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© Perrine Bomme, Guillaume Duménil, Jean-Marc Panaud.
Coloured scanning electron micrograph (SEM) of Neisseria meningitidis on epithelial cells
Publication : Trends in microbiology

The duality of virulence and transmissibility in Neisseria meningitidis.

Team: Invasive Bacterial Infections
Member: Muhamed-Kheir Taha
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Trends in microbiology - 01 Aug 2002

Taha MK, Deghmane AE, Antignac A, Zarantonelli ML, Larribe M, Alonso JM,

Link to Pubmed [PMID] – 12160636

Trends Microbiol 2002 Aug; 10(8): 376-82

Neisseria meningitidis is a commensal bacterium of the human nasopharynx that occasionally provokes invasive disease. Carriage strains of N. meningitidis are heterogeneous, more frequent in nature and are transmitted among carriers. Disease is not a part of this transmission cycle and is caused by virulent strains. N. meningitidis is highly variable and variants that are modified in their virulence and/or transmissibility are continually generated. These events probably occur frequently, thus explaining not only the heterogeneous nature of meningococcal populations in carriers but probably also the evolutionary success of this human-restricted bacterium.