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© A. Alanio, E. Perret
Prolifération de Cryptococcus neoformans dans des macrophages murins.
Publication : American journal of infection control

Risk associated with a systematic search of extended-spectrum β-lactamase-producing Enterobacteriaceae

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in American journal of infection control - 11 Oct 2012

Prinapori R, Guinaud J, Khalil A, Lecuyer H, Gendrel D, Lortholary O, Nassif X, Viscoli C, Zahar JR

Link to Pubmed [PMID] – 23062579

Am J Infect Control 2013 Mar;41(3):259-60

We evaluated 74 children with previous fecal extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae colonization who were hospitalized and receiving a course of antibiotic therapy for suspected infection. Sixty-four patients (86.5%) received a carbapenem agent. Only 3 patients were infected with an ESBL-producing Enterobacteriaceae. Sixty-one (95%) initial antibiotic courses were considered excessive and required deescalation; however, deescalation was accomplished in only 38 patients (62%). This suggests the need for an ESBL control program to decrease carbapenem use and thereby limit carbapenem resistance in gram-negative bacilli.

http://www.ncbi.nlm.nih.gov/pubmed/23062579