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© Institut Pasteur
Culture de myotubes murins infectés par le virus de la rage fixe, observée en immunoflorescence indirecte.
Publication : Journal of neurovirology

Rabies virus receptors

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of neurovirology - 01 Feb 2005

Lafon M

Link to Pubmed [PMID] – 15804965

J. Neurovirol. 2005 Feb;11(1):82-7

There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind rabies virus and/or facilitate rabies virus entry into cells. Other components of the cell membrane, such as gangliosides, may also participate in the entry of rabies virus. However, little is known of the role of these molecules in vivo. This review proposes a speculative model that accounts for the role of these different molecules in entry and trafficking of rabies virus into the nervous system.

http://www.ncbi.nlm.nih.gov/pubmed/15804965