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(EN) I hold an engineering degree from Ecole Polytechnique and a PhD in applied mathematics from Université Pierre et Marie Curie.
During my PhD in computational biology at Inria Paris, my main topic was to investigate in-silico the molecular mechanisms behind the resistance of cancer cells to the death ligand TRAIL. To do that, I developped a cell-based (each cell is represented individually) multi-scale (cellular decisions are controlled by biochemical reaction pathways simulated in each cell) approach to model the dynamics of cell populations.
I then moved to Imperial College for a 2.5 years post-doc, where I started to do experiments, investigating physiology of fission yeast at the single-cell level.
2022Enabling Reactive Microscopy with MicroMator, Nat. Commun. 2022; 13:2199.
2022Enabling reactive microscopy with MicroMator., Nat Commun 2022 Apr; 13(1): 2199.
2022Using single-cell models to predict the functionality of synthetic circuits at the population scale, Proc Natl Acad Sci U S A 2022 Mar; 119(11): e2114438119.
2021External control of microbial populations for bioproduction: A modeling and optimization viewpoint, Current Opinion in Systems Biology. 2021 Dec 1;28:100394.
2021A light tunable differentiation system for the creation and control of consortia in yeast, Nat Commun 2021 10; 12(1): 5829.
2020Enhancing bioreactor arrays for automated measurements and reactive control with ReacSight, BioRxiv.
2020A bacterial size law revealed by a coarse-grained model of cell physiology, PLoS Comput Biol 2020 09; 16(9): e1008245.