Timeline

Han Li

Head of Structure

22 Jan 2026

event

Women’s Health, Women in Health

17 Dec 2025

publication

In vivo risk assessment of yellow fever virus transmission through breastfeeding, and mechanistic insights.

01 Feb 2023

publication

Systemic GDF11 attenuates depression-like phenotype in aged mice via stimulation of neuronal autophagy.

12 Jul 2022

publication

Amphiregulin mediates non-cell-autonomous effect of senescence on reprogramming.

01 Apr 2019

project

Organ-on-Chip Center

01 Jan 2019

publication

Detecting Cellular Senescence in Reprogramming

26 Oct 2017

publication

Evaluation of Injury-induced Senescence and In Vivo Reprogramming in the Skeletal Muscle

01 Jun 2017

publication

Δ133p53 represses p53-inducible senescence genes and enhances the generation of human induced pluripotent stem cells

22 Dec 2016

publication

Injury-Induced Senescence Enables In Vivo Reprogramming in Skeletal Muscle

01 Jun 2016

publication

Genomic stability during cellular reprogramming: Mission impossible? Mutat Res. 2016 Jun;788:12-6,

01 Aug 2015

publication

Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells

11 May 2015

team

Cellular plasticity in age-related pathologies

23 Jan 2014

publication

Deletion of individual Ku subunits in mice causes an NHEJ-independent phenotype potentially by altering apurinic/apyrimidinic site repair

10 Jun 2013

publication

Reprogramming activity of NANOGP8, a NANOG family member widely expressed in cancer

06 Apr 2013

publication

Ku80-deleted cells are defective at base excision repair

01 Dec 2012

publication

p27(Kip1) directly represses Sox2 during embryonic stem cell differentiation

10 Nov 2011

publication

Increased dosage of tumor suppressors limits the tumorigenicity of iPS cells without affecting their pluripotency

05 May 2011

publication

Trex2 enables spontaneous sister chromatid exchanges without facilitating DNA double-strand break repair

01 May 2011

publication

Epigenetic regulation of Nanog expression by Ezh2 in pluripotent stem cells

21 Oct 2010

publication

SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53

09 Aug 2009

publication

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

09 Aug 2009

publication

The Ink4/Arf locus is a barrier for iPS cell reprogramming

30 Mar 2009

publication

Deleting Ku70 is milder than deleting Ku80 in p53-mutant mice and cells

01 Feb 2009

publication

Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells

14 Feb 2008

publication

DNA double-strand breaks: a potential causative factor for mammalian aging?

17 Sep 2007

publication

Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer

21 Sep 2005

publication

Non-homologous end joining, but not homologous recombination, enables survival for cells exposed to a histone deacetylase inhibitor

01 Oct 2004

publication

A little guide for advanced search:

Timeline

Women’s Health, Women in Health

In vivo risk assessment of yellow fever virus transmission through breastfeeding, and mechanistic insights.

Systemic GDF11 attenuates depression-like phenotype in aged mice via stimulation of neuronal autophagy.

Amphiregulin mediates non-cell-autonomous effect of senescence on reprogramming.

Organ-on-Chip Center

Detecting Cellular Senescence in Reprogramming

Evaluation of Injury-induced Senescence and In Vivo Reprogramming in the Skeletal Muscle

Δ133p53 represses p53-inducible senescence genes and enhances the generation of human induced pluripotent stem cells

Injury-Induced Senescence Enables In Vivo Reprogramming in Skeletal Muscle

Genomic stability during cellular reprogramming: Mission impossible? Mutat Res. 2016 Jun;788:12-6,

Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells

Cellular plasticity in age-related pathologies

Deletion of individual Ku subunits in mice causes an NHEJ-independent phenotype potentially by altering apurinic/apyrimidinic site repair

Reprogramming activity of NANOGP8, a NANOG family member widely expressed in cancer

Ku80-deleted cells are defective at base excision repair

p27(Kip1) directly represses Sox2 during embryonic stem cell differentiation

Increased dosage of tumor suppressors limits the tumorigenicity of iPS cells without affecting their pluripotency

Trex2 enables spontaneous sister chromatid exchanges without facilitating DNA double-strand break repair

Epigenetic regulation of Nanog expression by Ezh2 in pluripotent stem cells

SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

The Ink4/Arf locus is a barrier for iPS cell reprogramming

Deleting Ku70 is milder than deleting Ku80 in p53-mutant mice and cells

Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells

DNA double-strand breaks: a potential causative factor for mammalian aging?

Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer

Non-homologous end joining, but not homologous recombination, enables survival for cells exposed to a histone deacetylase inhibitor

A genotoxic screen: rapid analysis of cellular dose-response to a wide range of agents that either damage DNA or alter genome maintenance pathways