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© Research
Publication : Vector borne and zoonotic diseases (Larchmont, N.Y.)

Seroprevalence of Crimean-Congo Hemorrhagic Fever Among Small Ruminants from Southern Romania.

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Vector borne and zoonotic diseases (Larchmont, N.Y.) - 01 Jul 2022

Bratuleanu B, Anita A, Temmam S, Dascalu A, Crivei L, Cozma A, Pourquier P, Savuta G, Eloit M, Anita D

Link to Pubmed [PMID] – 35772004

Link to DOI – 10.1089/vbz.2021.0091

Vector Borne Zoonotic Dis 2022 Jul; 22(7): 397-401

Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne disease that can be contracted by direct contact with viremic animals or humans. Domestic animals are accidental hosts and contribute to the spread and amplification of the virus. The main objective of this study was to provide updated information related to CCHF virus (CCHFV) infection in Southern Romania by assessing the seroprevalence of CCHF in small ruminants (sheep and goats) using a double-antigen sandwich enzyme-linked immunosorbent assay and by detection of CCHFV in engorged ticks and serum samples using real-time RT-PCR. The overall seroprevalence of CCHF in small ruminants was 37.7% (95% CI 31.7 to 43.7). No statistical seroprevalence difference was observed between the two species of ruminants (p = 0.76), but a significant difference was established between the locations (p < 0.01). No CCHFV RNA was detected in tick pools and small ruminant's sera tested by real-time RT-PCR, although the high seroprevalence to CCHFV among ruminants indicates that CCHV or a closely related virus circulates in Southern Romania.