, Amara A, Legres L, Dreher D, Nicod LP, Gluckman JC, Lagrange PH, Gicquel B, Neyrolles O, DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells, J. Exp. Med. 2003 Jan;197(1):121-7.
  • 2002
    Maeda N, Nigou J, Herrmann JL, Jackson M, Amara A, Lagrange PH, Puzo G, Gicquel B, Neyrolles O, The cell surface receptor DC-SIGN discriminates between Mycobacterium species through selective recognition of the mannose caps on lipoarabinomannan, J. Biol. Chem. 2003 Feb;278(8):5513-6.
  • 2002
    Rasolofo Razanamparany V, Ménard D, Aurégan G, Gicquel B, Chanteau S, Extrapulmonary and pulmonary tuberculosis in antananarivo (madagascar): high clustering rate in female patients, J. Clin. Microbiol. 2002 Nov;40(11):3964-9.
  • 2002
    Ludwiczak P, Gilleron M, Bordat Y, Martin C, Gicquel B, Puzo G, Mycobacterium tuberculosis phoP mutant: lipoarabinomannan molecular structure, Microbiology (Reading, Engl.) 2002 Oct;148(Pt 10):3029-37.
  • 2002
    Boechat N, Lagier-Roger B, Petit S, Bordat Y, Rauzier J, Hance AJ, Gicquel B, Reyrat JM, Disruption of the gene homologous to mammalian Nramp1 in Mycobacterium tuberculosis does not affect virulence in mice, Infect. Immun. 2002 Aug;70(8):4124-31.
  • 2002
    Raynaud C, Guilhot C, Rauzier J, Bordat Y, Pelicic V, Manganelli R, Smith I, Gicquel B, Jackson M, Phospholipases C are involved in the virulence of Mycobacterium tuberculosis, Mol. Microbiol. 2002 Jul;45(1):203-17.
  • 2002
    Korduláková J, Gilleron M, Mikusova K, Puzo G, Brennan PJ, Gicquel B, Jackson M, Definition of the first mannosylation step in phosphatidylinositol mannoside synthesis. PimA is essential for growth of mycobacteria, J. Biol. Chem. 2002 Aug;277(35):31335-44.
  • 2002
    Puech V, Guilhot C, Perez E, Tropis M, Armitige LY, Gicquel B, Daffé M, Evidence for a partial redundancy of the fibronectin-binding proteins for the transfer of mycoloyl residues onto the cell wall arabinogalactan termini of Mycobacterium tuberculosis, Mol. Microbiol. 2002 May;44(4):1109-22.
  • 2002
    Ewann F, Jackson M, Pethe K, Cooper A, Mielcarek N, Ensergueix D, Gicquel B, Locht C, Supply P, Transient requirement of the PrrA-PrrB two-component system for early intracellular multiplication of Mycobacterium tuberculosis, Infect. Immun. 2002 May;70(5):2256-63.
  • 2002
    Recchi C, Rauzier J, Gicquel B, Reyrat JM, Signal-sequence-independent secretion of the staphylococcal nuclease in Mycobacterium smegmatis, Microbiology (Reading, Engl.) 2002 Feb;148(Pt 2):529-36.
  • 2002
    Jiao X, Lo-Man R, Guermonprez P, Fiette L, Dériaud E, Burgaud S, Gicquel B, Winter N, Leclerc C, Dendritic cells are host cells for mycobacteria in vivo that trigger innate and acquired immunity., J Immunol 2002 Feb; 168(3): 1294-301.
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