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© Research
Publication : Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology

Why actively promote vaccination in patients with cirrhosis?

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 04 Jun 2009

Loulergue P, Pol S, Mallet V, Sogni P, Launay O,

Link to Pubmed [PMID] – 19501019

J. Clin. Virol. 2009 Nov;46(3):206-9

Patients with cirrhosis are immunocompromised and have an increased risk of infection, with a worse outcome. Some of those infections may be prevented by vaccination. Immunization can reduce the morbidity and mortality associated with cirrhosis. Immunizations against hepatitis A and B viruses, influenza and pneumococcus are recommended by the French Haute Autorité de Santé since 2007. Vaccination against hepatitis A is recommended in non-immunized cirrhotic patients. Vaccination against hepatitis B is recommended in every cirrhotic patient with no serological markers, and post-vaccinal antibodies titer should be checked. Annual influenza immunization can be done in cirrhotic patients, and pneumococcal polysaccharide vaccine should be repeated after 3-5 years. Few data regarding vaccination coverage are available, but studies suggest that immunization rates are too low in this population.

https://www.ncbi.nlm.nih.gov/pubmed/19501019