Présentation
Microglia are extremely specialized immune cells, which reside in the CNS and play key roles in its development, homeostasis and disease. Such specialization is imposed by the peculiar environment the microglia have to live in; separated from other immune cells, bathed by interstitial fluid of the CNS and staying in constant contact with electrically active neurons and glia. Our goal is to reveal molecular circuits shaping microglial identity, and understanding how microglia shape the CNS in response.