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© Research
Publication : Critical care (London, England)

Translocation of bacterial NOD2 agonist and its link with inflammation

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Critical care (London, England) - 28 Jul 2009

Kim OY, Monsel A, Bertrand M, Cavaillon JM, Coriat P, Adib-Conquy M

Link to Pubmed [PMID] – 19638210

Crit Care 2009;13(4):R124

The gut is often considered as the motor of critical illness through bacterial translocation, which amplifies the inflammatory response and alters the immune status. However, systemic bacterial translocation was rarely proven and endotoxin measurement only reflects translocation of Gram-negative-derived products. The process could be more frequently identified if peptidoglycan, derived from both Gram-negative and Gram-positive bacteria, was measured.

http://www.ncbi.nlm.nih.gov/pubmed/19638210