Présentation
We developed a clinically relevant in vivo model of catheter-associated biofilm infections to design new and efficient biofilm-eradication approaches applicable to contaminated totally implantable venous access port (TIVAP) catheters.
Key publications
• Chauhan, A., J.M. Ghigo, and C. Beloin. (2016). Study of in vivo catheter biofilm infections using pediatric central venous catheter implanted in rat. Nature Protocols Mar;11(3):525-41. doi: 10.1038/nprot.2016.033.
• Chauhan A., D. Lebeaux, J.M. Ghigo, and C. Beloin. (2012). Full and broad-spectrum in vivo eradication of catheter-associated biofilms using Gentamicin-EDTA antibiotic lock therapy. Antimicrobial Agents and Chemotherapy 56(12):6310-8. doi: 10.1128.