Timeline
Catherine Van Renterghem-Lalan
Permanent Researcher
01 Feb 2024
publication
Short-chain mono-carboxylates as negative modulators of allosteric transitions in Gloeobacter violaceus ligand-gated ion channel, and impact of a pre-β5 strand (Loop Ω) double mutation on crotonate, not butyrate effect.
Read more07 Apr 2023
publication
Fumarate as positive modulator of allosteric transitions in the pentameric ligand-gated ion channel GLIC: Requirement of an intact vestibular pocket.
Read more09 Apr 2018
publication
Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation
Read more27 Dec 2017
publication
Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel
Read more12 Feb 2013
publication
Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels
Read more13 May 2012
publication
A locally closed conformation of a bacterial pentameric proton-gated ion channel
Read more20 Jan 2011
publication
X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel
Read more22 Mar 2010
publication
One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue
Read more07 Dec 2009
publication