Circulating biomarkers in geographically diverse populations with varying rates of gastric cancer
Gastric cancer is the fourth most common malignancy and the third cause of cancer related-death worldwide. Although its incidence and mortality rates have progressively decreased in the last decades, the absolute number of cases […]
Upstream stimulating factors USF1 and USF2 in the host response to Helicobacter pylori infection : impact on gastric carcinogenesis
The usptream stimulating factors USF1 and USF2 are pleïotropic transcription factors belong to the bHLH-Zip family as the oncogene c-Myc. They act as homo- or heterodimers and interact with DNA consensus E-box sequences in […]
Method for in vitro investigating mitochondrial DNA levels in a biological sample, kit and uses thereof
The invention relates to an in vitro method for investigating the level of mtDNA in a biological sample removed from a patient susceptible of suffering from a gastric cancer condition or susceptible of suffering […]
2021A novel mode of control of nickel uptake by a multifunctional metallochaperone., PLoS Pathog 2021 01; 17(1): e1009193.
2019Design, Synthesis, and Efficacy Testing of Nitroethylene- and 7-Nitrobenzoxadiazol-Based Flavodoxin Inhibitors against Helicobacter pylori Drug-Resistant Clinical Strains and in Helicobacter pylori-Infected Mice., J Med Chem 2019 07; 62(13): 6102-6115.
2018Effect of Helicobacter pylori Infection on GATA-5 and TFF1 Regulation, Comparison Between Pediatric and Adult Patients, Dig. Dis. Sci. 2018 11;63(11):2889-2897.
2017Helicobacter pylori targets mitochondrial import and components of mitochondrial DNA replication machinery through an alternative VacA-dependent and a VacA-independent mechanisms., Sci Rep 2017 Nov; 7(1): 15901.
2017Colonization with Helicobacter is concomitant with modified gut microbiota and drastic failure of the immune control of Mycobacterium tuberculosis, Mucosal Immunol 2017 Sep;10(5):1178-1189.
2016Characterization in Helicobacter pylori of a Nickel Transporter Essential for Colonization That Was Acquired during Evolution by Gastric Helicobacter Species, PLoS Pathog. 2016 Dec;12(12):e1006018.
2015Evolution of Helicobacter: Acquisition by Gastric Species of Two Histidine-Rich Proteins Essential for Colonization, PLoS Pathog 11(12): e1005312. doi:10.1371/journal. ppat.1005312.
2014Circulating mitochondrial DNA level, a noninvasive biomarker for the early detection of gastric cancer, Cancer Epidemiol. Biomarkers Prev. 2014 Nov;23(11):2430-8.
2013Crosstalk between Helicobacter pylori and gastric epithelial cells is impaired by docosahexaenoic acid., PLoS One. 2013;8(4):e60657. doi: 10.1371/journal.pone.0060657.