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© Research
Publication : Cell host & microbe

NKp30 enables NK cells to act naturally with fungi

Team: Immunology of Fungal Infections
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Cell host & microbe - 16 Oct 2013

Quintin J, Levitz SM

Link to Pubmed [PMID] – 24139394

Cell Host Microbe 2013 Oct;14(4):369-71

NK cells have direct activity against fungal pathogens. Using an unbiased systematic approach, Li et al. (2013) find that NKp30 is a major NK cell receptor responsible for fungal recognition. Moreover, diminished NKp30 expression is associated with reduced antifungal activity in NK cells isolated from HIV-infected persons.