Link to Pubmed [PMID] – 22710276
Microbes Infect. 2012 Dec;14(15):1428-41
Human infections with Entamoeba histolytica sporadically become pathogenic, unknown triggers converting the parasite to its invasive phenotype. Parasite virulence results from complex host-parasite interactions implicating multiple amoebic and host factors, eliciting host defence responses and parasite resistance to stress caused by the host reactions and changing environments during tissue invasion.