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© Research
Publication : Cellular microbiology

Organ-on-chip to investigate host-pathogens interactions.

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Cellular microbiology - 02 Apr 2021

Feaugas T, Sauvonnet N,

Link to Pubmed [PMID] – 33798273

Link to DOI – 10.1111/cmi.13336

Cell Microbiol 2021 Apr; ():

Infectious diseases remain the subject of intense research. This topic reaches a new era towards the study of host-pathogen interactions mechanisms at the tissue scale. The past few years have hence witnessed the emergence of new methods. Among them, organ-on-chip, which combines biomaterial technology, microfluidic and tissue engineering to recreate the organ physiology is very promising. This review summarizes how this technology recapitulates the architecture, the mechanical stimulation and the interface of a tissue and how this particular microenvironment is critical to study host-pathogen interactions. This article is protected by copyright. All rights reserved.

https://pubmed.ncbi.nlm.nih.gov/33798273