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© Fabrice Chrétien with Ultrapole, colorized by Jean-Marc Panaud
Cellule souche (en jaune) de muscle squelettique partiellement recouverte par la membrane basale, migrant sur une fibre musculaire (en bleu).
Publication : Immunology and allergy clinics of North America

Neuropsychological features of adult mastocytosis

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Immunology and allergy clinics of North America - 01 May 2014

Moura DS, Georgin-Lavialle S, Gaillard R, Hermine O

Link to Pubmed [PMID] – 24745683.

Immunol Allergy Clin North Am 2014 May;34(2):407-22

In approximately one-third of cases, patients with mastocytosis can display various disabling general and neuropsychological symptoms. General signs may have a major impact on quality of life. Neurologic symptoms are less frequent. In a majority of cases, the pathophysiology of these symptoms is not known but could be linked to tissular mast cell infiltration, mast cell mediator release, or both. Treatments aiming at reducing mast cell number and/or stabilizating mast cells may be useful. Preliminary results suggest that treatment with kinase inhibitors may improve symptoms of depression and cognitive impairment.

http://www.ncbi.nlm.nih.gov/pubmed/24745683.