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© Research
Publication : PloS one

The balance of apoptotic and necrotic cell death in Mycobacterium tuberculosis infected macrophages is not dependent on bacterial virulence

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in PloS one - 30 Oct 2012

Butler RE, Brodin P, Jang J, Jang MS, Robertson BD, Gicquel B, Stewart GR

Link to Pubmed [PMID] – 23118880

PLoS ONE 2012;7(10):e47573

An important mechanism of Mycobacterium tuberculosis pathogenesis is the ability to control cell death pathways in infected macrophages: apoptotic cell death is bactericidal, whereas necrotic cell death may facilitate bacterial dissemination and transmission.