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© Marie Prévost, Institut Pasteur
Image of a portion of a Xenopus oocyte expressing a channel receptor.
Publication : BioMed research international

The sequential tissue distribution of duck Tembusu virus in adult ducks

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in BioMed research international - 18 Aug 2014

Wu L, Liu J, Chen P, Jiang Y, Ding L, Lin Y, Li Q, He X, Chen Q, Chen H

Link to Pubmed [PMID] – 25215289

Biomed Res Int 2014;2014:703930

In 2010, a novel Tembusu virus (TMUV) that caused a severe decrease in the egg production of ducks was isolated in southeast China. Given the novelty of this duck pathogen, little information is available regarding its pathogenesis. Here, we systematically investigated the replication kinetics of TMUV PTD2010 in adult male and female ducks. We found that PTD2010 was detectable in most of the parenchymatous organs as well as the oviduct and intestinal tract from days 1 to 7 after inoculation. Viral titers were maintained at high levels for at least 9 days in the spleen, kidney, bursa of Fabricius, brain, and ovary. No virus was detected in any of these organs or tissues at 18 days after inoculation. PTD2010, thus, causes systemic infections in male and female ducks; its replication kinetics show similar patterns in most organs, with the exception of the ovaries and testes.

https://www.ncbi.nlm.nih.gov/pubmed/25215289