Monitoring of Bordetella isolates circulating in Saint Petersburg, Russia between 2001 and 2009 - Research - Institut Pasteur

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Structural characterization of the stem-stem dimerization interface between prolactin receptor chains complexed with the natural hormone

The stromal gene encoding the CD274 antigen as a genetic modifier controlling survival of mice with γ-radiation-induced T-cell lymphoblastic lymphomas.

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Published in Research in microbiology - 24 Sep 2010

Kurova N, Njamkepo E, Brun D, Tseneva G, Guiso N

Link to Pubmed [PMID] – 20870020

Res. Microbiol. 2010 Dec;161(10):810-5

Bordetella isolates in the Saint Petersburg region have been monitored since 1998. Over the past ten years, concomitant with the increase in pertussis whole-cell vaccine coverage, the incidence of whooping cough has decreased. However, this decrease exists only for Bordetella pertussis infections, as the incidence of Bordetella parapertussis confirmed cases has remained stable, suggesting that pertussis-vaccine-induced immunity is not protective against parapertussis, as expected. B. pertussis and B. parapertussis clinical isolates were analyzed using serotyping, immunoblotting, pulsed-field gel electrophoresis of chromosomal DNA (after digestion with XbaI) and sequencing of virulence genes. The bacterial population is now similar to that observed in other European countries.

Published on: 24 Sep 2010