Thomas Vial

I’m currently a postdoctoral researcher in the Insect Immunity & Infection group within the Virology Department and the Insect-Virus Interactions Unit. We aim to understand the interactions between Aedes aegypti mosquitoes and the arboviruses they transmit to humans (i.e. dengue virus, Zika virus and Chikungunya virus). My research focuses particularly on understanding the molecular mechanisms behind the natural resistance or susceptibility of field-derived mosquito colonies to dengue viruses, using approaches that combine metabolomics and single-cell omics. 

Academic education

2017-2020      PhD Degree in Virology, Université Toulouse III, Paul Sabatier, France / Duke-NUS Medical School, Singapore

2008-2010      Master Degree in Cellular and Molecular biology, Université Pierre et Marie Curie, Paris IV, France

2005-2008      Bachelor Degree in Microbiology, Université Claude Bernard, Lyon 1, France

Research experience

Since January 2022  Post-doctoral researcher within the Interactions Virus-Insect Unit, Virology department, Institut Pasteur, CNRS UMR 2000

November 2020 – November 2021  Post-doctoral researcher Department of pathology, Division of Virology, University of Cambridge, Cambridge, United-Kingdom /AMC Medical Research, Amsterdam UMC, Amsterdam, Netherland. Supervisor: Dr. AJ te Velthius, Project: Study of emerging mutations and inhibitors impact on coronavirus replication by the establishment of a virus-free high-throughput platform.

September 2017 – June 2020  PhD student Duke-NUS Medical Shool, Singapore / PharmaDev, Faculté de pharmacie, Université de Touloue 3, France. Supervisor: Dr. Julien Pompon / Dr. Eric Deharo/ Dr. Guillaume Marti. Project: Study of the metabolic interactions between Dengue virus and mosquitoes using a metabolomic approach to identify host targets in order to limit viral transmission

January 2016 – December 2017  Scientific cooperation officer Institut de Recherche pour le Développement (IRD), Vientiane, Laos. Supervisor: Dr. Eric Deharo. Project: Coordination of interdisciplinary research projects on emerging infectious diseases in Laos, Singapore and Colombia.

March 2012- December 2015 Project manager / Immunology Team Leader Diagnostica Stago, Paris, France. Project: In charge of the development of the immunological reagent for the diagnosis of venous thromboembolic diseases.

Januray 2010- December 2011  Master – 2nd research internship / Research Associate in Virology Sanofi-Pasteur, Lyon, France. Project: Study the attenuation of flavivirus vaccine strains and immunization potential of vaccine candidates.

January – March 2009  Master – 1st research internship GIMAP, Université de Saint-Etienne, France. Supervisor: Dr. Bruno Pozetto. Project: In vitro evaluation of the benefit-risk effects of anti-HIV microbicides under vaginal epithelium.

Fellowships and Awards

2023 ACME Postdoc Travel Award

2023 Marie Skłodowska-Curie Actions Postdoctoral Fellowship

2022 Pasteur-Roux Post-doctoral Fellowship Grant

2018 PHC Merlion travel grant NUS Singapore – France

Publications

Link pubmed: https://pubmed.ncbi.nlm.nih.gov/?term=Vial+Thomas