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© Research
Publication : PloS one

The balance of apoptotic and necrotic cell death in Mycobacterium tuberculosis infected macrophages is not dependent on bacterial virulence

Member: Brigitte Gicquel
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in PloS one - 30 Oct 2012

Butler RE, Brodin P, Jang J, Jang MS, Robertson BD, Gicquel B, Stewart GR

Link to Pubmed [PMID] – 23118880

PLoS ONE 2012;7(10):e47573

An important mechanism of Mycobacterium tuberculosis pathogenesis is the ability to control cell death pathways in infected macrophages: apoptotic cell death is bactericidal, whereas necrotic cell death may facilitate bacterial dissemination and transmission.