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© Research
Publication : AIDS

New CCR5 variants associated with reduced HIV coreceptor function in southeast Asia

Team: Functional Genetics of Infectious Diseases
Member: Marie Nguyen-De Bernon
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in AIDS - 19 Nov 2004

Capoulade-Métay C, Ma L, Truong LX, Dudoit Y, Versmisse P, Nguyen NV, Nguyen M, Scott-Algara D, Barré-Sinoussi F, Debré P, Bismuth G, Pancino G, Theodorou I

Link to Pubmed [PMID] – 15577536

AIDS 2004 Nov;18(17):2243-52

Despite multiple exposure to HIV-1, some individuals remain uninfected. This resistance has been associated with homozygosity for a 32 base pair deletion in the gene for the CCR5 receptor. This variant occurs frequently in Caucasians but is extremely rare in Asians or Africans.

http://www.ncbi.nlm.nih.gov/pubmed/15577536