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© Institut Pasteur
Macrophages et lymphocytes de souris. Image colorisée.
Publication : Stem cell research & therapy

Three-dimensional spheroid cell culture of umbilical cord tissue-derived mesenchymal stromal cells leads to enhanced paracrine induction of wound healing

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Stem cell research & therapy - 09 May 2015

Santos JM, Camões SP, Filipe E, Cipriano M, Barcia RN, Filipe M, Teixeira M, Simões S, Gaspar M, Mosqueira D, Nascimento DS, Pinto-do-Ó P, Cruz P, Cruz H, Castro M, Miranda JP

Link to Pubmed [PMID] – 25956381

Stem Cell Res Ther 2015;6:90

The secretion of trophic factors by mesenchymal stromal cells has gained increased interest given the benefits it may bring to the treatment of a variety of traumatic injuries such as skin wounds. Herein, we report on a three-dimensional culture-based method to improve the paracrine activity of a specific population of umbilical cord tissue-derived mesenchymal stromal cells (UCX®) towards the application of conditioned medium for the treatment of cutaneous wounds.

http://www.ncbi.nlm.nih.gov/pubmed/25956381