Mucosal lymphoid infiltrate dominates colonic pathological changes in murine experimental shigellosis

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Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase

Lethal giant larvae controls the localization of notch-signaling regulators numb, neuralized, and Sanpodo in Drosophila sensory-organ precursor cells

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Published in The Journal of infectious diseases - 31 May 2005

Martino MC, Rossi G, Martini I, Tattoli I, Chiavolini D, Phalipon A, Sansonetti PJ, Bernardini ML

Link to Pubmed [PMID] – 15942903

J. Infect. Dis. 2005 Jul;192(1):136-48

Shigella species are invasive human pathogens that cause acute rectocolitis by triggering a dysregulated inflammatory reaction in the colonic and rectal mucosa. Because mice are naturally resistant to shigellosis, there is no mouse model that mimics human disease. We explore the susceptibility of intestinal flora-depleted mice to shigellosis after intragastric infection with Shigella strains.

Published on: 31 May 2005