Timeline

Han Li
Head of Structure
18 Sep 2020
event

PhD Thesis Defense: “Dissecting the Impact of Cellular Senescence on Muscle Regeneration”

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18 Nov 2019
event

PhD Defense – Mathieu Von Joest: “Dissecting the Non-Cell Autonomous Impact of Cellular Senescence on Cellular Reprogramming”.

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18 Nov 2019
event

HDR Defense: Han Li, “Cellular Plasticity in Cancer and Ageing”

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01 Apr 2019
project

Organ-on-Chip Center

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01 Jan 2019
publication

Detecting Cellular Senescence in Reprogramming

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27 Feb 2018
event

Department seminar by Amar Deep Sharma, MHH, Hannover, Germany: “Regenerative Medicine for the Dysfunctional Liver”

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26 Oct 2017
publication

Evaluation of Injury-induced Senescence and In Vivo Reprogramming in the Skeletal Muscle

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01 Jun 2017
publication

Δ133p53 represses p53-inducible senescence genes and enhances the generation of human induced pluripotent stem cells

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09 Mar 2017
event

SEMINAR ” Epigenetic mechanisms in early mammalian development ” by Maria Elena Torres-Padilla

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22 Dec 2016
publication

Injury-Induced Senescence Enables In Vivo Reprogramming in Skeletal Muscle

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01 Jun 2016
publication

Genomic stability during cellular reprogramming: Mission impossible? Mutat Res. 2016 Jun;788:12-6,

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01 Aug 2015
publication

Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells

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09 Jun 2015
project

Cellular plasticity and Ageing

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09 Jun 2015
project

Cellular plasticity and Cancer

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11 May 2015
team

Cellular Plasticity And Disease Modelling

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23 Jan 2014
publication

Deletion of individual Ku subunits in mice causes an NHEJ-independent phenotype potentially by altering apurinic/apyrimidinic site repair

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10 Jun 2013
publication

Reprogramming activity of NANOGP8, a NANOG family member widely expressed in cancer

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06 Apr 2013
publication

Ku80-deleted cells are defective at base excision repair

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01 Dec 2012
publication

p27(Kip1) directly represses Sox2 during embryonic stem cell differentiation

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10 Nov 2011
publication

Increased dosage of tumor suppressors limits the tumorigenicity of iPS cells without affecting their pluripotency

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05 May 2011
publication

Trex2 enables spontaneous sister chromatid exchanges without facilitating DNA double-strand break repair

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01 May 2011
publication

Epigenetic regulation of Nanog expression by Ezh2 in pluripotent stem cells

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21 Oct 2010
publication

SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53

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09 Aug 2009
publication

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

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09 Aug 2009
publication

The Ink4/Arf locus is a barrier for iPS cell reprogramming

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30 Mar 2009
publication

Deleting Ku70 is milder than deleting Ku80 in p53-mutant mice and cells

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01 Feb 2009
publication

Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells

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14 Feb 2008
publication

DNA double-strand breaks: a potential causative factor for mammalian aging?

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17 Sep 2007
publication

Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer

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21 Sep 2005
publication

Non-homologous end joining, but not homologous recombination, enables survival for cells exposed to a histone deacetylase inhibitor

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01 Oct 2004
publication

A genotoxic screen: rapid analysis of cellular dose-response to a wide range of agents that either damage DNA or alter genome maintenance pathways

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