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© Research
Publication : Plant signaling & behavior

Toward a unified model of the action of CLP/HSP100 chaperones in chloroplasts

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Plant signaling & behavior - 14 May 2012

Rosano GL, Bruch EM, Colombo CV, Ceccarelli EA

Link to Pubmed [PMID] – 22580704

Plant Signal Behav 2012 Jun;7(6):672-4

In chloroplasts, Hsp70 and Hsp100 chaperones have been long suspected to be the motors that provide the necessary energy for the import of precursor proteins destined to the organelle. The chaperones associate with the import translocon and meet the transit peptides as they emerge through the channel. After decades of active research, recent findings demonstrated that Hsp100 chaperones recognize transit peptides both in vitro and in vivo. Moreover, Hsp70 also plays a part in precursor import. The updated model of protein translocation into chloroplasts now presents new questions about the role of the chaperones in the process.

http://www.ncbi.nlm.nih.gov/pubmed/22580704