Présentation
Bacterial pathogens are facing fierce conditions to colonize their host and launch successful infections. Not only they have to escape the immune system but they should also compete with other invading organisms or resident bacterial flora. This warfare is crucial for winning access to sometime scarce resources such as iron or other essential nutriments which will sustain growth and survival. These pathogens employ a variety of strategies which are associated with canonical lifestyles. Here we will discuss how Pseudomonas aeruginosa uses a bacterial weapon called the type VI secretion system (T6SS) to eliminate competitors.There are multi examples of bacterial toxins, which are transported in a T6SS-dependent manner, and P. aeruginosa can use a remarkable collection of ammunitions, which make it a resilient and potent competitor when facing other organisms. We will discuss the kind of T6SS toxins that are injected into bacterial preys and how they can point at the identification of new antimicrobial targets which could be used for drug development
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Localisation
Bâtiment: Centre François Jacob
Adresse: 28 Rue du Docteur Roux, Paris, France
(function($) {
/*
* render_map
*
* This function will render a Google Map onto the selected jQuery element
*
* @type function
* @date 8/11/2013
* @since 4.3.0
*
* @param $el (jQuery element)
* @return n/a
*/
function render_map( $el ) {
var MY_MAPTYPE_ID = 'custom_style';
var featureOpts = [{"stylers":[{"hue":"#0088ff"}]}];
var styledMapOptions = {
name: 'Custom Style'
};
var customMapType = new google.maps.StyledMapType(featureOpts, styledMapOptions);
// var
var $markers = $el.find('.marker');
// vars
var args = {
zoom : 16,
scrollwheel : false,
center : new google.maps.LatLng(0, 0),
mapTypeId : google.maps.MapTypeId.ROADMAP,
mapTypeId : MY_MAPTYPE_ID
};
// create map
var map = new google.maps.Map( $el[0], args);
map.mapTypes.set(MY_MAPTYPE_ID, customMapType);
// add a markers reference
map.markers = [];
// add markers
$markers.each(function(){
add_marker( $(this), map );
});
// center map
center_map( map );
}
/*
* add_marker
*
* This function will add a marker to the selected Google Map
*
* @type function
* @date 8/11/2013
* @since 4.3.0
*
* @param $marker (jQuery element)
* @param map (Google Map object)
* @return n/a
*/
function add_marker( $marker, map ) {
// var
var latlng = new google.maps.LatLng( $marker.attr('data-lat'), $marker.attr('data-lng') );
//var image = 'https://research.pasteur.fr/wp-content/themes/biologyx2/images/logomap.png';
var myIcon = new google.maps.MarkerImage('https://research.pasteur.fr/wp-content/themes/biologyx2/images/map-pin.png', null, null, null, new google.maps.Size(32,32));
// create marker
var marker = new google.maps.Marker({
position : latlng,
map : map,
icon : myIcon
});
// add to array
map.markers.push( marker );
// if marker contains HTML, add it to an infoWindow
if( $marker.html() )
{
// create info window
var infowindow = new google.maps.InfoWindow({
content : $marker.html()
});
// show info window when marker is clicked
google.maps.event.addListener(marker, 'click', function() {
infowindow.open( map, marker );
});
}
}
/*
* center_map
*
* This function will center the map, showing all markers attached to this map
*
* @type function
* @date 8/11/2013
* @since 4.3.0
*
* @param map (Google Map object)
* @return n/a
*/
function center_map( map ) {
// vars
var bounds = new google.maps.LatLngBounds();
// loop through all markers and create bounds
$.each( map.markers, function( i, marker ){
var latlng = new google.maps.LatLng( marker.position.lat(), marker.position.lng() );
bounds.extend( latlng );
});
// only 1 marker?
if( map.markers.length == 1 )
{
// set center of map
map.setCenter( bounds.getCenter() );
map.setZoom( 15 );
}
else
{
// fit to bounds
map.fitBounds( bounds );
}
}
/*
* document ready
*
* This function will render each map when the document is ready (page has loaded)
*
* @type function
* @date 8/11/2013
* @since 5.0.0
*
* @param n/a
* @return n/a
*/
$(document).ready(function(){
$('.acf-map').each(function(){
render_map( $(this) );
});
});
})(jQuery);