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FP7 Targeting the Leishmania kinome for the development of novel anti-parasitic strategies (LeishDrug)
Gérald Spaeth (PI)
Visceral leishmaniasis is caused by the protozoan parasites Leishmania donovani and Leishmania infantum and is a potentially fatal disease in endemic areas around the world. During the infectious cycle, Leishmania alternate between the insect […]
2020Leishmania amazonensis Subverts the Transcription Factor Landscape in Dendritic Cells to Avoid Inflammasome Activation and Stall Maturation, Front Immunol . 2020 Jun 9;11:1098.
2020Targeting Macrophage Histone H3 Modification as a Leishmania Strategy to Dampen the NF-κB/NLRP3-Mediated Inflammatory Response., Cell Rep 2020 Feb; 30(6): 1870-1882.e4.
2013A combined luciferase-expressing Leishmania imaging/RT-qPCR assay provides new insights into the sequential bilateral processes deployed in the ear pinna of C57BL/6 mice, Parasitol. Int. 2014 Feb;63(1):245-53.
2008Retention of Plasmodium falciparum ring-infected erythrocytes in the slow, open microcirculation of the human spleen, Blood 2008 Sep;112(6):2520-8.
2005Ex vivo perfusion of human spleens maintains clearing and processing functions, Blood 2006 May;107(9):3745-52.