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© Christelle Durand
Microscopie d'un neurone. Le marquage jaune montre les synapses.
Publication : Journal of autism and developmental disorders

Vitamin d in the general population of young adults with autism in the faroe islands

Team: Human Genetics and Cognitive Functions
Member: Thomas Bourgeron
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of autism and developmental disorders - 01 Dec 2014

Kočovská E, Andorsdóttir G, Weihe P, Halling J, Fernell E, Stóra T, Biskupstø R, Gillberg IC, Shea R, Billstedt E, Bourgeron T, Minnis H, Gillberg C

Link to Pubmed [PMID] – 24927807

J Autism Dev Disord 2014 Dec;44(12):2996-3005

Vitamin D deficiency has been proposed as a possible risk factor for developing autism spectrum disorder (ASD). 25-Hydroxyvitamin D3 (25(OH)D3) levels were examined in a cross-sectional population-based study in the Faroe Islands. The case group consisting of a total population cohort of 40 individuals with ASD (aged 15-24 years) had significantly lower 25(OH)D3 than their 62 typically-developing siblings and their 77 parents, and also significantly lower than 40 healthy age and gender matched comparisons. There was a trend for males having lower 25(OH)D3 than females. Effects of age, month/season of birth, IQ, various subcategories of ASD and Autism Diagnostic Observation Schedule score were also investigated, however, no association was found. The very low 25(OH)D3 in the ASD group suggests some underlying pathogenic mechanism.