Timeline

Catherine Van Renterghem-Lalan
Permanent Researcher
01 Feb 2024
publication

Short-chain mono-carboxylates as negative modulators of allosteric transitions in Gloeobacter violaceus ligand-gated ion channel, and impact of a pre-β5 strand (Loop Ω) double mutation on crotonate, not butyrate effect.

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07 Apr 2023
publication

Fumarate as positive modulator of allosteric transitions in the pentameric ligand-gated ion channel GLIC: Requirement of an intact vestibular pocket.

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09 Apr 2018
publication

Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation

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27 Dec 2017
publication

Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel

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12 Feb 2013
publication

Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels

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13 May 2012
publication

A locally closed conformation of a bacterial pentameric proton-gated ion channel

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20 Jan 2011
publication

X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel

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22 Mar 2010
publication

One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue

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07 Dec 2009
publication

Atomic structure and dynamics of pentameric ligand-gated ion channels: new insight from bacterial homologues

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