Blunted response to combination antiretroviral therapy in HIV elite controllers: an international HIV controller collaboration

Lien vers Pubmed [PMID] – 24465584

PLoS ONE 2014;9(1):e85516

HIV “elite controllers” (ECs) spontaneously control viral load, but some eventually require combination antiretroviral treatment (cART), due to a loss of viral control or a decline in CD4 T-cell counts. Here we studied the CD4 T-cell count dynamics after cART initiation among 34 ECs followed in U.S. and European cohorts, by comparison with chronically viremic patients (VIRs).