Présentation
Methods of diagnosing a spondylarthritis (SpA) or a likelihood of having or developing an SpA ina subjectare provided. The methods may comprise performing a genotyping assay of (i) at least one first SNP locus linked to a first gene selected from IL23R, IL12B, STAT3, STAT4, and CCR6, and (ii) at least one second SNP locus linked to a second gene selected from IL23R, IL12B, STAT3, STAT4, and CCR6. Methodsof treating or preventing an SpA in a subjectare also provided. The methods may comprise performing a genotyping assay of (i) at least one first SNP locus linked to a first gene selected from IL23R, IL12B, STAT3, STAT4, and CCR6, and (ii) at least one second SNP locus linked to a second gene selected from IL23R, IL12B, STAT3, STAT4, and CCR6. Kits for performing the genotyping assays are also provided.