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© Research
Publication : Journal of computational biology : a journal of computational molecular cell biology

RNA locally optimal secondary structures

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of computational biology : a journal of computational molecular cell biology - 01 Oct 2012

Saffarian A, Giraud M, de Monte A, Touzet H

Link to Pubmed [PMID] – 23057822

J. Comput. Biol. 2012 Oct;19(10):1120-33

RNA locally optimal secondary structures provide a concise and exhaustive description of all possible secondary structures of a given RNA sequence, and hence a very good representation of the RNA folding space. In this paper, we present an efficient algorithm that computes all locally optimal secondary structures for any folding model that takes into account the stability of helical regions. This algorithm is implemented in a software called regliss that runs on a publicly accessible web server.

http://www.ncbi.nlm.nih.gov/pubmed/23057822